A5008322451- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Advanced Nanomaterials in Catalysis
- Hearing, Cochlea, Tinnitus, Genetics
- HER2/EGFR in Cancer Research
- Nanoplatforms for cancer theranostics
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Breast Cancer Treatment Studies
- Radiopharmaceutical Chemistry and Applications
- Hearing Loss and Rehabilitation
- RNA modifications and cancer
- Circular RNAs in diseases
- Dermatologic Treatments and Research
- Marine animal studies overview
- Advanced Radiotherapy Techniques
- Nanoparticle-Based Drug Delivery
- Cancer Diagnosis and Treatment
Jiangnan University
2024
University of Electronic Science and Technology of China
2024
Harbin Medical University
2020-2023
Fourth Affiliated Hospital of Harbin Medical University
2020-2023
Zhongshan City Second People's Hospital
2014
Inefficient tumor accumulation and penetration remain as the main challenges to therapy efficacy of lung cancer. Local delivery smart nanoclusters can increase drug provide superior antitumor effects than systemic routes. Here, we report self-assembled pH-sensitive superparamagnetic iron oxide (SPIONCs) that enhance in situ ferroptosis apoptosis with radiotherapy chemodynamic therapy. After pulmonary orthotopic cancer, SPIONCs disintegrate into smaller nanoparticles release more ions an...
overexpression on the proliferation of KFs was assayed using EdU assay.Compared with mock-transfected cells, transfected a miR-199a-5p mimic showed significantly lower cell and an altered cycle, cells having longer S G2/M phases.The expression miRNA-199a-5p in keloids likely influences cycle restrains their proliferation, suggesting that probably plays role regulation KF proliferation.
This article has been retracted, and the online PDF replaced with this retraction notice.
Background The human epidermal growth factor receptor 2 gene (HER2) has been identified as a potential therapeutic target in lung adenocarcinoma (LUAD). Non-invasive positron emission tomography (PET) imaging provides reliable strategy for vivo determination of HER2 expression through whole-body detection abnormalities. PET tracer 68 Ga-NOTA-MAL-Cys-MZHER 2:342 shown promising results HER2-positive breast and gastric cancers. This study aims to evaluate the performance vitro models clinical...
Mammals suffer permanent hearing impairment from the loss of auditory hair cells due to their inability regenerate. In contrast, lower vertebrates exhibit extraordinary capacity for cell regeneration and restoration, but mechanisms remain unclear. Here we characterize single-cell atlas Xenopus laevis inner ear perform a comprehensive comparison with mouse model. An exceptionally conserved neuronal type is discovered. The results reveal that outer (OHCs) exist exclusively in mammals....
Background: Breast cancer is the most common malignant tumour in women. Radical mastectomy with postoperative radiotherapy now standard treatment for locally advanced breast cancer. Intensity-modulated (IMRT) has been developed, which employs linear accelerators to deliver precise radiation a while minimizing dose surrounding normal tissue. It significantly improves efficacy of treatment. However, there are still some flaws that must be addressed. Objective: To assess clinical application...