A5002100786- Inflammasome and immune disorders
- Psoriasis: Treatment and Pathogenesis
- Retinoids in leukemia and cellular processes
- IL-33, ST2, and ILC Pathways
- Cytokine Signaling Pathways and Interactions
- Atherosclerosis and Cardiovascular Diseases
Semmelweis University
2023-2024
Abstract Immune‐mediated inflammatory disease (IMID) patients including psoriasis, arthritides and bowel diseases have a higher risk of developing cardiovascular (CV) compared to the general population. The increased CV may be promoted by tumour necrosis factor (TNF)‐α‐mediated immunological processes, which are present both in pathomechanism IMIDs atherosclerosis. Our objective was comprehensively investigate effect TNF inhibitors (TNFi) on with conventional therapies IMIDs. systematic...
The systemic nature of the inflammatory processes in psoriasis is now widely accepted. It known that IL-23/ Th-17 axis plays a pivotal role development skin and joint symptoms, which immune overlap with pathways involved pathogenesis cardiometabolic comorbidities at several points. IL-17 inhibitor biological therapies are frontline treatments for moderate-to-severe have also been focus interest recent years because their potential effects on comorbidities. In this review we aim to describe...