Nan Jia

ORCID: 0009-0004-6410-6303
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Nanocluster Synthesis and Applications
  • Protein Hydrolysis and Bioactive Peptides
  • Advanced Nanomaterials in Catalysis
  • Algal biology and biofuel production
  • Complement system in diseases
  • Proteins in Food Systems
  • Collagen: Extraction and Characterization
  • Aquaculture Nutrition and Growth
  • Mass Spectrometry Techniques and Applications
  • Advanced Chemical Sensor Technologies
  • Ginseng Biological Effects and Applications
  • Heavy Metals in Plants
  • Auditing, Earnings Management, Governance
  • Phytochemistry and biological activity of medicinal plants
  • Seaweed-derived Bioactive Compounds
  • Outsourcing and Supply Chain Management
  • Meat and Animal Product Quality
  • Molecular Biology Techniques and Applications
  • Organoboron and organosilicon chemistry
  • Crystallography and molecular interactions
  • Heme Oxygenase-1 and Carbon Monoxide
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Hydrocarbon exploration and reservoir analysis
  • Lipid Membrane Structure and Behavior

Fujian Agriculture and Forestry University
2025

College of Marin
2025

Northwest University
2021-2024

State Key Laboratory of Continental Dynamics
2024

Northeast Petroleum University
2024

Ministry of Education of the People's Republic of China
2021-2024

Ocean University of China
2021-2023

East China University of Science and Technology
2021

Northeast Forestry University
2018-2020

Hebei University
2019

Metal nanoclusters (NCs) have emerged as a promising class of fluorescent probes for cellular imaging due to their high resistance photobleaching and low toxicity. Nevertheless, widespread use in clinical diagnosis is limited by unstable intracellular fluorescence. In this study, we develop an intracellularly biosynthesized probe, DNA nanoribbon-gold NCs (DNR/AuNCs), long-term tracking. Our results show that DNR/AuNCs exhibit 4-fold enhancement fluorescence intensity compared free AuNCs. We...

10.1021/jacsau.3c00365 article EN cc-by-nc-nd JACS Au 2023-09-06

Near-infrared fluorescence (NIRF) probes greatly facilitate in vivo imaging of various biologically important species. However, there are several significant limitations such as consuming washing steps, photobleaching, and low signal intensity. Herein, we synthesized fluorescent copper nanosheets templated with DNA scaffolds (DNS/CuNSs). We employ them Cy5.5 the resonance energy transfer (FRET) system, which have a larger Stokes shift (∼12-fold) than traditional NIRF dye Cy5.5. Based on...

10.1021/acs.analchem.3c04644 article EN Analytical Chemistry 2024-01-24

The main goal of this study is to improve the bioactivity citrus pomace by subjecting it solid-state fermentation Lactobacillus acidophilus, casei, and plantarum over varying periods time. viability Lactobacillus, as well total phenolic content (TPC) antioxidant capacity (TAC) values orange (OP), varied depending on species period. incorporation into juice samples at a ratio 5% considerably enhanced probiotics. TPC TAC were reduced after fermentation. addition significantly increased...

10.1021/acsomega.4c09704 article EN cc-by-nc-nd ACS Omega 2025-03-13

Herein, a highly selective and sensitive "OFF–ON" fluorescent biosensor was designed for intracellular Cu2+ detection. Compared to the biosensors reported so far, this work tackled tricky issue of reliability Cu2+, which mainly depends on integration high selectivity Cu(I)-catalyzed click reaction with ultrahigh sensitivity spherical nucleic acid-based 3D DNA walker. Typically, track is carried out by coconjugating N3-S1 Cy3-HP onto gold nanoparticles (AuNPs). On state, fluorophore (Cy3)...

10.1021/acsabm.1c00073 article EN ACS Applied Bio Materials 2021-03-23

Skp derived from Escherichia coli attracts leukocytes as a pure chemotactic ligand of the C5a receptor. We identified submolecular region that binds and activates receptor to be -Gln103-Asp104-Arg105- using synthetic peptide fragments site-directed mutants Skp. As amino acid residue equivalent Gln103 is Leu72, we prepared Gln103Leu-Skp mutant recombinant protein. With this mutation, gained secretagogue functions including induction respiratory burst granule release reactions leukotriene...

10.1189/jlb.1009649 article EN Journal of Leukocyte Biology 2010-01-20

Collagens, being the abundant structural proteins in many animal-derived food materials, generally assemble hierarchical level of collagen fibrils. Our previous study found that sea cucumber fibrils are covalently connected with fucosylated chondroitin sulfate (fCS), giving an indication one special molecular form materials. Herein, this aimed to investigate properties and gastrointestinal digestion fate fCS. The presence covalent fCS could regulate rheological change more ordered secondary...

10.1016/j.jff.2023.105522 article EN cc-by-nc-nd Journal of Functional Foods 2023-04-04

Oxidative damage caused by the ferryl hemoglobin is one of major clinical adverse reactions hemoglobin-based oxygen carriers (HBOCs), while production reactive species in a pathological state can oxidize (HbFe2+ ) to Hb, which then enter pseudoperoxidase cycle, making highly toxic. In this study, we found that ferrous and polymerized porcine (one HBOCs) have peroxidase activity different from ferric hemoglobin. Ferrous catalyze reaction tyrosine (Tyr) with hydrogen peroxide. addition,...

10.1111/aor.14009 article EN Artificial Organs 2021-06-09

In this study, we describe a brief, sensitive and safe organic dye-based staining method for the visualization of DNA both in agarose polyacrylamide gels by using Victoria Pure Blue BO (VPBBO). Down to 0.8-1.6 ng λ DNA/HindIII markers 0.4-0.8 pUC18 DNA/Mspl can be successfully detected within 15 10 min new developed technique, respectively. Moreover, mechanism VPBBO was investigated further confirmed electrospray ionization mass spectrometry (ESI-MS) molecular docking. The results indicated...

10.1039/c2an36079a article EN The Analyst 2012-12-10

PCAOB once issued an article challenging US accounting firms' practice of outsourcing the audit US-listed Chinese companies. By analysing China concepts stocks audited by firms from 2001 to 2012, this paper seeks find optimal mode for cross-country auditing. The study shows that integration and alliance have significantly higher quality than non-alliance outsourcing, although no significant difference has been found between former two modes. However, as length cooperation extends, improves...

10.1080/21697213.2016.1196058 article EN China Journal of Accounting Studies 2016-04-02

We described herein the first example associated with B(C 6 F 5 ) 3 -catalyzed preparation of phosphoryl amides under mechanochemical conditions.

10.1039/d1cy01314a article EN Catalysis Science & Technology 2021-01-01

Asparagus dabieshanensis, a new species from the Dabie Mountains, Central China, is described and illustrated. Morphologically, it similar to A. cochinchinensis (Lour.) Merr. filicinus D. Don, but differs in having long straight cladodes, shorter pedicel than that of last two species. Molecular phylogenetic analysis based on combined four DNA markers (trnH-psbA, trnD-trnT, ndhF, phyC) indicated sister with strong support.

10.11646/phytotaxa.641.2.7 article EN Phytotaxa 2024-03-18
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