- Disaster Response and Management
- Congenital Diaphragmatic Hernia Studies
- Blood transfusion and management
- Clinical Reasoning and Diagnostic Skills
- Erythropoietin and Anemia Treatment
- Venous Thromboembolism Diagnosis and Management
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- Cerebral Venous Sinus Thrombosis
- COVID-19 and healthcare impacts
- Hemoglobinopathies and Related Disorders
- Tracheal and airway disorders
- Intramuscular injections and effects
- Central Venous Catheters and Hemodialysis
- Palliative Care and End-of-Life Issues
- Frailty in Older Adults
- Family and Patient Care in Intensive Care Units
- Thyroid and Parathyroid Surgery
- Renal Transplantation Outcomes and Treatments
- Diabetes and associated disorders
- Medical Education and Admissions
- Healthcare professionals’ stress and burnout
- Blood donation and transfusion practices
- Heparin-Induced Thrombocytopenia and Thrombosis
- Clinical practice guidelines implementation
Queen's University
2021-2024
University of Minnesota
2023
St. Joseph’s Healthcare Hamilton
2015-2022
St John of God Hospital
2022
The University of Western Australia
2022
University of Lucerne
2022
McMaster University
2015-2022
St John of God Murdoch Hospital
2022
Hamilton Health Sciences
2021
The optimal hemoglobin threshold to guide red blood cell (RBC) transfusion for patients with acute myocardial infarction (MI) and anemia is uncertain. To estimate the efficacy of 4 individual thresholds (<10 g/dL [<100 g/L], <9 [<90 <8 [<80 <7 [<70 g/L]) in MI anemia. Prespecified secondary analysis MINT (Myocardial Ischemia Transfusion) trial using target emulation methods. (ClinicalTrials.gov: NCT02981407). 144 clinical sites 6 countries. 3492 participants a level below 10 g/dL. Four...
Background Patients diagnosed with pulmonary embolism (PE) are reported to experience symptoms of posttraumatic stress disorder (PTSD) and existential anxiety following their diagnosis. They may also negative changes in perspective hypervigilance PE symptoms. Objective The aim this study was document the mental emotional associated diagnosis through lens PTSD, better understand factors involved psychological distress receipt a Patients/Methods This mixed-methods two parts: (i) measurement...
The pandemic has upended much clinical care, irrevocably changing our health systems and thrusting emergency physicians into a time of great uncertainty change. This study is follow-up to survey that examined the early experience among Canadian aimed qualitatively describe experiences these during global pandemic. was conducted at when COVID-19 case numbers were low.The investigators engaged in an interview-based used interpretive description analytic technique, sensitised by principles...
Emergency department (ED) visits and readmissions after thoracic surgery are a major health care problem. We hypothesized that the addition of novel post-discharge mobile app specific to an existing home program would reduce ED compared alone.We conducted prospective cohort study patients undergoing lung resection for malignant disease between November 2016 May 2018. Patients received either alone (control group) or plus patient-input (intervention group). Primary outcomes were 30-day...
<p>Background The pandemic has upended much clinical care, irrevocably changing our health systems and thrusting emergency physicians into a time of great uncertainty change. This study is follow-up to survey that examined the early experience among Canadian aimed qualitatively describe experiences these during global pandemic. was conducted at when COVID-19 case numbers were low.</p> <p>Methods investigators engaged in an interview-based used interpretive description...
<p>Background The pandemic has upended much clinical care, irrevocably changing our health systems and thrusting emergency physicians into a time of great uncertainty change. This study is follow-up to survey that examined the early experience among Canadian aimed qualitatively describe experiences these during global pandemic. was conducted at when COVID-19 case numbers were low.</p> <p>Methods investigators engaged in an interview-based used interpretive description...
Background: For islet cell replacement strategies to be leveraged their full potential in diabetes care, rejection of transplanted human primary or stem cell-derived islets must prevented without maintenance immunosuppression. Two peritransplant infusions apoptotic donor leukocytes (ADLs) under induction immunosuppression (IIS) safely induced long-term tolerance via depletion alloreactive T cells and expansion several regulatory subsets. A deeper understanding the immune mechanisms...
Abstract Background Immunocompromised patients are inherently vulnerable to severe outcomes vaccine preventable infections compared the general population. This study aims investigate impact of immunosuppression on response ChAdOx1nCov-19 and BNT162b2 vaccines better inform vaccination efforts in this cohort. Methods A three-armed randomised controlled trial was performed. Patients with autoimmune disorders immunosuppressive therapies healthy controls were recruited from two sites....