Hamad Al Shahi

ORCID: 0009-0004-9850-6102
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About
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Research Areas
  • Adipose Tissue and Metabolism
  • Vehicular Ad Hoc Networks (VANETs)
  • Muscle Physiology and Disorders
  • Advanced Authentication Protocols Security
  • Insect Pest Control Strategies
  • Fatty Acid Research and Health
  • Mitochondrial Function and Pathology
  • IoT and Edge/Fog Computing
  • Aortic aneurysm repair treatments
  • Atrial Fibrillation Management and Outcomes
  • Nanomaterials for catalytic reactions
  • IL-33, ST2, and ILC Pathways
  • Exercise and Physiological Responses
  • Cardiac Fibrosis and Remodeling
  • Carbon dioxide utilization in catalysis
  • Chemotherapy-induced organ toxicity mitigation
  • Eicosanoids and Hypertension Pharmacology
  • Catalytic Processes in Materials Science
  • Medicinal Plants and Neuroprotection
  • Context-Aware Activity Recognition Systems
  • Sesame and Sesamin Research
  • Piperaceae Chemical and Biological Studies
  • Curcumin's Biomedical Applications
  • Inflammasome and immune disorders
  • Cardiovascular Function and Risk Factors

Jazan University
2023-2025

University of Ha'il
2024

Taibah University
2024

Juntendo University
2015-2020

Background:Dietary intake of ω3 polyunsaturated fatty acids (ω3-PUFAs) reduces progression atherosclerosis and prevents future cardiovascular events. Macrophages are key players in the pathogenesis aortic aneurysm. The effects ω3-PUFAs on abdominal aneurysm (AAA) formation macrophage-mediated inflammation remain unclear.Methods Results:The AAA model was developed by angiotensin II infusion apolipoprotein E-deficient mice. Mice were supplemented with eicosapentaenoic acid (EPA) or...

10.1253/circj.cj-14-0471 article EN Circulation Journal 2015-01-01

Objective . We evaluated inflammatory cytokines and chemokine in peripheral blood mononuclear cells (PBMCs) patients with either acute coronary syndrome (ACS) or stable artery disease (CAD). Methods enrolled 20 ACS 50 CAD without previous history of who underwent cardiac catheterization. Patients an estimated glomerular filtration rate ≤30 mL/min/1.73 m 2 C-reactive protein ≥1.0 mg/dL were excluded. Blood samples collected from the just before catheterization, PBMCs isolated whole blood. The...

10.1155/2015/805375 article EN cc-by International Journal of Vascular Medicine 2015-01-01

Omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) have been reported to reduce the risk of cardiovascular disease. However, whether omega-3 PUFAs are involved in pathogenesis abdominal aortic aneurysms (AAA) remains unclear.We analyzed 67 consecutive patients admitted for elective surgical repair AAA. We investigated association serum EPA DHA levels well EPA/AA ratio with size AAA assessed using three-dimensional reconstructed computed...

10.5551/jat.38315 article EN Journal of Atherosclerosis and Thrombosis 2017-01-01

Postprandial hyperglycemia plays an important role in the pathogenesis of coronary artery disease and cardiovascular events. Serum 1,5-anhydroglucitol (1,5-AG) levels are known to be a clinical marker postprandial hyperglycemia. However, impact 1,5-AG level on events has not been fully investigated. We enrolled 240 consecutive patients who had undergone first-time elective percutaneous intervention (PCI) with follow-up angiography within 1 year. excluded history acute syndrome, advanced...

10.1186/s12933-016-0459-5 article EN cc-by Cardiovascular Diabetology 2016-10-11

Background: Muscle wasting is a debilitating phenotype associated with chronic heart failure. We have previously demonstrated that angiotensin II (AII) directly induces muscle in mice through the activation of NADPH oxidase. In this study, we tested hypothesis deficiency oxidase 4 (Nox4), major source oxidative stress, ameliorates AII-induced regulation redox balance. Methods and Results: Nox4 knockout (KO) wild-type (WT) were used. At baseline, there no differences physical characteristics...

10.3389/fphys.2018.00340 article EN cc-by Frontiers in Physiology 2018-04-05

Cypermethrin (Cyp) is a pyrethroid that has been associated with the toxicity of various organs. The aim our study was to evaluate hepatoprotective and antioxidant activities nano-piperine (NP) against Cyp toxicity. (50 mg/kg) administered orally in all animals groups III-VI for 15 days. Groups IV-VI each received three doses NP (125, 250, 500 µg/kg/day) 10 days after receiving dosage, which given 1 h. A rise serum biomarkers (ALT, AST, ALP, total protein, albumin), are indicators alongside...

10.3390/ijms242015361 article EN International Journal of Molecular Sciences 2023-10-19

Cyclophosphamide, an alkylating agent integral to specific cancer chemotherapy protocols, is often curtailed in application owing its significant hepatotoxic side effects. Therefore, this study was conducted assess the hepatoprotective potential of sesamin, a plant-originated antioxidant, using rat models. The rats were divided into five groups: control group received only vehicle for six days; cyclophosphamide intraperitoneal (i.p.) single injection (150 mg/kg) on day four; sesamin daily...

10.3390/biomedicines11123238 article EN cc-by Biomedicines 2023-12-07

Vehicular fog systems that are enabled by fifth-generation (5G) networks can significantly improve traffic safety and efficiency through vehicle-to-vehicle communication. Vehicles must have their legal status verified before they join the network, as vehicular depend on open Consequently, several anonymous authentication schemes been created to withstand malicious vehicles, with foundations being bilinear pairing or elliptic curve cryptography. But quantum attacks easily defeat these...

10.1109/access.2024.3402336 article EN cc-by-nc-nd IEEE Access 2024-01-01

Risk factors for atrial fibrillation (AF) recurrence in patients who have undergone AF catheter ablation not been fully clarified. The objective of this study was to assess whether the left atrium (LA) and LA appendage (LAA) volumes, cardio-metabolic markers such as polyunsaturated fatty acids (PUFAs) levels were associated with recurrence.Seventy-seven consecutive (mean age, 59 ± 8 years; male, 81%; paroxysmal AF, 64%) undergoing enrolled. Using contrast-enhanced cardiac multi-detector...

10.14740/cr542w article EN Cardiology Research 2017-01-01

Abstract We investigated the effects of voluntary exercise after myocardial infarction (MI) on cardiac function, remodeling, and inflammation. Male C57BL/6J mice were divided into following four groups: sedentary + sham (Sed-Sh), MI (Sed-MI), (Ex-Sh), (Ex-MI). induction was performed by ligation left coronary artery. Exercise consisting wheel running started operation continued for 4 weeks. The Ex-MI had significantly increased function compared with Sed-MI mice. showed reduced expression...

10.1515/med-2020-0109 article EN Open Medicine 2020-01-01

Calotropis procera, a plant belonging to the Asclepiadaceae family, with significant therapeutic potential. Indigenous arid regions of India, Africa, and China, procera is recognized for its diverse biological activities, including anti-inflammatory, antimicrobial, hypoglycemic, anticancer properties. This review focuses on potential highlighting relevance in traditional medicine emerging role modern applications. Despite promising medicinal value, also associated toxicity, particularly...

10.47310/jpms2024130706 article EN Journal of Pioneering Medical Science 2024-12-30

Background: Risk factors for atrial fibrillation (AF) recurrence in patients undergoing catheter ablation (CA) are unclear. We assessed whether left atrium (LA) and LA appendage (LAA) volume, cardio-metabolic markers such as oxidative glycation stresses, endothelial function, polyunsaturated fatty acids (PUFAs) levels were associated with AF recurrence. Methods: Seventy-seven consecutive first-time CA (mean age, 59 ± 8 years; male, 81%; paroxysmal AF, 65%; chickenwing morphology, 49%)...

10.1161/circ.134.suppl_1.13231 article EN Circulation 2016-11-11
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