Clément Karsenty

ORCID: 0000-0002-3303-5854
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Cardiac Valve Diseases and Treatments
  • Cardiac Arrhythmias and Treatments
  • Pulmonary Hypertension Research and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Aortic Disease and Treatment Approaches
  • Cardiovascular and Diving-Related Complications
  • Cardiac Structural Anomalies and Repair
  • COVID-19 Clinical Research Studies
  • Mechanical Circulatory Support Devices
  • Cardiac pacing and defibrillation studies
  • Anatomy and Medical Technology
  • Atrial Fibrillation Management and Outcomes
  • Coronary Artery Anomalies
  • Surgical Simulation and Training
  • Cardiac electrophysiology and arrhythmias
  • Tracheal and airway disorders
  • Congenital heart defects research
  • Vascular anomalies and interventions
  • Heart Failure Treatment and Management
  • Cardiomyopathy and Myosin Studies
  • COVID-19 and healthcare impacts
  • Ultrasound in Clinical Applications
  • Radiation Dose and Imaging

Institut des Maladies Métaboliques et Cardiovasculaires
2016-2025

Inserm
2016-2025

Université de Toulouse
2015-2025

Centre Hospitalier Universitaire de Toulouse
2016-2025

Clinique Pasteur
2022-2025

Université Toulouse III - Paul Sabatier
2016-2024

Hôpital des Enfants
2015-2024

Hôpital Européen Georges-Pompidou
2017-2023

Hôpital Européen
2017-2023

Université Paris-Saclay
2021-2023

Ventricular arrhythmias and sudden death are recognized complications in tetralogy of Fallot. Electrophysiological studies (EPS) before pulmonary valve replacement (PVR), the most common reintervention Fallot, could potentially inform therapy to improve arrhythmic outcomes.A prospective multicenter study was conducted systematically assess EPS with programmed ventricular stimulation patients Fallot referred for PVR from January 2020 December 2021. A standardized protocol used across all...

10.1161/circep.122.011745 article EN Circulation Arrhythmia and Electrophysiology 2023-05-12

Abstract Background Three-dimensional (3D) printing technology enables the translation of 2-dimensional (2D) medical imaging into a physical replica patient’s individual anatomy and may enhance understanding congenital heart defects (CHD). We aimed to evaluate usefulness spectrum 3D-printed models in teaching CHD students. Results performed prospective, randomized educational procedure teach fifth year students four CHDs (atrial septal defect (ASD, n = 74), ventricular (VSD, 50), coarctation...

10.1186/s12909-021-02917-z article EN cc-by BMC Medical Education 2021-09-08

Abstract Aims While some concerns about vaccination-related pericarditis and/or myocarditis have been raised, no published data are available on with mRNA COVID-19 vaccines in the age group of adolescents, particularly 12–15 years. The objective this study was to determine whether risk reporting varied according dose vaccination, age, sex, and type adolescents between 12 17 Methods results We performed an observational reviewing all reports vaccinated recorded VigiBase®, World Health...

10.1093/ehjqcco/qcab090 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2021-11-23

Abstract Background and Aims Transcatheter pulmonary valve implantation (TPVI) is indicated to treat right-ventricular outflow tract (RVOT) dysfunction related congenital heart disease (CHD). Outcomes of TPVI with the SAPIEN 3 that are insufficiently documented were investigated in EUROPULMS3 registry 3-TPVI. Methods Patient-related, procedural, follow-up outcome data retrospectively assessed this observational cohort from 35 centres 15 countries. Results Data for 840 consecutive patients...

10.1093/eurheartj/ehad663 article EN European Heart Journal 2023-10-24

Accurately imaging adult cardiac tissue in its native state is essential for regenerative medicine and understanding heart disease. Current fluorescence methods encounter challenges with fixation. Here, we introduce the 3D-NaissI (3D-Native Tissue Imaging) method, which enables rapid, cost-effective of fresh samples their closest state, has been extended to other tissues. We validated efficacy preserving integrity using small biopsies under hypothermic conditions phosphate-buffered saline,...

10.1007/s00018-025-05595-y article EN cc-by-nc-nd Cellular and Molecular Life Sciences 2025-02-05

The Lifetech KONAR-MF ventricular septal defect occluder (MFO) is increasingly used for transcatheter perimembranous (pmVSD) closure. We aim to collect real-world data on patient outcomes and MFO performance in pmVSD cases. This was a nonrandomized, retrospective, multicenter, postmarketing clinical follow-up study of patients implanted with the device between 2018 2023. primary endpoint 6-month composite success, defined as technical success (successful implantation retention at end...

10.1016/j.rec.2025.02.010 article EN cc-by Revista Española de Cardiología (English Edition) 2025-03-01

Abstract Background and Aims The natural history of congenital or childhood non-immune, isolated atrioventricular block (AVB) is poorly defined. We aimed at clarifying its long-term outcomes. Methods retrospectively studied 385 children with isolated, non-immune AVB diagnosed from in utero up to 18 years age, 29 French medical centers, between 1980 2022. Patients structural heart disease, endomyocardial fibrosis maternal antibodies were excluded. Results was asymptomatic 314 (81.6%) complete...

10.1093/europace/euaf040 article EN cc-by EP Europace 2025-03-11

Abstract Aims Although cardiac involvement has prognostic significance in coronavirus disease 2019 (COVID-19) and is associated with severe forms, few studies have explored the role of transthoracic echocardiography (TTE). We investigated link between TTE parameters prognosis COVID-19. Methods results Consecutive patients COVID-19 admitted to 24 French hospitals were retrospectively included. Comprehensive data, including clinical biological parameters, recorded at admission. Focused was...

10.1093/ehjci/jeab067 article EN other-oa European Heart Journal - Cardiovascular Imaging 2021-03-30

This study sought to investigate patient intermediate-term outcomes after transcatheter pulmonary valve replacement (TPVR) with Edwards SAPIEN valve.The valve, initially designed for percutaneous aortic replacement, has been approved TPVR in patients dysfunctional right ventricular outflow tracts (RVOT), but only short-term follow-up reported.From 2011 2016, 62 undergoing successful using the XT were consecutively included into study. Primary efficacy and safety endpoints defined as freedom...

10.1002/ccd.29862 article EN Catheterization and Cardiovascular Interventions 2021-07-06

The European Society of Cardiology (ESC) EURObservational Research Programme (EORP)-Atrial Fibrillation (AF) III Registry aims to identify contemporary patterns in AF management clinical practice, assess their compliance with the 2016 ESC Guidelines, major gaps guideline implementation, characterize practice settings associated good vs. poor implementation and compare 1-year outcome guideline-adherent non-adherent strategies. Consecutive adult patients (n = 8306) were enrolled between 1 July...

10.1093/ehjqcco/qcaa050 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2020-06-02

Paediatric interventional catheterisation has consistently improved in recent decades, with often highly successful outcomes. However, progress is still required terms of the information delivered to parents and how parental anxiety managed.

10.3389/fped.2022.947340 article EN cc-by Frontiers in Pediatrics 2023-01-09

<h3>Objectives</h3> To evaluate bare-metal Optimus and polytetrafluoroethylene (PTFE)-covered Optimus-CVS balloon-expandable, cobalt–chromium, hybrid cell–designed stents in congenital heart disease (CHD) interventions. <h3>Methods</h3> Retrospective multicentre review of patients with CHD receiving stents. Stent mechanical behaviour, clinical indications outcomes were assessed. <h3>Results</h3> 183 (49.2% XXL/15-ZIG, 33.3% XL/12-ZIG, 17.5% L/9-ZIG) implanted (98.9% success rate, 2.3%...

10.1136/openhrt-2022-002157 article EN cc-by-nc Open Heart 2023-01-01
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