- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Conditions and Treatments
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Infrared Target Detection Methodologies
- Cardiovascular and exercise physiology
- ECG Monitoring and Analysis
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Advanced X-ray and CT Imaging
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Muscle activation and electromyography studies
- Remote Sensing and LiDAR Applications
- Aortic Disease and Treatment Approaches
Bethesda North Hospital
2024
TriHealth
2024
Abbott (United States)
2020-2024
Abbott (Canada)
2023
Cedars-Sinai Medical Center
2013-2023
Sinai Hospital
2023
Abbott (Sweden)
2007-2022
St. Jude Medical Center
2007-2015
Memorial Medical Center
1985-2010
Christchurch Clinical Studies Trust
2007
Abstract Objectives Characterize the safety and effectiveness of Amplatzer Piccolo Occluder for patent ductus arteriosus (PDA) closure. Background The presence a hemodynamically significant PDA has been associated with an increased risk morbidity mortality in children born premature. Methods This was single arm, prospective, multicenter, non‐randomized study to evaluate treat patients ≥700 g. From June 2017 February 2019, 200 were enrolled at nine centers, 100 weighing ≤2 kg. Primary...
This study describes 3-year follow-up of 200 infants weighing ≥ 700 grams who underwent transcatheter patent ductus arteriosus (PDA) closure with the Amplatzer Piccolo™ Occluder.Between June 2017 and February 2019, children were enrolled in this U.S. (NCT03055858). PDA closure, survival, device- or procedure-related events evaluated. A total 156 available 182 patients (86%) completed study.The implant success rate was 95.5% (191/200). At 3 years, observed 100% (33/33) patients. Survival >95%...
A postinfarct ventricular septal defect (PIVSD) is associated with high mortality and morbidity, particularly in patients hemodynamic instability who are not suitable candidates for surgical repair. The Amplatzer PIVSD Occluder (Abbott) indicated transcatheter closure satisfactory objective of this study was to evaluate clinical outcomes.
The production of robust classifiers by combining supervised training with unsupervised is discussed. A phase exploits statistically scene invariant labeled data to produce an initial classifier. This followed that clustering properties unlabeled data. two-phase process termed mixed adaptation. probabilistic model supporting this technique presented along examples illustrating These include the detection unspecified dotted curves in noise and classification vehicles cinematic sequences...
The purpose of this report is to show results automatic target classification and sensor fusion for forward looking infrared (FLIR) Laser Radar sensors. data base was acquired from the Naval Weapon Center it consists coregistered RaDAR (range reflectance image), FLIR (raw preprocessed image) TV. Using we have developed techniques extract relevant object edges LADAR which are correlated wireframe models. resulting correlation coefficients both fused using either Bayesian or Dempster-Shafer...
Monitoring of HF (heart failure) with intracardiac pressure, intrathoracic impedance and/or natriuretic peptide levels has been advocated. We aimed to investigate possible differences in the response patterns each these monitoring modalities during decompensation that may have an impact on potential for early therapeutic intervention. Six sheep were implanted a LAP (left atrial pressure) sensor and CRT-D (cardiac resynchronization therapy defibrillator) capable along six lead configuration...
The safety and efficacy of an implantable left atrial pressure (LAP) monitoring system is being evaluated in a clinical trial setting. Because the number available specimens from for histopathology analysis limited, it beneficial to maximize usage each specimen by relying on integrated microscopy techniques. aim this study demonstrate how comprehensive pathology single may be reliably achieved using Integrated techniques consisting high-resolution gross digital photography followed...
Introduction: We investigated trends in intrathoracic impedance measured between multiple implanted electrodes for monitoring pulmonary edema secondary to congestive heart failure (CHF) an experimental model. Methods: Biventricular ICDs were 16 dogs and 5 sheep. Continuous RV pacing (230–250 bpm) was applied over several weeks. Meanwhile, every hour along 4 2 intracardiac vectors. Four cardiogenic vectors also monitored. Cardiac function assessed biweekly by catheterization echocardiography....
Rapid recovery protocols for coronary artery bypass grafting (CABG) have resulted in major decreases postoperative hospital length of stay (LOS) when applied to younger patients undergoing elective procedures. However, the effectiveness rapid octogenarians has not been thoroughly studied.Thirty-seven consecutive underwent isolated CABG utilizing cardiopulmonary (CPB). A protocol emphasizing preoperative placement intra-aortic balloon pump, reduced CPB time, early extubation, perioperative...
Atrial fibrillation (AFIB) is the most common complication following coronary artery bypass grafting (CABG). Despite three decades of recognition, efforts to reduce high incidence reported (15%-30%) have been largely unsuccessful. Reasons for postoperative AFIB are likely multifactorial. As a result, we defined multidrug prophylaxis based on agents known be individually effective. This method was applied prospectively series consecutive CABG patients with goal reducing new-onset...
Background We hypothesized that left atrial pressure (LAP) obtained by a permanent implantable sensor is sensitive to changes in cardiac resynchronization therapy (CRT) settings and could guide CRT optimization improve the response rate. investigated effect of on LAP its waveform parameters ambulant heart failure (HF) patients. Methods was performed eight HF patients, using echocardiography as reference. acquired at each atrioventricular (AV) intervals five inter‐ventricular (VV) intervals....
Background An implantable left atrial pressure (LAP) monitoring system for guiding the management of patients with advanced heart failure has potential to require extraction, particularly in setting infection. The LAP sensor lead was designed be suitable ease percutaneous extraction using standard techniques extracting pacemaker and defibrillator leads. clinical experience, date, is presented. Methods A total 82 underwent successful implantation transseptal catheterization. Five during a...
The rationale for intrathoracic impedance (Z) detection of worsening heart failure (HF) presupposes that changes in Z reflect pulmonary congestion, but is confounded by poor specificity clinical trials. We therefore tested the hypothesis primarily affected tissue/water content proximity to electrodes rather than lung water distribution between through use a new computational model deriving near-field contributions from various electrodes. Six sheep were implanted with left atrial pressure...
ObjectiveBioprosthetic surgical aortic valve replacement remains an important treatment option in the era of transcatheter interventions. Real-world outcomes are not well characterized because limited prospective follow-up studies. We present 10-year clinical Medicare beneficiaries undergoing with a contemporary supra-annular porcine valve.MethodsThis is single-arm observational study using fee-for-service claims data. De-identified patients Epic Supra (Abbott) United States between January...
A left atrial pressure (LAP) monitoring system was developed for guiding the management of patients with heart failure. The LAP sensor is implanted into atrium via transseptal catheterization and affixed to interatrial septum by nitinol anchors. long-term safety permanent implantation in evaluated based on comparative pathology animals. Tissue specimens from 7 patients, 49 canines, 14 ovine were examined thrombosis tissue overgrowth. Implant duration ranged 22 1,686 days. Gross examination...