Lixin Chen

ORCID: 0009-0005-7802-332X
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About
Contact & Profiles
Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Advanced Radiotherapy Techniques
  • Renal cell carcinoma treatment
  • Cancer-related molecular mechanisms research
  • Cancer Genomics and Diagnostics
  • Acute Kidney Injury Research
  • Medical Imaging Techniques and Applications
  • BRCA gene mutations in cancer
  • Congenital Diaphragmatic Hernia Studies
  • Medical Research and Treatments
  • Influenza Virus Research Studies
  • Cardiovascular and Diving-Related Complications
  • Circular RNAs in diseases
  • Kidney Stones and Urolithiasis Treatments
  • Medical Imaging and Pathology Studies
  • Traumatic Brain Injury Research
  • Chronic Kidney Disease and Diabetes
  • Animal Virus Infections Studies
  • 14-3-3 protein interactions
  • Dialysis and Renal Disease Management
  • Cancer Immunotherapy and Biomarkers
  • Vitamin D Research Studies
  • Pharmacological Effects of Medicinal Plants
  • Vascular anomalies and interventions
  • Inflammasome and immune disorders

Tianjin Children's Hospital
2024

Peking Union Medical College Hospital
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Longhua Hospital Shanghai University of Traditional Chinese Medicine
2022-2024

Shanghai University of Traditional Chinese Medicine
2022-2024

Sichuan University
2021

West China Hospital of Sichuan University
2021

Jilin University
2021

Jinan University
2021

State Key Laboratory of Oncology in South China
2007

Persistent hypotonic and inflammatory conditions in the joint cavity can lead to loss of cartilage matrix cell death, which are important mechanisms osteoarthritis (OA) onset. Previous studies have confirmed that existence a environment is red flag for inflammation, as induces opening chloride channel promotes ion efflux, prompts volume increase. Chloride channels play an role regulation mineralization chondrocyte death. Here, we reported OA chondrocytes showed significant increase death...

10.1093/abbs/gmab010 article EN cc-by Acta Biochimica et Biophysica Sinica 2021-01-29

Background: Breast cancer (BC) is the leading cause of cancer-related deaths among women worldwide. The application advanced technology has promoted accurate diagnosis and treatment cancer. Anhydroicaritin (AHI) a flavonoid with therapeutic potential in BC treatment. current study aimed to determine AHI's mechanism via RNA sequencing, comprehensive bioinformatics analysis, experimental verification. Methods: Network pharmacology MTT (3-(4,5)-dimethylthiazolyl-3,5- diphenyltetrazolium...

10.3389/fcell.2021.764481 article EN cc-by Frontiers in Cell and Developmental Biology 2022-02-01

Ovarian cancer (OC) is the leading cause of death from gynecological cancer. In this study, we aimed to explore role and potential mechanism LIMD2 during progression OC. The expression was analyzed by GEPIA (Gene Expression Profiling Interactive Analysis) database. Western blot real-time PCR were applied detect gene

10.1080/21655979.2021.2000732 article EN Bioengineered 2021-11-02

Objective: To observe the effects of dynamic pressure monitoring on lifespan extracorporeal circuit and efficiency solute removal during continuous renal replacement therapy (CRRT). Materials Methods: A prospective observational study was performed at West China Hospital Sichuan University in ICU. Analyses downloaded data recorded by CRRT machines efficiencies, calculated 2 * Ce/(Cpre+Cpost), where Ce, Cpre, Cpost are concentrations effluent, pre-filter blood, post-filter respectively, were...

10.3389/fmed.2021.621921 article EN cc-by Frontiers in Medicine 2021-09-23

Increasing reports revealed that circular RNAs (circRNAs) and immune cells infiltration were related with tumor development. However, its role in infantile hemangioma (IH) is unknown. We will explore a novel hsa_circ_0006903-based ceRNA network investigate the landscape of dendritic activated expression IH.

10.1016/j.heliyon.2024.e34186 article EN cc-by-nc Heliyon 2024-07-01

Objective To investigate the effect of controlling blood pressure in treating patients with hypertension by taking quantitative vitamin D to provide support for clinical treatment hypertension. Methods 100 cases were randomly divided into two groups voluntarily,50 each group and one a simple standard was considered as control group, other study 25μg/d taken besides treatment.Each content 25 - hydroxyvitamin D[25(OH)D]level measured Enzyme- linked immunosorbent assay(ELISA)and lasted...

10.3760/cma.j.issn.1008-6706.2015.01.017 article EN Zhongguo jiceng yiyao 2015-01-01
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