A5044673820- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Bioactive Compounds and Antitumor Agents
- MicroRNA in disease regulation
- Cancer Cells and Metastasis
- PI3K/AKT/mTOR signaling in cancer
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
- Cancer Mechanisms and Therapy
- Ubiquitin and proteasome pathways
- Extracellular vesicles in disease
- Autophagy in Disease and Therapy
- Atherosclerosis and Cardiovascular Diseases
- Garlic and Onion Studies
- Antioxidant Activity and Oxidative Stress
University of South China
2023-2024
Second Affiliated Hospital of Jilin University
2021
Jilin Province Science and Technology Department
2019
Yanbian University
2019
Guangdong Provincial People's Hospital
2015
Southern Medical University
2015
Abstract Ferroptosis, a therapeutic strategy for tumours, is regulated cell death characterised by the increased accumulation of iron-dependent lipid peroxides (LPO). Tumour-associated long non-coding RNAs (lncRNAs), when combined with traditional anti-cancer medicines or radiotherapy, can improve efficacy and decrease mortality in cancer. Investigating role ferroptosis-related lncRNAs may help strategise new options breast cancer (BC). Herein, we briefly discuss genes pathways ferroptosis...
The present study aimed to explore the effects of shikonin (SKN) on damage human venous endothelial cells (HUVECs) induced by ox-LDL and underlying molecular mechanism. HUVECs were randomly divided into six groups: control, ox-LDL, SKN + compound C, si-Nrf2, si-HO-1. MTT method was used detect cell viability, flow cytometry apoptosis reactive oxygen species (ROS) levels, Western blot protein levels. Compared control group, viability group decreased, rate increased, level cleaved caspase-3...