- COVID-19 Clinical Research Studies
- Drug-Induced Ocular Toxicity
- Vitamin C and Antioxidants Research
- Cannabis and Cannabinoid Research
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Veterinary medicine and infectious diseases
- Coccidia and coccidiosis research
- Extracellular vesicles in disease
- Cellular transport and secretion
- Alcohol Consumption and Health Effects
- Autophagy in Disease and Therapy
- Animal Nutrition and Physiology
Nanjing Agricultural University
2022-2023
Henan University of Traditional Chinese Medicine
2023
Coccidiosis is a worldwide epidemic intestinal disease with high incidence, which causes huge economic losses. Halofuginone hydrobromide (HF) widely applied as an effective anticoccidial drug in the poultry industry. However, its therapeutic efficacy severely restrained due to toxic effects, poor aqueous solubility and low permeability. Nanotechnology can improve biological effect of drugs, thus, reduce administered doses effects. The objective this study was investigate preventive potential...
Chloroquine was once thought to be a promising treatment for COVID-19 but it quickly failed due its inefficiency and association with increased mortality. Further, comorbidities such as hypertension may have contributed this failure. The safety toxicity of chloroquine at doses required treating SARS-CoV-2 infection in hypertensive patients remain unknown. Herein, investigate these effects, we performed evaluation the approved dose (63 mg/kg) high (126 rats. We found that mortality rats 18.2%...