A5086004340- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiovascular Conditions and Treatments
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular and Diving-Related Complications
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- COVID-19 and healthcare impacts
- Aortic aneurysm repair treatments
- Vascular anomalies and interventions
- Transplantation: Methods and Outcomes
- Cardiovascular Issues in Pregnancy
- Cardiac pacing and defibrillation studies
- Healthcare cost, quality, practices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Coronary Interventions and Diagnostics
- Tracheal and airway disorders
- Coenzyme Q10 studies and effects
- Neonatal Respiratory Health Research
- Cardiac tumors and thrombi
Seattle Children's Hospital
2016-2025
University of Washington
2017-2024
Children's Healthcare of Atlanta
2017
Emory University
2017
Lucile Packard Children's Hospital
2016
Boston Children's Hospital
2013-2016
Miami Children's Hospital
2013
Nationwide Children's Hospital
2013
University of Rochester
2007
University of Rochester Medical Center
2006
Background— The Melody transcatheter pulmonary valve (TPV) was approved for implantation in obstructed right ventricular outflow tract conduits 2010 after a multicenter trial demonstrating improvements conduit obstruction, regurgitation, and pressure. A recognized risk contraindication to TPV is the demonstration of coronary artery (CA) compression during balloon angioplasty or stent placement overlying conduit. This study first characterize CA this population. Methods Results— From 2007...
Abstract Objectives Characterize the safety and effectiveness of Amplatzer Piccolo Occluder for patent ductus arteriosus (PDA) closure. Background The presence a hemodynamically significant PDA has been associated with an increased risk morbidity mortality in children born premature. Methods This was single arm, prospective, multicenter, non‐randomized study to evaluate treat patients ≥700 g. From June 2017 February 2019, 200 were enrolled at nine centers, 100 weighing ≤2 kg. Primary...
This study describes 3-year follow-up of 200 infants weighing ≥ 700 grams who underwent transcatheter patent ductus arteriosus (PDA) closure with the Amplatzer Piccolo™ Occluder.Between June 2017 and February 2019, children were enrolled in this U.S. (NCT03055858). PDA closure, survival, device- or procedure-related events evaluated. A total 156 available 182 patients (86%) completed study.The implant success rate was 95.5% (191/200). At 3 years, observed 100% (33/33) patients. Survival >95%...
Background: Percutaneous transcatheter pulmonary valve replacement (TPVR) has good clinical and hemodynamic outcomes in treating dysfunctional bioprosthetic valves (BPV) the position. Valve-in-valve therapy can further decrease inner diameter (ID), potentially resulting patient-prosthesis mismatch patients with smaller BPVs. Methods Results: To evaluate feasibility of intentional BPV fracture to enlarge orifice TPVR, 37 from 13 centers who underwent TPVR intended were evaluated. A control...
Objectives The objective was to review the use of Impella devices (Abiomed Inc, Danvers, MA) for temporary circulatory support in pediatric and adolescent patients (age ≤ 21 yrs). Background Options minimally invasive children are limited, published data confined case reports small series. Methods This a retrospective, multicenter implants from 2009‐15, using standardized collection INTERMACS definitions. Results A total 39 were performed 38 16 centers. Median age weight yrs (4–21 yrs) 62 kg...
Treatment with endovascular stents has become increasingly common for the management of vascular stenosis in congenital heart disease. The use smaller patients been tempered by concerns about potential stent expansion to accommodate somatic growth. One solution limited diameter is intentional fracture maximally dilated stents, which can be accomplished using ultra-high-pressure (UHP) balloons.This retrospective cohort study compared procedural characteristics and adverse events between a...
Follow-up of transcatheter pulmonary valve replacement (TPVR) with the Melody has demonstrated good short-term and long-term outcomes, but there are no published studies focused on performance in Contegra bovine jugular vein conduit.This is a retrospective, multicenter study short- intermediate-term outcomes TPVR within conduit right ventricle to artery position. Data from 13 centers were included analysis. During period, 136 patients underwent 139 catheterizations for attempted median...
Background There are limited mechanical circulatory support options for patients with single ventricle (SV) anatomy. This is a multicenter, retrospective study of the Impella pump to systemic in cohort SV Fontan circulation. Methods Patients anatomy supported an device from 2012 2015 were included. Demographic information, indication support, adverse events and short‐term outcome data collected. Results Ten The median age weight at implant was 26 years (4‐38 years) 64 kg (15–102 kg)....
Abstract Background Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become reality. However, predicting secure, atraumatic implantation catheter‐based device remains significant challenge due the complex dynamic nature right ventricular (RVOT). We sought quantify differences compression volume for actual implants, those predicted by...
Abstract Objective To assess the outcomes of use percutaneous Impella RP device (Abiomed, Danvers, MA) in adolescents and young adults. Background Results have been reported adults, but a multicenter experience adults has yet to be reported. Methods Patients ≤21 years age who underwent implantation an for refractory right heart failure from June, 2016 April, 2018 at nine U.S. Centers were included. A total 12 adolescents, median 18 (14–21) weight 74.4 (49–112.4) kg (INTERMACS Profile 1 2...
BACKGROUND: Anatomic selection for Harmony valve implant is determined with the aid of a screening report and perimeter plot (PP) that depicts perimeter-derived radius along right ventricular outflow tract (RVOT) projects device oversizing. The PP provides an estimation suitability implant, but its sensitivity as method unknown. This study was performed to describe anatomic features outcomes in patients who underwent TPV25 despite predicted inadequate METHODS: We reviewed RVOT measurements...
Abstract Background Stent implantation has become standard of care in older children and adults for treatment branch pulmonary artery stenosis (BPAS) coarctation aorta (CoAo). There are no stents approved or available infants that have the potential to be dilated adult diameters. The Minima stent was designed fulfill this unmet need. Methods Multicenter, prospective, nonrandomized early feasibility study evaluating safety effectiveness BPAS CoAo. Primary endpoints included: (1) successful...