A5100640602- Pneumonia and Respiratory Infections
- Diabetes Treatment and Management
- Transplantation: Methods and Outcomes
- Traditional Chinese Medicine Studies
- Heart Failure Treatment and Management
- Healthcare and Venom Research
- Dialysis and Renal Disease Management
- Human Health and Disease
- Liver Disease Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Tendon Structure and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Analytical Chemistry and Chromatography
- Cancer Risks and Factors
- Climate Change and Health Impacts
- Global Cancer Incidence and Screening
- Ferroptosis and cancer prognosis
- Bee Products Chemical Analysis
- Drug Transport and Resistance Mechanisms
- Alcohol Consumption and Health Effects
- Hearing, Cochlea, Tinnitus, Genetics
- Neurological and metabolic disorders
- Obstructive Sleep Apnea Research
- Hearing Loss and Rehabilitation
- Cancer, Lipids, and Metabolism
Yale New Haven Hospital
2024
Harvard University
2021-2024
Mount Auburn Hospital
2021-2024
First People's Hospital of Foshan
2024
National Center for Chronic and Noncommunicable Disease Control and Prevention
2021-2022
Southern Medical University
2021
Nanfang Hospital
2021
Liaocheng People's Hospital
2012-2018
State Key Laboratory of Reproductive Medicine
2017
Nanjing Medical University
2017
PURPOSE AML accounts for 80% of acute leukemia in adults. While progress has been made treating younger patients the past 2 decades, there limited improvement older until recently. This study examines global and European Union (EU) 15+ trends between 1990 2019. METHODS We extracted age-standardized incidence rates (ASIRs), death (ASMRs), disability-adjusted life years, stratified by sex from Global Burden Disease Study database, mortality-to-incidence ratio (MIR) were computed. Trends...
The global incidence of gout has increased rapidly, likely secondary to the increase in prevalence conditions that predispose gout, such as obesity. Depending on population studied, ranges from less than 1 6.8%. Thus, can be a significant burden healthcare systems. objective this study is observe trends incidence, prevalence, and disability-adjusted life years (DALYs) between 1990 2019 globally European Union (EU) 15+ nations. We extracted data Global Burden Disease Study database based...
Elevated levels of insulin-like growth factor-I (IGF-I) are associated with carcinogenesis and cancer progression. However, the molecular mechanisms by which IGF-I promotes prostate development remain to be elucidated. Docetaxel chemotherapy is an important therapeutic strategy in many types human cancers including cancer. In this study, we showed that rendered PC-3 DU145 cells more resistant docetaxel treatment. treatment decreased miR-143 expression, but increased expression receptor...
The incidence of colorectal cancer (CRC) in the U.S. is declining adults 50 years and older; however, recent studies suggest an increasing disease burden among under age 50. This study aims to compare incidence, mortality, mortality-to-incidence ratios (MIRs) CRC EU15+ countries determine if similar age-stratified occurrences are observed across these with “Western lifestyle”-related risk factors. Incidence mortality rates for between 1990 2019 were extracted using Global Burden Disease...
Objective: To analyze mortality and its trend of chronic respiratory diseases (CRD) in China from 1990 to 2019. Methods: Based on the provincial results 2019 Global Burden Disease (GBD) study, average annual percent change (AAPC) standardized rates different CRDs were analyzed by using Joinpoint 4.8.0.1, age-standardized rate CRD was calculated GBD world standard population. comparative risk assessment theory GBD, attributable deaths due 12 factors estimated, including smoking, indoor air...
Objective: To analyze the trend of incidence, mortality and disease burden breast cancer in women China during 1990-2017. Methods: Based on estimation data from Global Burden Disease 2017 (GBD2017), incidence,mortality, disability- adjusted life years (DALY), lost (YLL), lived with disability (YLD) for 1990-2017 were standardized by world standard population used GBD2017. The GBD study applied attributable formula to estimate deaths five risk factors cancer, including alcohol use, high body...
Prostate cancer (PRAD) is one of the common malignant tumors urinary system. In order to predict treatment results for PRAD patients, this study proposes develop a risk profile based on endoplasmic reticulum stress (ERS). Based Memorial Sloan-Kettering Cancer Center (MSKCC) cohort and Gene Expression Omnibus database (GSE70769), we verified predictive signature. Using random survival forest analysis, prognostically significant ERS-related genes were found. An score (ERscore) was created...
Objective To observe the incidence and clinical characteristics of chronic Keshan disease in recent years, to provide evidence for diagnosis disease. Methods From March August 2009, 163 patients with were chosen from Shandong, Sichuan, Inner Mongolia Cansu. Of these patients, 62 cases 34 37 Mongolia, 30 Gansu. All subjects underwent detailed natural history disease, careful physical examination electrocardiogram (ECG), X-ray chest radiography cardiac ultrasound examination. The features...
The novel coronavirus, or COVID-19, emerged from Wuhan, Hubei Province, China, and has recently spread all over the world. During COVID-19 pandemic, healthcare workers struggle against this microscopic enemy due to their job responsibilities, thus leading be infected in some of them, even them are died line duty. As 2 February 2021, 37 million cases among health 183 countries regions were reported World Health Organization (WHO), a figure that represents 36% total globally. median age these...
Objective To explore potential influence factors on the dimensions of upper airway in children. Methods 50 children aged from 7 to 13 years old (20 males, 30 females) were selected. Their maxillary development between normal deficienct (SNA 79.85±3.49°), while mandible ranged overdue (SNB 81.55±3.71°). All underwent CBCT scan and their 41 dental, occlusal, jaw facial cephalometric variables measured with Dolphin Software evaluate height, sectional area corresponding volume 3 parts...
3583 Background: The mortality of colorectal cancer remains high despite the development novel anti-neoplastic agents. Preclinical studies have shown that upregulates expression sodium-glucose cotransporter 2 (SGLT2) channels and inhibition these by SGLT2 inhibitors (SGLT2i) reduces tumor proliferation. We aimed to investigate impact SGLT2i on outcome patients with cancer. Methods: conducted a retrospective cohort study including all adult adenocarcinoma type diabetes mellitus in two...
Cardiac allograft vasculopathy is the leading cause of death after first year heart transplantation. The optimal treatment for unprotected left main coronary artery disease in orthotopic transplantation (OHT) patients unknown. Two OHT with following underwent percutaneous intervention (PCI). Technical success was achieved drug-eluting stents inserted to cover lesions artery. After 16 months follow-up, one patient died multiorgan failure, other alive and free from myocardial infarction or...
Fas knockout (Fas−/-) mice are a model for systemic lupus erythematosus (SLE) -like autoimmune syndromes. We aimed to induce atherosclerosis (AS) in Fas−/- mice. Sixteen male were included the study, sex-matched C57B6/L (B6) and apolipoprotein E-knockout (ApoE−/-) negative positive AS controls, respectively. A silica collar was placed around right carotid artery of each mouse development. All fed 24-week high-fat diet, investigated lesions. also compared levels blood lipid glucose, serum...