A5092827000- SARS-CoV-2 and COVID-19 Research
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Digestive system and related health
- Molecular Biology Techniques and Applications
- interferon and immune responses
- Radiation Therapy and Dosimetry
- Viral gastroenteritis research and epidemiology
- CRISPR and Genetic Engineering
- Cancer-related Molecular Pathways
- PARP inhibition in cancer therapy
- COVID-19 Clinical Research Studies
- Genetics and Neurodevelopmental Disorders
Universidade Federal do Pará
2023-2024
Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2. Genome-wide association studies (GWASs) have suggested a strong of genetic factors with the severity disease. However, many these been completed in European populations, and little known about variability indigenous peoples’ underlying The objective study to investigate variants present genes AQP3, ARHGAP27, ELF5L, IFNAR2, LIMD1, OAS1 UPK1A, selected due their COVID-19, sample people from Brazilian Amazon order...
Prostate cancer, according to the World Health Organization (WHO), ranks as fourth most prevalent type in population, even though it is highly frequent when detected early and promptly treated, resulting a low mortality rate. However, some cases, despite adherence proper clinical protocols, there progression castration-resistant prostate cancer (CRPC). In these outlined guidelines such those developed by National Comprehensive Cancer Network (NCCN), one approach involves utilization of...
COVID-19 is a systemic disease caused by the etiologic agent SARS-CoV-2, first reported in Hubei Province Wuhan, China, late 2019. The SARS-CoV-2 virus has evolved over time with distinct transmissibility subvariants from ancestral lineages. clinical manifestations of vary according to their severity and can range asymptomatic severe. Due rapid evolution pandemic, epidemiological studies have become essential understand effectively combat COVID-19, as incidence mortality this between...
Gastric Cancer is a disease associated with environmental and genetic changes, becoming one of the most prevalent cancers around world high incidence in Brazil. However, despite being highly studied neoplastic type, few efforts are aimed at populations unique background profile, such as indigenous peoples Brazilian Amazon. Our study characterized molecular profile five genes risk developing gastric cancer by sequencing complete exome 64 individuals belonging to 12 different The analysis...
Radiotherapy is focused on the tumor but also reaches healthy tissues, causing toxicities that are possibly related to genomic factors. In this context, radiogenomics can help reduce toxicity, increase effectiveness of radiotherapy, and personalize treatment. It important consider profiles populations not yet studied in radiogenomics, such as indigenous Amazonian population. Thus, our objective was analyze genes for ATM, TGFB1, RAD51, AREG, XRCC4, CDK1, MEG3, PRKCE, TANC1, KDR, people draw a...