A5073928389- Advanced biosensing and bioanalysis techniques
- Anodic Oxide Films and Nanostructures
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Nanopore and Nanochannel Transport Studies
- Biosensors and Analytical Detection
- Bacterial Identification and Susceptibility Testing
- RNA Interference and Gene Delivery
- Microfluidic and Bio-sensing Technologies
- Conducting polymers and applications
- Antimicrobial Resistance in Staphylococcus
- Analytical Methods in Pharmaceuticals
Universidad de Oviedo
2022-2024
Introduction: Nanoporous alumina membranes present a honeycomb-like structure characterized by two main parameters involved in their performance electrochemical immunosening: pore diameter and thickness. Although this first one has been deeply studied, the effect of thickness electrochemical-based nanopore immunosensors less taken into consideration. Methods: In work, influence nanoporous steric blockage is studied for time, through formation an immunocomplex inner walls. Finally, optimal...
The stochastic sensing based on single nanopores is considered as one of the more relevant breakthroughs in bioanalysis, rightly summarized previous reviews. Inspired by it, use solid-state nanochannel arrays has paved way to electrochemical systems whose detection principle different that sensing. In view growing interest and continuous research improvements this field, an update much needed. Moreover, great potential these for clinical diagnostics deserves a special focus. context, review...
Abstract Electrochemical immunosensors have emerged in the last years as outstanding analytical systems for detection of analytes clinical interest. As alternative to traditional enzymatic labels, use nanoparticles and especially bimetallic ones has gained increased attention thanks their advantages related higher simplicity, stability sensitivity offered. Main routes such nanoparticle labels are based on i) dissolution into corresponding metal ions followed by voltammetric detection; ii)...
Abstract For the first time use of nanoparticles as carriers an enzymatic substrate immobilized inside nanoporous alumina membranes is proposed with aim amplifying nanochannel blocking produced and, consequently, improving efficiency enzyme determination through cleavage. Streptavidin-modified polystyrene (PSNPs) are carrier agents, contributing to steric and electrostatic blockage due charge they present at different pH values. Electrostatic predominant effect that governs in interior...