Hua Lv

ORCID: 0009-0004-5329-5014
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About
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Research Areas
  • Advanced Photocatalysis Techniques
  • Copper-based nanomaterials and applications
  • Gas Sensing Nanomaterials and Sensors
  • Mathematical Biology Tumor Growth
  • ZnO doping and properties
  • Glioma Diagnosis and Treatment
  • Cancer therapeutics and mechanisms
  • Ga2O3 and related materials
  • Quantum Dots Synthesis And Properties
  • Cancer Mechanisms and Therapy
  • Lung Cancer Treatments and Mutations
  • 2D Materials and Applications
  • Perovskite Materials and Applications
  • Pharmacological Effects of Natural Compounds
  • Natural product bioactivities and synthesis
  • TiO2 Photocatalysis and Solar Cells
  • Traditional Chinese Medicine Analysis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Covalent Organic Framework Applications
  • Pharmacogenetics and Drug Metabolism
  • Nanocluster Synthesis and Applications
  • Ginseng Biological Effects and Applications
  • MRI in cancer diagnosis
  • Crystallization and Solubility Studies
  • Avian ecology and behavior

Ningxia Medical University
2024-2025

Sir Run Run Shaw Hospital
2025

Zhejiang University
2025

China National Petroleum Corporation (China)
2022-2025

China Pharmaceutical University
2005-2024

Taizhou University
2020-2024

Henan Normal University
2015-2024

Foshan University
2024

Yuxi Normal University
2022

Roche (China)
2020-2021

Chitosan-based active films were developed by incorporation of carvacrol (10 g/L), pomegranate peel extract (PPE, 10 g/L) and + PPE g/L each) their physical, antioxidant antimicrobial properties investigated. Incorporation into the significantly decreased water vapor permeability, tensile strength percentage elongation at break. carvacrol, transparency, but increased total phenol content activity. All films, with exception PPE-incorporated film, exhibited antibacterial activity against...

10.3390/molecules200611034 article EN cc-by Molecules 2015-06-15

The hydrodynamic and structural properties of Microcystis extracellular polymeric substances (EPS) in electrolytes with different valences ionic strengths were investigated via using dynamic light scattering, the fluorescence excitation emission matrix coupled parallel factor (EEM-PARAFAC) analysis, two-dimensional correlation spectroscopy (2D-COS), cryogenic transmission electron microscopy (Cryo-TEM). diameters EPS colloids exhibited no variation for monovalent NaCl but a substantial...

10.1021/acs.est.6b00129 article EN Environmental Science & Technology 2016-08-09

The rise of multidrug resistant (MDR) Gram-negative (GN) pathogens and the decline available antibiotics that can effectively treat these severe infections are a major threat to modern medicine. Developing novel against MDR GN is particularly difficult as compounds have permeate double membrane, which has very different physicochemical properties, circumvent plethora resistance mechanisms such multiple efflux pumps target modifications. bacterial type II topoisomerases DNA gyrase (GyrA2B2)...

10.1021/acs.jmedchem.0c00768 article EN Journal of Medicinal Chemistry 2020-08-04

Mutations of isocitrate dehydrogenase 1 (IDH1) are frequently found in certain cancers such as glioma. Different from the wild-type (WT) IDH1, mutant enzymes catalyze reduction α-ketoglutaric acid to d-2-hydroxyglutaric (D2HG), leading cancer initiation. Several 1-hydroxypyridin-2-one compounds were identified be inhibitors IDH1(R132H). A total 61 derivatives synthesized, and their structure–activity relationships investigated. Potent IDH1(R132H) with Ki values low 140 nM, while they possess...

10.1021/jm500660f article EN publisher-specific-oa Journal of Medicinal Chemistry 2014-10-01

Microglial activation is the initial pathological event that occurs in demyelination, a prevalent feature various neurological diseases. G protein-coupled estrogen receptor (GPER1), which highly expressed microglia, has been reported to reduce myelin damage. However, precise molecular mechanisms involved remain unclear. In this study, cuprizone (CPZ) -induced demyelination model was used investigate relationship between GPER1 and sheath injury its mechanism. The results demonstrated...

10.1016/j.jbc.2025.108312 article EN cc-by-nc-nd Journal of Biological Chemistry 2025-02-01

Background/Objectives: Ropivacaine is primarily metabolized by the liver. High doses of ropivacaine, combined with altered pharmacokinetics due to hepatectomy, raise concerns about potential drug toxicity. We investigated impact LMH (laparoscopic major hepatectomy) on high-dose ropivacaine. Methods: Ten patients undergoing received a BD-TAP (bilateral dual transversus abdominis plane) block high dose ropivacaine (3 mg·kg−1 in 60 mL). Plasma concentrations total and free AAG (alpha-1 acid...

10.3390/pharmaceutics17030386 article EN cc-by Pharmaceutics 2025-03-18

Achieving high-performance electronic structure engineering in multi-component photocatalysts that enable effective cooperation and synergy photoinduced charge transfer surface reaction kinetics remains a major challenge for the sustainable conversion...

10.1039/d4qi03266g article EN Inorganic Chemistry Frontiers 2025-01-01

The positive synergetic effects among g-C<sub>3</sub>N<sub>4</sub>, Cu<sub>2</sub>(OH)<sub>2</sub>CO<sub>3</sub> and fluorescein dramatically boost the H<sub>2</sub>-evolution activity over a fluorescein-sensitized Cu<sub>2</sub>(OH)<sub>2</sub>CO<sub>3</sub>/g-C<sub>3</sub>N<sub>4</sub> photocatalyst.

10.1039/c8dt03579b article EN Dalton Transactions 2018-11-09
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