A5102793290- vaccines and immunoinformatics approaches
- Mosquito-borne diseases and control
- Thyroid Disorders and Treatments
- Virology and Viral Diseases
- Education and Critical Thinking Development
- Respiratory viral infections research
- Innovations in Medical Education
- Problem and Project Based Learning
- Bacteriophages and microbial interactions
- Pneumonia and Respiratory Infections
- MicroRNA in disease regulation
- Immune Cell Function and Interaction
- Actinomycetales infections and treatment
- Cancer-related molecular mechanisms research
- Antimicrobial Peptides and Activities
- Wound Healing and Treatments
- RNA and protein synthesis mechanisms
- Peptidase Inhibition and Analysis
- Thyroid Cancer Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- RNA modifications and cancer
- Viral gastroenteritis research and epidemiology
- Immunotherapy and Immune Responses
- Veterinary medicine and infectious diseases
- Renal function and acid-base balance
Xiangya Hospital Central South University
2022-2024
Central South University
2022-2024
Hunan Provincial Center for Disease Control and Prevention
2022-2024
Guizhou Provincial People's Hospital
2023-2024
Novem (Netherlands)
2023
Shandong First Medical University
2023
Creative Commons
2023
Alveolar epithelial cell damage is an important determinant of the severity acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, molecular mechanisms alveolar death during development ALI/ARDS remain unclear. In this study, we explore role miR-29a-3p in and its mechanism. Plasma samples were collected from healthy controls ARDS patients. Mice intratracheally instilled with lipopolysaccharide (LPS) to establish injury. N6-adenosine (m6A) quantification, RNA-binding...
Background Nocardia genus, a complex group of species classified to be aerobic actinomycete, can lead severe concurrent infection as well disseminated infection, typically in immunocompromised patients. With the expansion susceptible population, incidence has been gradually growing, accompanied by increased resistance pathogen existing therapeutics. However, there is no effective vaccine against this yet. In study, multi-epitope was designed using reverse vaccinology combined with...
Human metapneumovirus (HMPV) is one of the main pathogens causing severe respiratory infections in children, as a common cause immunodeficiency-related deaths children and elderly individuals, prevalence HMPV has been showing an increasing trend during last years. However, no vaccines or effective treatment plans are available currently. In this present, based on candidate proteins highly associated with viral virulence promising protective potential, we screened for immunodominant cytotoxic...
Background: The integration of Large Language Models (LLMs) into nursing education presents a novel approach to enhancing critical thinking skills. This study evaluated the effectiveness LLM-assisted Problem-Based Learning (PBL) compared traditional PBL in improving skills among students. Methods: Participants were randomly assigned either group (50 students) or an LLM-integrated students). California Critical Skills test was used assess Results: showed more pronounced increase (0.60 points)...
Chikungunya virus (CHIKV), a type A borne by mosquitoes that can cause major clinical manifestations including rash, fever and debilitating arthritis, grown into reemerging serious public health issue. Currently, there is no licensed therapy or vaccine available for CHIKV, although the most promising form of treatment appears to be immunotherapy. Neutralizing antibodies CHIKV provide high protection all strains, as well other alphaviruses. Development protective may an effective strategy...
Staphylococcus aureus is an extraordinarily versatile pathogen, which currently the most common cause of nosocomial and community infections. Considering that increased antibiotic resistance may hasten spread S. aureus, developing effective vaccine can possibly aid in its control. The RNA coding immunodominance epitopes from bacteria provide a potential method to induce T B cell immune responses by translating them into cells. Furthermore, using bioinformatics create circular vaccines ensure...
To investigate effectiveness of a novel suture method-stepwise progressive ultra-tension-reducing method in closing high-tension wounds on the chest, back, and limbs.
Abstract Acinetobacter baumannii , a Gram-negative opportunistic pathogen that widely exists in the environment, causes numerous nosocomial infection cases ICU. As agent of pneumonia, septicemia, and meningitis, A. is usually multidrug-resistant has high mortality rate. In this study, we aimed to develop vaccine for through silico prediction. With help immunoinformatic methods, which have proven be effective convenient, our team managed multiepitope subunit vaccines . Three proteins closely...