- Remote Sensing and Land Use
- Environmental Changes in China
- Anaerobic Digestion and Biogas Production
- Land Use and Ecosystem Services
- Forest Insect Ecology and Management
- Microbial Fuel Cells and Bioremediation
- Metabolism, Diabetes, and Cancer
- Natural product bioactivities and synthesis
- Diabetes Treatment and Management
- Cancer Immunotherapy and Biomarkers
- Soil erosion and sediment transport
- Phytochemical compounds biological activities
- Environmental and Agricultural Sciences
- Parasite Biology and Host Interactions
- Insect and Arachnid Ecology and Behavior
- Environmental remediation with nanomaterials
- Graphene research and applications
- Insect-Plant Interactions and Control
- Insect Pest Control Strategies
- Lung Cancer Treatments and Mutations
- Soil Geostatistics and Mapping
- Genetic Mapping and Diversity in Plants and Animals
- Carbon Nanotubes in Composites
- Insect symbiosis and bacterial influences
- Rice Cultivation and Yield Improvement
Chinese Academy of Sciences
2014-2025
Dalian University of Technology
2025
China Medical University
2025
Liaoning Cancer Hospital & Institute
2025
Institute of Zoology
2017-2024
Bioscience (China)
2024
KU Leuven
2024
Beijing Normal University
2024
University of Chinese Academy of Sciences
2011-2023
Shanghai Ocean University
2023
Despite the success of immune checkpoint blockade against melanoma, many "cold" tumors like prostate cancer remain unresponsive. We found that hypoxic zones were prevalent across preclinical and resisted T cell infiltration even in context CTLA-4 PD-1 blockade. demonstrated hypoxia-activated prodrug TH-302 reduces or eliminates hypoxia these tumors. Combination therapy with this hypoxia-prodrug cooperated to cure more than 80% transgenic adenocarcinoma mouse prostate-derived (TRAMP-derived)...
Anaerobic digestion (AD) is one of the most widely used bioconversion technologies for renewable energy production from wet biowaste.However, such AD system so complicated that it challenging to fully comprehend this process and design operational conditions a specific biowaste achieve CH4-rich biogas.In context, ensemble machine learning (ML) algorithms were employed develop multi-task models jointly predicting CH4 yield content in biogas understanding process.Based on best model with R 2...
A highly selective long-wavelength fluorescent probe TCFB has been developed for the detection of hCE2. The can be used real-time monitoring hCE2 activity in complex biological systems.
Summary African cultivated rice ( Oryza glaberrima Steud.) was domesticated from its wild progenitor species barthii ) about 3000 years ago. Seed shattering is one of the main constraints on grain production in rice, which causes severe losses during harvest. By contrast, Asian sativa displays greater resistance to seed shattering, allowing higher production. A better understanding regulation would help improve harvesting efficiency rice. Here, we report map‐based cloning and...
Intrauterine adhesion (IUA), characterized by endometrial fibrosis, may lead to infertility and recurrent pregnancy loss. At present, there is no ideal therapy for IUA. Recent findings have revealed that microRNAs (miRNAs) a decisive role in the regulation of fibrosis. The aim present study was investigate molecular mechanism miRNAs compared expression profiles between tissues from patients with IUA normal using microarray analysis. Validation miR‑326 level performed reverse...
Abstract Background Survival to cold stress in insects living temperate environments requires the deployment of strategies that lead physiological changes involved freeze tolerance or avoidance. These may consist of, for instance, induction metabolic depression, accumulation cryoprotectants, production antifreeze proteins, however, little is known about way such mechanisms are regulated and signals their activation. Ascarosides signaling molecules usually regulate nematode behavior...
<title>Abstract</title> Global plantations, crucial for restoring degraded landscapes, face rising invasive pest threats, in recent decades. This study highlights that the invasion and proliferation of fall webworm have been facilitated by global afforestation boom last 80 years could pose a threat to all ecological projects until 2050. Since 1940, this polyphagous has spread 40 countries, following an <italic>S-</italic>curve pattern. The distribution is positively correlated with expansion...
Eight new limonoids with four different structural frameworks, including gedunin (1, 2), havanensin (3, 4), mexicanolide (5, 6), and methyl angolensate types (7, 8), together six known limonoids, were isolated from the leaves of Cipadessa baccifera. Compounds 2 5 exhibited moderate cytotoxicity against HL-60 cell line an IC50 value 20 μM.
Abstract Trichiliton A ( 1 ), a novel limonoid with an unprecedented bicyclo[5.2.1 4,10 ]decane motif in the tetranortriterpenoid core, has been isolated from leaves of Trichilia connaroides . Its structure and absolute configuration have elucidated by spectroscopic analysis computational methods. The biosynthetic pathway compound is discussed involves alternative new routine mexicanolide to phragmalin.
Symbiotic microorganisms are ubiquitous on the body surface or internal tissues of invertebrates, providing them with benefits. Developing symbiotic relationships requires synchronization developmental stages and physical proximity partners. Therefore, identification metabolites that coordinate reproduction partners is essential. This study demonstrates palmitoleic acid (C16: 1) coordinates bilateral propagation by regulating between invasive pinewood nematode (PWN) its newly associated...
During anaerobic treatment, several microorganisms mediate a series of reactions to convert reduced compounds (electron donors) into methane. Inhibitors such as long chain fatty acids (LCFAs) can affect microbial populations and decrease the treatment efficiency. The effects three C18 LCFAs on hydrogenotrophic methanogens in flocculated mixed culture were assessed this study. reaction half-life hydrogen versus time profiles used characterize inhibition process. values similar for controls...