- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Acute Ischemic Stroke Management
- Coronary Artery Anomalies
- Hemodynamic Monitoring and Therapy
- Peripheral Artery Disease Management
- Mechanical Circulatory Support Devices
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Social Media in Health Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Advanced MRI Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
Assistance Publique – Hôpitaux de Paris
2014-2025
Université Paris Cité
2014-2025
Hôpital Cochin
1996-2025
Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale
2018-2025
Paris Cardiovascular Research Center
2019-2025
Inserm
1996-2025
Hôpital Européen Georges-Pompidou
2019-2025
Centre Hospitalier Intercommunal André Grégoire Montreuil
2024
Centre Hospitalier Universitaire de Lille
2024
Université de Limoges
2024
The Nexfin device estimates arterial pressure by the volume clamp method through a finger pneumatic cuff. It also allows to estimate cardiac index (CInoninv) pulse contour analysis of non-invasive curve. We evaluated ability track changes in induced fluid challenge.We included 45 patients for whom expansion (500 mL saline infused over 30 min) was planned. expansion-induced measured transpulmonary thermodilution (CIinv, PiCCO device) and CInoninv were recorded.In seven patients, could not...
Background: Patients with rheumatoid arthritis (RA) and other chronic inflammatory rheumatic disorders have increased risk of cardiovascular disease (CVD) venous thromboembolism (VTE) compared the general population. Moreover, recent data raised concerns around a possible major CV events (MACE) VTE in patients treated JAK inhibitors (JAKi). In October 2022, PRAC has recommended measures to minimize serious side effects, including conditions VTE, associated all approved diseases. Objective:...
Objective Epicardial adipose tissue (EAT) is suggested to correlate with metabolic risk factors and promote plaque development in the coronary arteries. We sought determine whether EAT thickness was associated or not presence extent of angiographic artery disease (CAD). Methods measured epicardial fat by computed tomography assessed CAD angiography participants from prospective EVASCAN study. The association cardiovascular factors, calcification scoring using multivariate regression...
Inhibition of adenosine A2A receptor (A2AR) is a promising approach for cancer immunotherapy currently evaluated in several clinical trials. We here report that anti-obesogenic and anti-inflammatory functions A2AR, however, significantly restrain hepatocellular carcinoma (HCC) development. Adora2a deletion mice triggers obesity, non-alcoholic steatohepatitis (NASH), systemic inflammation, leading to spontaneous HCC promoting dimethylbenzyl-anthracene (DMBA)- or diethylnitrosamine...
Pham, Vincent; Picard, Fabien; Monnot, Sebastien; Garrigoux, Pierre; Jegou, Arnaud; Dambrin, Grégoire; Paul, Jean-François Author Information
Abstract Background and aims Data on new-onset atrial fibrillation (NOAF) in patients with chronic coronary syndromes (CCS) are scarce. This study to describe the incidence, predictors, impact cardiovascular (CV) outcomes of NOAF CCS patients. Methods from international (45 countries) CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF stable arterY disease) were used. Among 29 001 outpatients without previously reported AF at baseline, least one episode AF/flutter diagnosed...
Background: Simulator-based teaching for coronary angiography (CA) is an attractive educational tool medical students to improve their knowledge and skills. Its pedagogical impact has not been fully evaluated yet.
Background— There is little evidence regarding the efficacy and safety of bioresorbable scaffolds (BRS) for percutaneous treatment chronic total occlusions. Methods Results— We performed a multicenter registry consecutive occlusion patients treated with BRS (Absorb; Abbott Vascular) second-generation drug-eluting stents (DES) at 5 institutions. Long-term target-vessel failure (a composite cardiac death, myocardial infarction, ischemia-driven target-lesion revascularization) was primary end...
Abstract Aims Although recreational drug use may induce ST-elevated myocardial infarction (STEMI), its prevalence in patients hospitalized intensive cardiac care units (ICCUs), as well short-term cardiovascular consequences, remains unknown. We aimed to assess the in-hospital prognosis of STEMI with from ADDICT-ICCU study. Methods and results From 7–22 April 2021, was detected prospectively by a systematic urine multidrug test all consecutive admitted for 39 ICCUs across France. The primary...
Background Absolute hyperemic coronary blood flow and microvascular resistances can be measured by continuous thermodilution with a dedicated infusion catheter. We aimed to determine the mechanisms of this response in animal. Methods Results Twenty open chest pigs were instrumented probes on arteries. The following possible saline‐induced hyperemia explored compared maximal achieve adenosine testing: (1) various rates; (2) content temperature; (3) NO production inhibition L‐arginine methyl...
Edge to edge transcatheter mitral valve repair with MitraClip (Abbott Vascular, Menlo Park, CA) is increasing for high‐risk surgical patients significant regurgitation. Patients congenitally corrected transposition of the great arteries (CCTGA) presenting tricuspid regurgitation a systemic right ventricle may represent particularly challenging candidates given their anatomy. We report case 67‐year‐old gentleman CCTGA and severe who was referred implantation after heart team consensus....