Zhaochen Wu

ORCID: 0009-0006-6869-6712
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Research Areas
  • Fungal Plant Pathogen Control
  • Plant-Microbe Interactions and Immunity
  • Plant Disease Resistance and Genetics
  • Plant Disease Management Techniques
  • Plant chemical constituents analysis
  • Plant Gene Expression Analysis
  • Plant Pathogens and Fungal Diseases
  • Lipid metabolism and biosynthesis
  • Genomics, phytochemicals, and oxidative stress
  • Nitrogen and Sulfur Effects on Brassica
  • Microbial Natural Products and Biosynthesis
  • Layered Double Hydroxides Synthesis and Applications
  • Mechanical Circulatory Support Devices
  • Pulmonary Hypertension Research and Treatments
  • Insect-Plant Interactions and Control
  • Geophysics and Sensor Technology
  • Chromatography in Natural Products
  • Plant Stress Responses and Tolerance
  • Agricultural safety and regulations
  • Ginseng Biological Effects and Applications
  • Congenital Heart Disease Studies
  • Topological Materials and Phenomena
  • Mesoporous Materials and Catalysis
  • Polymer-Based Agricultural Enhancements
  • Insect and Pesticide Research

China Agricultural University
2021-2025

Fudan University
2025

Northwest A&F University
2018-2022

The emergence of MDR in plant pathogens is a threat to disease management and leads the use excessive fungicides. Botrytis cinerea particular concern because its has widely emerged field. Understanding genesis first step for controlling MDR. In this study, contribution PSMs been examined. Effective pathogen agroecosystems relies on better understanding how it copes with phytochemicals or

10.1128/mbio.02237-23 article EN cc-by mBio 2024-01-23

Zanthoxylum bungeanum (Rutaceae), a popular food flavoring and traditional Chinese medicine ingredient, is an important cash crop. Its leaves are rich in flavonoids with multiple bioactivities. However, the transcriptional sequencing has not been investigated, molecular basis for flavonoid biosynthesis remains unclear this plant. This paper, key (epicatechin, rutin, hyperoside, trifolin, quercitrin, afzelin) contents were determined of 10 Z. varieties from common garden. Results show mainly...

10.1021/acs.jafc.9b05732 article EN Journal of Agricultural and Food Chemistry 2019-11-12

Plant pathogens have frequently shown multidrug resistance (MDR) in the field, often linked to efflux and sometimes metabolism of fungicides. To investigate potential role metabolic B. cinerea strains showing MDR, azoxystrobin-sensitive strain B05.10 -resistant Bc242 were treated with azoxystrobin. The degradation half-life azoxystrobin (9.63 days) was shorter than that (28.88 days). Azoxystrobin acid, identified as a metabolite, exhibited significantly lower inhibition rates on colony...

10.1021/acs.jafc.4c02409 article EN Journal of Agricultural and Food Chemistry 2024-04-18

Fungicides are an indispensable tool in plant disease control. Various modes of action (MOAs) have been identified different fungicides to suppress pathogens. The combined use with distinct MOAs has recommended prevent the development pathogen resistance. In studying MOAs, metabolomics proven be a robust and high-throughput method. Because metabolites unique depending on biological activities organism, can classified by establishing metabolic fingerprinting profiles. Similarly, if fungicide...

10.1016/j.aac.2024.05.001 article EN cc-by-nc-nd Advanced Agrochem 2024-05-31

Colletotrichum gloeosporioides is a major pathogen causing anthracnose of pepper (Capsicum annuum). In agricultural production, it typically managed using fungicides like fluazinam. However, the frequent use raises concerns about potential development fungicide resistance. This issue has not been extensively documented. To address this, 102 isolates C. were collected from in fields. The EC50 values these to fluazinam exhibited unimodal distribution with mean value 0.18 ± 0.14 μg/mL,...

10.1021/acs.jafc.4c11478 article EN Journal of Agricultural and Food Chemistry 2025-03-18

In response to pathogen infection, some plants increase production of secondary metabolites, which not only enhance plant defense but also induce fungicide resistance, especially multidrug resistance (MDR) in the through preadaptation. To investigate cause MDR Botrytis cinerea, grapes 'Victoria' (susceptible B. cinerea) and 'Shine Muscat' (resistant were inoculated into seedling leaves with followed by extraction metabolites from on days 3, 6, 9 after inoculation. The extract was analyzed...

10.3390/metabo13050654 article EN cc-by Metabolites 2023-05-13

Abstract Quercitrin, hyperoside, rutin, and afzelin are the dominant flavonoids compounds from Zanthoxylum bungeanum leaves, they play major roles in antioxidant activity. Macroporous adsorption resin (MAR) treatment, a simple, low‐cost efficient method, was combined with ultrasound‐assisted extraction (UAE) to enrich purify these four Z. leaves efficiently. The optimal conditions for UAE based on Response Surface Methodology (RSM) were determined be an ethanol concentration of 60%, size 40...

10.1111/1750-3841.14282 article EN Journal of Food Science 2018-08-01

The necrotrophic pathogen Botrytis cinerea infects a broad range of plant hosts and causes substantial economic losses to many crops. Although resistance procymidone has been observed in the field, it remains uncertain why is usually involved multidrug (MDR) together with other fungicides. Nine mutants derived from B. strain B05.10 through domestication exhibited high factors (RFs) against both fludioxonil. However, fitness was reduced compared their parental strain, showing non-sporulation...

10.3390/jof10040261 article EN cc-by Journal of Fungi 2024-03-29

Abstract BACKGROUND Coating seed with pesticides is an effective way to control plant pests, however, factory‐based coating processes may carry a potential risk operational workers of chemical exposure. To study the risk, carbofuran and tebuconazole were used coat corn their subsequent distribution on bodies was measured at manufacturers XFS LS (Shanxi, China). Clothing collected from during operations analyzed using high‐performance liquid chromatography. RESULTS At XFS, dermal exposure...

10.1002/ps.6315 article EN Pest Management Science 2021-02-03

The probenazole fungicide is used for controlling rice blast (Magnaporthe grisea) primarily by inducing disease resistance of the plant. To investigate mechanism induced plant defense, seedlings were treated with at 15 days post emergence, and non-treated plants control. infected M. grisea 5 after chemical treatment incubated in a greenhouse. After 7 days, sampled. metabolome was chemically extracted analyzed using gas chromatography mass spectrum (GC-MS). GC-MS data processed analysis...

10.3390/metabo11040246 article EN cc-by Metabolites 2021-04-16

Bound states in the continuum (BICs) are exotic optical topological singularities that defy typical radiation within of radiative modes and carry polarization vortices momentum space. Enabling ultrahigh quality factors, BICs have been applied realizing lasing Bose-Einstein condensation via micro-/nano- photonic structures, their momentum-space vortex topologies exploited passive systems, revealing novel spin-orbit effects. However, as representative properties, spin-orbit-related phenemona...

10.48550/arxiv.2407.20093 preprint EN arXiv (Cornell University) 2024-07-29

The spicy taste and medicinal properties of Zanthoxylum bungeanum are imparted by several alkylamides. Although most studies have focused on their isolation identification, few reported biosynthesis pathways. Among the differentially expressed genes (DEGs) in numerous varieties Z. bungeanum, some might contribute to alkylamide biosynthesis. However, they not yet functionally validated. present study explored function two genes, ZbFAD2 ZbFAD3, pathway, stable transient expression Arabidopsis...

10.3389/fpls.2022.991882 article EN cc-by Frontiers in Plant Science 2022-09-23
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