Chengcheng Zhou

ORCID: 0009-0004-8562-2585
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About
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Research Areas
  • Cancer Cells and Metastasis
  • GABA and Rice Research
  • Epigenetics and DNA Methylation
  • Educational Technology and Pedagogy
  • Metabolomics and Mass Spectrometry Studies
  • Glycosylation and Glycoproteins Research
  • Ferroptosis and cancer prognosis
  • RNA and protein synthesis mechanisms
  • MicroRNA in disease regulation
  • Human Pose and Action Recognition
  • Lung Cancer Treatments and Mutations
  • CRISPR and Genetic Engineering
  • Video Analysis and Summarization
  • Lung Cancer Research Studies
  • Adipose Tissue and Metabolism
  • RNA modifications and cancer
  • RNA Research and Splicing

Nantong University
2025

Guangzhou Medical University
2012-2022

Recent advancements in contemporary therapeutic approaches have increased the survival rates of lung cancer patients; however, long-term benefits remain constrained, underscoring pressing need for novel biomarkers. Surfactant-associated 3 (SFTA3), a long non-coding RNA predominantly expressed normal epithelial cells, plays crucial role development. Nevertheless, its function adenocarcinoma (LUAD) remains inadequately understood. Single-cell sequencing data were utilized to identify...

10.1186/s12885-024-13395-z article EN cc-by-nc-nd BMC Cancer 2025-01-08

Cancer stem cells (CSCs) play important roles in occurrence, development, recurrence and metastasis of cancer.Isolation identification CSCs have been performed from some cancer tissues or cells.In this paper, human lung adenocarcinoma were induced isolated SPC-A1 their characteristics determined.SPC-A1 cultured serum-free medium epidermal growth factor basic fibroblast added into the to induce formation multicellular tumor spheroids.The results showed that floating spheroids (named...

10.4149/neo_2012_087 article EN Neoplasma 2012-01-01

Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is an autosomal recessive gamma-aminobutyric acid (GABA) metabolism disorder that can arise due to ALDH5A1 mutations, resulting in severe, progressive, untreatable neurodegeneration. SSADH-D primarily studied using simplified models, such as HEK293 cells overexpressing genes of interest, but overexpression result protein aggregation or pathway saturation may not be representative actual underlying disease phenotypes.We used a...

10.1186/s12868-022-00755-3 article EN cc-by BMC Neuroscience 2022-12-16

The aim of the study was to define specific genetic profile in Ta and T1 urinary bladder carcinoma patients with without recurrence by gene expression microarrays.Eleven time shorter than one year (patients recurrence) 11 longer 4 years were enrolled.Data from microarrays subjected a panel statistical analyses identify cancer recurrence-associated signatures.Initial screening using GeneSpring Bioconductor software tools revealed putative set 47 genes differing both groups.After validation,...

10.4149/neo_2013_039 article EN Neoplasma 2013-01-30

In order to improve the effect of sports strategy formulation, this paper combines artificial intelligence assisted agile Internet Things conduct research on simulation scheme, and builds an intelligent system.The model designed in can change mechanism parameters according actual situation moving object, establish fixed coordinate system local parallel platform model, mathematical platform.Moreover, principle vector closure, inverse kinematics position solution is analyzed, kinematic...

10.14733/cadaps.2023.s12.57-72 article EN Computer-Aided Design and Applications 2023-05-12

Abstract Background: Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is an autosomal recessive gamma-aminobutyric acid (GABA) metabolism disorder that can arise due to ALDH5A1 mutations, resulting in severe, progressive, untreatable neurodegeneration. The SSADH-D primarily studied using simplified model symptoms such as HEK293 cells overexpressing genes of interest, but overexpression result protein aggregation or pathway saturation may not be representative actual underlying...

10.21203/rs.3.rs-1577928/v1 preprint EN cc-by Research Square (Research Square) 2022-06-14
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