A5005597238- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Plant Reproductive Biology
- Photosynthetic Processes and Mechanisms
- Synthetic Organic Chemistry Methods
- Catalytic C–H Functionalization Methods
- Advanced biosensing and bioanalysis techniques
- Industrial Automation and Control Systems
- Microbial Applications in Construction Materials
- Catalytic Cross-Coupling Reactions
- Nuclear Receptors and Signaling
- Advanced Image Processing Techniques
- Lipid metabolism and biosynthesis
- Image and Signal Denoising Methods
- Nanocomposite Films for Food Packaging
- Parkinson's Disease Mechanisms and Treatments
- RNA modifications and cancer
- MicroRNA in disease regulation
- TiO2 Photocatalysis and Solar Cells
- Bacterial biofilms and quorum sensing
- Alzheimer's disease research and treatments
- Numerical methods in engineering
- Axial and Atropisomeric Chirality Synthesis
- Ethics and Social Impacts of AI
Yangtze University
2023-2025
Key Laboratory of Drilling and Production Engineering for Oil and Gas, Hubei Province
2025
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation
2025
University of Science and Technology Beijing
2018-2024
Northeastern University
2016-2024
Hunan University of Traditional Chinese Medicine
2022-2024
Jiamusi University
2024
Second Affiliated Hospital of Zhengzhou University
2019-2023
China Pharmaceutical University
2021-2023
Shandong Provincial Hospital
2022
Understanding the molecular basis of male sterility and developing practical male-sterility systems are essential for heterosis utilization commercial hybrid seed production in crops. Here, we report regulation by genic gene maize 7 (ZmMs7) its application a dominant system multiple species. ZmMs7 is specifically expressed anthers, encodes plant homeodomain (PHD) finger protein that functions as transcriptional activator, plays key role tapetal development pollen exine formation. can...
Reactions involving allenyl ion intermediates have been widely applied in the synthesis of functionalized allenes, but reactions radicals less studied and limited successful examples realized mainly by transition metal catalysis. We herein demonstrate generation N-heterocyclic carbene (NHC) organocatalysis their applications three-component radical relay 1,4-alkylcarbonylation 1,3-enynes without participation. This strategy could accommodate a collection different alkyl precursors such as...
Atropisomers bearing multiple stereogenic axes are of increasing importance to the field material science, pharmaceuticals, and catalysis. However, atroposelective construction multi-axis atropisomers remains rare challenging, due intrinsical difficulties in stereo-control axes. Herein, we demonstrate a single-step new class 1,2-diaxially chiral triaryl α-pyranones by an N-heterocyclic carbene organocatalytic asymmetric [3+3] annulation well-designed alkynyl acylazolium precursors enolizable...
Map-based cloning of maize ms33 gene showed that ZmMs33 encodes a sn-2 glycerol-3-phosphate acyltransferase, the ortholog rice OsGPAT3, and it is essential for male fertility in maize. Genetic sterility has been widely studied its biological significance commercial value hybrid seed production. Although many male-sterile mutants have identified (Zea mays L.), likely most genes cause are unknown. Here, we report recessive genetic mutant, sterility33 (ms33), which displays small, pale yellow...
There is growing evidence of the position microRNAs (miRs) in Alzheimer's disease (AD), thus our objective was to discuss impact miR-129-5p regulating nerve injury and inflammatory response AD rats by modulating SOX6 expression. The rat model established injecting Aβ25-35 into brain. pathological changes, ultrastructure, number neurons, cell degeneration apoptosis hippocampal tissue were observed vivo. MiR-129-5p, SOX6, IL-1β, TNF-α, Bcl-2 Bax expression serum tissues detected ELISA, RT-qPCR...
Fatty acyl reductases (FARs) catalyse the reduction of fatty acyl-coenzyme A (CoA) or -acyl carrier protein (ACP) substrates to primary alcohols, which play essential roles in lipid metabolism plants. However, mechanism by FARs are involved male reproduction is poorly defined. Here, we found that two maize allelic mutants, ms25-6065 and ms25-6057, displayed defective anther cuticles, abnormal Ubisch body formation, impaired pollen exine formation complete sterility. Based on map-based...
The machine learning and data science community has made significant while dispersive progress in accelerating transformer-based large language models (LLMs), one promising approach is to replace the original causal attention a generative pre-trained transformer (GPT) with \emph{exponentially decaying linear attention}. In this paper, we present LeetDecoding, which first Python package that provides set of computation routines for fundamental operator. launch LeetDecoding was motivated by...
Genic male sterility (GMS) mutant is a useful germplasm resource for both theory research and production practice. The identification characterization of GMS genes, assessment male-sterility stability under different genetic backgrounds in Zea may (maize) have (1) deepened our understanding the molecular mechanisms controlling anther pollen development, (2) enabled development efficient use many biotechnology-based (BMS) systems hybrid breeding. Here, we reported complete (ms20), which...
Through β-activation of alkynoic acid esters with N-heterocyclic carbene catalysis, a formal [3+3] annulation alkynyl acylazoliums indolin-3-ones has been developed for the rapid construction structurally interesting benzofuro[3,2-b]pyridin-2-ones potential bioactivities. This protocol provides highly efficient and simple method synthesis target molecules under mild reaction conditions wide substrate scope excellent chemoselectivity. The synthetic utility this was also demonstrated by...
An unprecedented organocatalytic asymmetric construction of novel six-membered carbocycle fused uracils has been demonstrated by the reaction remotely enolizable 6-methyluracil-5-carbaldehydes with 2-bromoenals. The involves an N-heterocyclic carbene-catalyzed formal [4 + 2] annulation o-quinodimethane (oQDM) dienolates α,β-unsaturated acylazoliums, followed a cascade lactone formation/decarboxylation process. This protocol unlocks new platform to access enantioenriched carbocycle-fused uracils.
Objective: Paraoxonase (PON) family genes are closely related to the etiology and prognosis of cerebral infarction. This study explored association promoter methylation PON (PON1, PON2 PON3) with risk Materials methods: In this study, 152 patients confirmed infarction were selected as case group, healthy controls control group. The quantitative methylation-specific PCR (qMSP) was used determine levels PON1, PON3 genes. level expressed a reference percentage (PMR). Results: Our results...