A5100722769- Plant Reproductive Biology
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Bacterial Genetics and Biotechnology
- RNA modifications and cancer
- Genetic Mapping and Diversity in Plants and Animals
- Lipid metabolism and biosynthesis
- Protein Structure and Dynamics
- Plant Virus Research Studies
- Microbial Metabolic Engineering and Bioproduction
- Plant Stress Responses and Tolerance
- Vibrio bacteria research studies
- Cancer Treatment and Pharmacology
- Plant and Fungal Interactions Research
- Hemoglobin structure and function
- Bacterial biofilms and quorum sensing
- Heme Oxygenase-1 and Carbon Monoxide
- Renal and related cancers
- Autophagy in Disease and Therapy
- Sesquiterpenes and Asteraceae Studies
- Phytoplasmas and Hemiptera pathogens
- Gait Recognition and Analysis
- Plant biochemistry and biosynthesis
- Heat shock proteins research
- Angiogenesis and VEGF in Cancer
Wuhan Institute of Technology
2022
First Affiliated Hospital of Jiamusi University
2022
Center for Life Sciences
2021
Tsinghua University
2021
Second Hospital of Anhui Medical University
2021
Anhui Medical University
2021
University Medical Centre Mannheim
2021
Heidelberg University
2021
University Hospital Heidelberg
2021
Zhangzhou Normal University
2010-2020
Maize employs complex mechanisms of gene regulation in response to drought stress. Micro‐RNAs (miRNAs) have emerged as a novel regulatory mechanism expression. Drought induces upregulation and downregulation numerous genes. However, little is known about the role miRNAs maize response. In this research, miRNA microarray hybridization showed that 34 from 13 plant families had significantly altered expression after treatment. Most miRNA‐mediated target genes contained cis‐acting element...
Summary Although hundreds of genetic male sterility ( GMS ) mutants have been identified in maize, few are commercially used due to a lack effective methods produce large quantities pure male‐sterile seeds. Here, we develop multicontrol MCS system based on the maize 7 ms7 mutant and its wild‐type Zea mays Male ZmMs7 gene via transgenic strategy, leading utilization hybrid seed production. is isolated by map‐based cloning approach encodes PHD ‐finger transcription factor orthologous rice PTC...
Understanding the molecular basis of male sterility and developing practical male-sterility systems are essential for heterosis utilization commercial hybrid seed production in crops. Here, we report regulation by genic gene maize 7 (ZmMs7) its application a dominant system multiple species. ZmMs7 is specifically expressed anthers, encodes plant homeodomain (PHD) finger protein that functions as transcriptional activator, plays key role tapetal development pollen exine formation. can...
Kiwifruit (Actinidia spp.) is a dioecious plant with fruits containing abundant vitamin C and minerals. A handful of kiwifruit species have been domesticated, among which Actinidiaeriantha increasingly favored in breeding owing to its superior commercial traits. Recently, elite cultivars from A. eriantha successfully selected further studies on their biology potential require genomic information, currently unavailable.We assembled chromosome-scale genome sequence cultivar White using...
Because of its significance for plant male fertility and, hence, direct impact on crop yield, pollen exine development has inspired decades scientific inquiry. However, the molecular mechanism underlying formation and thickness remains elusive. In this study, we identified that a previously unrecognized repressor, ZmMS1/ZmLBD30, controls proper in maize. Using an ms1 mutant with aberrantly thickened exine, cloned male-sterility gene, ZmMs1, which encodes tapetum-specific lateral organ...
Computational and experimental studies were applied to the discovery of a series novel vascular endothelial growth factor receptor 2 (VEGFR-2) inhibitors. Eight compounds exhibited nanomolar IC50 values against VEGFR-2, 6, 19, 22, 23 showed potent antiproliferative effects several cell lines. Particularly, compound behaved better than FDA approved drugs, sorafenib sunitinib, in activity lines related all nine tumor types tested (GI50 values), it was or comparable safety (LC50 values)....
Map-based cloning of maize ms33 gene showed that ZmMs33 encodes a sn-2 glycerol-3-phosphate acyltransferase, the ortholog rice OsGPAT3, and it is essential for male fertility in maize. Genetic sterility has been widely studied its biological significance commercial value hybrid seed production. Although many male-sterile mutants have identified (Zea mays L.), likely most genes cause are unknown. Here, we report recessive genetic mutant, sterility33 (ms33), which displays small, pale yellow...
Genic male sterility (GMS) is critical for heterosis utilization and hybrid seed production. Although GMS mutants genes have been studied extensively in plants, it has remained unclear whether chloroplast-associated photosynthetic metabolic activities are involved the regulation of anther development. In this study, we characterized function ZmMs33/ZmGPAT6, which encodes a member glycerol-3-phosphate acyltransferase (GPAT) family that catalyzes first step glycerolipid synthetic pathway. We...
Antibiotic-resistant bacteria are a great threat to human health and food safety there is an urgent need understand the mechanisms of resistance for combating these bacteria. In current study, comparative proteomic methodologies were applied identify Escherichia coli K-12 outer membrane (OM) proteins related kanamycin resistance. Mass spectrometry western blotting results revealed that OM TolC, Tsx OstA up-regulated, whereas MipA, OmpA, FadL OmpW down-regulated in kanamycin-resistant E....
Virus-induced gene silencing (VIGS) is a versatile and attractive approach for functional characterization in plants. Although several VIGS vectors maize (Zea mays) have been previously developed, their utilities are limited due to low viral infection efficiency, insert instability, short maintenance of silencing, inadequate inoculation method, or abnormal requirement growth temperature. Here, we established Cucumber mosaic virus (CMV)-based system efficient that overcomes many limitations...
N6-methyladenosine (m6A) plays a critical role in the tumorigenesis of cervical cancer (CC). Here, we aimed to investigate potential methyltransferase-like 3 (METTL3) CC. Gene expression was determined via real-time quantitative polymerase chain reaction. Cellular functions were detected using colony formation, 5-ethynyl-2'-deoxyuridine (EdU), and Transwell assays. The interactions among METTL3, insulin-like growth factor 2 mRNA-binding protein (IGF2BP3), apoptotic chromatin condensation...
Abstract A successful marker‐assisted selection (MAS)‐derived line should express new characteristics derived from the donor, and have a small number of donor chromosomal fragments. Different strategies can result in different proportion residual background within improved line. The effects on phenotype combining ability mostly remain unknown. In this study, waxy ( wx ) restorer gene Rf3 S‐type cytoplasm sterility were selected as model for MAS breeding by three strategies, to develop...
A new 3,4-seco-lupane triterpene, named sessiligenin (1), along with four known triterpene derivatives (chiisanogenin 2, chiisanoside 3, divaroside 4, and sessiliside-A1 5) were isolated from the ethanol extract of leaves Eleutherococcus sessiliflorus (Rupr. & Maxim.) S.Y. Hu by silica gel column chromatography, their structures determined spectroscopic data. Furthermore, all these compounds tested for cytotoxicities against cancer cell lines HepG2, B16-F10, Lewis YAC-1, as well normal...
Although the vasoactive properties of carbon monoxide (CO) have been extensively studied, mechanism by which CO mediates vasodilation is not completely understood. Through-out published studies on mediated there inconsistency type K + -channels that are activated releasing molecules (CORMs). Since vasorelaxation enzyme triggered CORMs (ET-CORMs) studied thus far, we first assessed if ET-CORMs can mediate small mesenteric arteries and subsequently addressed role soluble guanylate cyclase...