Drew Stark

ORCID: 0009-0006-3394-160X
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About
Contact & Profiles
Research Areas
  • Viral Infectious Diseases and Gene Expression in Insects
  • Protein Degradation and Inhibitors
  • Cellular transport and secretion
  • Retinal Development and Disorders
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Genetics and Neurodevelopmental Disorders

University of Michigan
2022

Inter-organellar communication is critical for cellular metabolic homeostasis. One of the most abundant inter-organellar interactions are those at endoplasmic reticulum and mitochondria contact sites (ERMCS). However, a detailed understanding mechanisms governing ERMCS regulation their roles in metabolism limited by lack tools that permit temporal induction reversal. Through unbiased screening approaches, we identified fedratinib, an FDA-approved drug, dramatically increases abundance...

10.1101/2024.02.02.578646 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-04
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