Alexandre Gautier
A5041669754- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Atrial Fibrillation Management and Outcomes
- Long-Term Effects of COVID-19
- Cardiovascular Function and Risk Factors
- Regional Development and Policy
- Blood transfusion and management
- Sepsis Diagnosis and Treatment
- Erythropoietin and Anemia Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiovascular Conditions and Treatments
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Retirement, Disability, and Employment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Erythrocyte Function and Pathophysiology
- Island Studies and Pacific Affairs
- Migration, Aging, and Tourism Studies
- Aging, Elder Care, and Social Issues
Hôpital Bichat-Claude-Bernard
2019-2024
Assistance Publique – Hôpitaux de Paris
2020-2024
Institut Cardiovasculaire Paris Sud
2020-2024
Inserm
2018-2024
Université Paris Cité
2018-2024
Laboratoire de Recherche Vasculaire Translationnelle
2018-2024
Université Claude Bernard Lyon 1
2019-2023
Hôpital Privé Jacques Cartier
2021-2023
Délégation Paris 7
2020
Hôpital Européen Georges-Pompidou
2019
The optimal timing to perform percutaneous coronary interventions (PCI) in transcatheter aortic valve implantation (TAVI) patients remains unknown.
Inflammatory mediators, including blood cells and their products, contribute critically to atherogenesis, but the igniting triggers of inflammation remain elusive. Atherosclerosis develops at sites flow perturbation, where enhanced haemodynamic stress could initiate atherogenic inflammatory process due occurrence mechanic injury. We investigated role stress-induced breaches, allowing entry in arterial intima, triggering inflammation-driven atherogenesis.Human coronary samples isolated from...
The best management of stable coronary artery disease (CAD) in patients undergoing transcatheter aortic valve implantation (TAVI) is still unclear due to the marked inconsistency available evidence.The REVASC-TAVI registry (Management Myocardial Revascularization Patients Undergoing Transcatheter Aortic Valve Implantation With Coronary Artery Disease) collected data from 30 centers worldwide on TAVI who had significant, CAD at preprocedural work-up. For purposes this analysis, with either...
The optimal hemoglobin threshold to guide red blood cell (RBC) transfusion for patients with acute myocardial infarction (MI) and anemia is uncertain. To estimate the efficacy of 4 individual thresholds (<10 g/dL [<100 g/L], <9 [<90 <8 [<80 <7 [<70 g/L]) in MI anemia. Prespecified secondary analysis MINT (Myocardial Ischemia Transfusion) trial using target emulation methods. (ClinicalTrials.gov: NCT02981407). 144 clinical sites 6 countries. 3492 participants a level below 10 g/dL. Four...
Abstract Aims Although cardiac involvement has prognostic significance in coronavirus disease 2019 (COVID-19) and is associated with severe forms, few studies have explored the role of transthoracic echocardiography (TTE). We investigated link between TTE parameters prognosis COVID-19. Methods results Consecutive patients COVID-19 admitted to 24 French hospitals were retrospectively included. Comprehensive data, including clinical biological parameters, recorded at admission. Focused was...
Abstract Background and aims Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study to describe the incidence, predictors, impact cardiovascular (CV) outcomes of NOAF CCS patients. Methods from international (45 countries) CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF stable arterY disease) were used. Among 29 001 outpatients without previously reported AF at baseline, least one episode AF/flutter diagnosed...
Abstract Introduction Long drug‐eluting stents may limit the issue of overlapping multiple when treating long coronary lesions. Aim The aim study was to assess safety and efficacy 48 mm Xience Xpedition everolimus‐eluting stent (48mm‐EES) for treatment lesions, in an all‐comer population. Methods Patients receiving at least one 48mm‐EES were prospectively included from March 2014 December 2018. primary endpoint target lesion failure (TLF), defined as a composite cardiac death, vessel...
Abstract Background and Aims Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study aims to describe the incidence, predictors impact cardiovascular outcomes of NOAF CCS patients. Methods from international (45 countries) CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF stable arterY disease) were used. Among 29,001 outpatients without previously reported AF at baseline, least one episode AF/flutter diagnosed...
Although 18-45-year-old (y-o) patients represent a significant proportion of hospitalized for COVID-19, data concerning the young population remain scarce. The Critical COVID France (CCF) study was an observational including consecutive COVID-19 in 24 centers between 26 February and 20 April 2020. primary composite outcome included transfer to intensive care unit (ICU) or in-hospital death. Secondary outcomes were cardiovascular (CV) complications. Among 2868 patients, 321 (11.2%) 18-45-y-o...
Abstract Background: To compare the clinical outcomes between patients with and without diabetes admitted to hospital COVID-19. Methods: Retrospective multicentre cohort study from 24 academic tertiary medical centres in France including 2851 (675 diabetes) hospitalised for COVID-19 February 26 April 20, 2020. A propensity score matching method (1:1 patient characteristics, history, vital signs, laboratory results) was used (n=603 each group). The primary outcome admission intensive care...