A5018107754- CAR-T cell therapy research
- Poverty, Education, and Child Welfare
- Semiconductor Quantum Structures and Devices
- Corporate Finance and Governance
- Income, Poverty, and Inequality
- Cooperative Studies and Economics
- Photonic and Optical Devices
- Semiconductor Lasers and Optical Devices
- Fiscal Policy and Economic Growth
- Pregnancy and preeclampsia studies
- Agricultural risk and resilience
- Malaria Research and Control
- Agricultural Innovations and Practices
- Mosquito-borne diseases and control
- Colorectal Cancer Screening and Detection
- Gender, Labor, and Family Dynamics
- Microfinance and Financial Inclusion
- Labor Movements and Unions
- International Development and Aid
- Water resources management and optimization
- Genetically Modified Organisms Research
- Economic Growth and Productivity
- Taxation and Compliance Studies
- Innovation and Socioeconomic Development
- Genetic Mapping and Diversity in Plants and Animals
Caribou Biosciences (United States)
2019-2024
Wake Forest University
2022
George Washington University
2011-2021
Centers for Disease Control and Prevention
2007-2021
Division of Parasitic Diseases and Malaria
2014-2021
Hospital of St. Cross
2012-2021
Center for Global Health
2016-2021
University Hospitals Coventry and Warwickshire NHS Trust
2003-2020
Abington Memorial Hospital
2020
Queen's Medical Centre
2020
Background An organized, population-based, colorectal cancer screening programme was initiated in England 2006 offering biennial faecal occult blood testing (FOBT) to adults aged 60–69 years. Organized programmes with no associated financial costs the individual should minimize barriers access for lower socio-economic status (SES) groups. However, SES differences uptake were observed pilot centres of UK programme, so aim this analysis identify extent inequalities by SES, ethnic diversity,...
Chronic diarrhoea is a common problem, hence clear guidance on investigations required. This an updated guideline from 2003 for the of chronic commissioned by Clinical Services and Standards Committee British Society Gastroenterology (BSG). document has undergone significant revision in content through input 13 members Guideline Development Group (GDG) representing various institutions. The GRADE system was used to appraise quality evidence grading recommendations.
Cardiac troponin T (cTnT), measurement of which has been recommended for diagnosing myocardial infarction, was initially believed to be specific the heart. However, recent publications have reported cTnT in sera patients without cardiac disease; therefore, we investigated whether could found human skeletal muscle tissues. Using immunohistochemistry, Western blot, and quantitative ELISA, assayed heart (n = 3), normal 6), diseased samples from with polymyositis (PM, n 13) Duchenne muscular...
Abstract We evaluate causal impacts of a large‐scale agricultural extension program for smallholder women farmers on technology adoption and food security in Uganda through regression discontinuity design that exploits an arbitrary distance‐to‐branch threshold village eligibility. find eligible used better basic cultivation methods, achieved improved security. Given minimal changes relatively expensive inputs, we attribute these gains to methods require low upfront monetary investment....
Plant breeders require genetic diversity to develop cultivars that are productive, nutritious, tolerant of biotic and abiotic stresses, make efficient use water fertilizer. The USDA‐ARS National Germplasm System (NPGS) is a major source for global plant resources (PGR), with accessions representing improved cultivars, breeding lines, landraces, crop wild relatives (CWR), coupled passport trait evaluation data. goal this article facilitate PGR in programs. Our specific objectives (i)...
Allogeneic chimeric antigen receptor (CAR) T cell therapies hold the potential to overcome many of challenges associated with patient-derived (autologous) CAR cells. Key considerations in development allogeneic include prevention graft-vs-host disease (GvHD) and suppression allograft rejection. Here, we describe preclinical data supporting ongoing first-in-human clinical study, CaMMouflage trial (NCT05722418), evaluating CB-011 patients relapsed/refractory multiple myeloma. is a...
The authors analyze the differences between behavior of private firms and that producer cooperatives in a matched sample two organizational types from regions Emilia Romagna Toscana North-Central Italy, where are numerous. Individual firm-level surveys provide new detailed comparative data on key issues such as investment, productivity, wages, employment, industrial relations. Differences firm found labor relations, pay, production methods, relationship to external market environment, level...
The paper examines the microeconomic (partial equilibrium) behavior of joint ventures established between transnational corporations and domestic partners in less developed countries. It focuses on issues relating to resource allocation profit distribution under various institutional scenarios. analysis places special emphasis role bargaining power, transfer pricing, stock ownership, shares parties, responsiveness national development goals. Some results apply wholly owned subsidiaries...
ABSTRACT The objectives of this study were to (i) measure genetic gain using a set maize ( Zea mays L.) single‐cross hybrids that widely used in Chinese production from 1964 2001, (ii) determine if there changes morphological characteristics, and (iii) examine the germplasm backgrounds these hybrids. Yield trials conducted for 3 yr, split‐plot design. Each hybrid was planted at three different densities four locations, two locations each representing summer spring corn areas. Mean rates 52...
A key goal of malaria control is to achieve universal access to, and use of, long-lasting insecticidal nets (LLINs) among people at risk for malaria. Quantifying the number LLINs needed maintain coverage requires knowing when need replacement. Longitudinal studies have observed physical deterioration in well before assumed net lifespan 3 years. The objective this study was describe attrition, integrity insecticide persistence over time assist with better quantification needing...
Abstract Background Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs expected to last at least 3 years under normal use conditions, they can lose effectiveness because fall out use, discarded, repurposed, physically damaged, or activity. The contributions these different interrelated factors durability their protection against have been unclear. Methods Starting 2009, LLIN studies were...
Long-lasting insecticide treated nets (LLINs) and indoor residual house spraying (IRS) are the main interventions for control of malaria vectors in Zanzibar. The aim present study was to assess susceptibility status against insecticides used LLINs IRS determine durability efficacy on island.Mosquitoes were sampled from Pemba Unguja islands 2010-2011 use WHO tests. One hundred fifty collected households Unguja, their physical state recorded then tested as well total content.Species...
Significance Controlled degradation of specific proteins is used by all organisms to change cell behavior in response internal or external cues. Because ATP-dependent proteases, such as ClpXP, have a broad range targets, accessory called adaptors are often necessary for selective substrate proteolysis. Here we show that three work together multicomponent adaptor stimulate the key regulatory protein, CtrA, Caulobacter crescentus . The only functional when one components, CpdR,...
This article uses household panel data to provide robust evidence on the effects of BRAC's (Building Resources across Countries) Targeting Ultra-poor (TUP) program in Bangladesh. We use alternative treatment-comparison pairs; addition own classification, we exploit type 1 errors assignment selection process create a second pair. allows us estimate target group, not contaminated by mistargeting. To address unobservables, implement heteroskedasticity-based identification and two recent...
Bowel cancer is a serious health burden and its early diagnosis improves survival. The Cancer Screening Programme (BCSP) in England screens with the Faecal Occult Blood test (FOBt), followed by colonoscopy for individuals positive result. Socioeconomic inequalities have been demonstrated FOBt uptake, but it not known whether they persist at next stage of screening pathway. aim this study was to assess association between uptake area socioeconomic deprivation, controlling individual age sex,...