- Genomics and Phylogenetic Studies
- Fuzzy Systems and Optimization
- Fuzzy Logic and Control Systems
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Diagnosis and treatment of tuberculosis
- Hepatitis Viruses Studies and Epidemiology
- Tuberculosis Research and Epidemiology
- Microbial Metabolic Engineering and Bioproduction
- Viral Infections and Immunology Research
- Microbial infections and disease research
- Rabies epidemiology and control
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
- Multi-Criteria Decision Making
- Neural Networks and Applications
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
San Diego State University
2023
Animal and Plant Health Agency
2014-2022
Veterinary Medicines Directorate
2009
University of Manchester
2002
SUMMARY The prevalence of anti-HEV isotype-specific antibodies and viraemia were investigated in serum samples collected from slaughter-age pigs (aged 22–24 weeks) 23 farms Scotland. Of 176 tested, 29·0% ( n = 51) IgG positive, 36·9% 65) IgA positive IgM positive. Overall seroprevalence (anti-HEV IgG+ and/or IgA+ IgM+) was 61·4% 108). HEV RNA detected 72/162 (44·4%). Partial sequence ORF2 (98 nt) obtained eight RNA-positive phylogenetic analysis confirmed that they all genotype 3. This is...
BOVINE tuberculosis (TB) caused by Mycobacterium bovis is a major problem in British cattle. Furthermore, M infection has been documented many other mammals, with badgers acting as an important reservoir and vector of for cattle the west England parts Wales. However, few exceptions, bovine TB epidemic not significantly affected companion animal populations, which are considered 'spillover' hosts (Shrikrishna others 2009, Broughan 2013, Gunn-Moore 2013). In seven years (2006/12) since pet...
Abstract Improvements in cost and speed of next generation sequencing (NGS) have provided a new pathway for delivering disease diagnosis, molecular typing, detection antimicrobial resistance (AMR). Numerous published methods protocols exist, but lack harmonisation has hampered meaningful comparisons between results produced by different methods/protocols vital global genomic diagnostics surveillance. As an exemplar, this study evaluated the sensitivity specificity five well-established...
The paper gives a brief review of the basic mathematical aspects random set theory. Concepts such as mapping and its coverage function are introduced in comprehensive way, avoiding too much detail. We adapt this theory to system identification forecasting time series. This is achieved by using one-point possibility measure process which generates defines fuzzy set, we thereby establish relationship between statistical objects systems. obtained way can be used for either prediction or...
Constraint-based metabolic modeling approaches have enhanced our knowledge and understanding of the metabolism prokaryotes eukaryotes. This approach highly depends on reconstruction process genome-scale models (Mmodels). M-models can guide effective experimental design yield new insights into function control biological systems. Despite recent advances in automated generation draft network reconstructions, manual curation these networks remains a labor-intensive challenging task. Thus, ten...
One of the main reasons why histograms are most used density estimators is that they easier to implement and interpret than other estimators. Some people have already exploited connection between probability theory possibility or fuzzy sets set up membership functions create models. Two different ways been used: 1) transform function a random variable into measure, which an almost automatic operation; 2) calculate coverage set, measure. In this paper, we show histogram determined set. This...
Abstract Improvements in cost and speed of next generation sequencing (NGS) have provided a new pathway for delivering disease diagnosis, molecular typing, detection antimicrobial resistance (AMR). Numerous published methods protocols exist, but lack harmonisation has hampered meaningful comparisons between results produced by different methods/protocols vital global genomic diagnostics surveillance. As an exemplar, this study evaluated the sensitivity specificity five well-established...