A5108586516- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Single-cell and spatial transcriptomics
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Obesity, Physical Activity, Diet
- Global Cancer Incidence and Screening
- Health disparities and outcomes
- Memory and Neural Mechanisms
- Colorectal Cancer Screening and Detection
- Food Security and Health in Diverse Populations
- Hydrogels: synthesis, properties, applications
- Neuroendocrine regulation and behavior
- Psychological Well-being and Life Satisfaction
- Public Health Policies and Education
- biodegradable polymer synthesis and properties
- Nutrition, Health and Food Behavior
- Eating Disorders and Behaviors
- Neuropeptides and Animal Physiology
- Connective tissue disorders research
- Pericarditis and Cardiac Tamponade
- Receptor Mechanisms and Signaling
- Protein Structure and Dynamics
- Veterinary Pharmacology and Anesthesia
- Gastric Cancer Management and Outcomes
Florida Agricultural and Mechanical University
2011-2024
Parahyangan Catholic University
2023
Massachusetts General Hospital
2021-2022
University of Washington
1974-2022
University of Vermont
2022
Moffitt Cancer Center
2018
Meharry Medical College
2017
Florida State University
2012
University of Kentucky
2003
Queen's University Belfast
1997
Abstract In general, proteins fold with hydrophobia residues buried, away from water. Reversible protein folding due to interactions results inverse temperature transitions where occurs on raising the temperature. Because homoiothermic animals constitute an infinite heat reservoir, it is transition temperature, T t , not endothermic of transition, that determines hydrophobically folded state polypeptides at body Reported here a new hydrophobicity scale based values for each amino acid...
Rats were trained with food reinforcement to discriminate the anxiogenic drug pentylenetetrazol (PTZ, 20 mg/kg) from saline in a two-lever-choice task. In Experiment 1, ethanol, 8.25% w/v was given by gavage (7/day) for 4 days, doses titrated maintain moderate intoxication. After termination of rats exhibited mild overt signs withdrawal and, discrimination tests as test substance, they selected PTZ lever, an effect reversed 2 g/kg, and diazepam, 5 mg/kg. 2, drank nutritionally complete...
C. M. Harris, S. E. Livingstone and I. H. Reece, J. Chem. Soc., 1959, 1505 DOI: 10.1039/JR9590001505
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Abstract Ligands for benzodiazepine receptors produce one of three types effects: (1) diazepamlike; (2) opposite to diazepam; or (3) no direct effects, but blockade the effects other ligands. Data refiewed in this paper demonstrate that imidazodiazepine Ro 15‐4513 produces neuronal and behavioral type those diazepam. These include electrophysiological behavioural seizures, anxiety‐like behaviors, inhibition aggression, facilitation learning memory. In addition its also blocks...
Purpose:The study applies the theory of planned behavior to explain fruit and vegetable eating behaviors, a broad construct consisting preparing, self-monitoring, consuming fruits vegetables, older African Americans.Design Methods: Structural equation modeling was used examine applicability with data from 211 American women men (73% women, 26% men; median age range 57-63 years) participating in larger intervention study.Results: Attitudes about subjective social norms, perceived behavioral...
Human papillomavirus (HPV) infection has been causally linked to six cancers, and many disproportionately affect minorties. This study reports on the development effectiveness of an intervention aimed at increasing HPV vaccine uptake among African American Hispanic pediatric patients in safety-net clinics. Formative research, community engagement, theory guided intervention. A clustered, non-randomized controlled pragmatic trial was conducted four clinics providing healthcare for underserved...
Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon, is major environmental pollutant. In this study, the effects of carcinogen/mutagen and one its metabolites, benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE), on human prostate carcinoma cell line DU145, were examined. Cell viability, DNA damage, cycle progression evaluated as toxic end-points. We have shown that B[a]P BPDE inhibited viability following 48 hr exposure. Furthermore, comet assay analyses revealed both induced strand breaks...
To examine (a) the influences of life dissatisfaction and dietary social support on eating behaviors (a high-fat diet fruit/vegetable consumption) older African Americans (b) moderating role perceived association between their unhealthy behaviors. Baseline data from a larger intervention study mid-life Americans. The incorporated quasi-experimental design with random selection participants, stratifying for age gender. Six churches in North Florida. One hundred seventy-eight (132 females 46...
Rats were trained to discriminate pentylenetetrazol (PTZ, an anxiogenic drug), 20.0 mg/kg, from saline using a food-maintained two-lever-choice task. When treated chronically with diazepam (DZP) and tested the benzodiazepine-receptor antagonist Ro 15-1788, withdrawal DZP produced PTZ-like stimulus in these subjects that was related directly dose of given every 8 hr for 6 days. In contrast, only highest (80 mg/kg/8 hr) even minimal physical signs precipitated abstinence after 15-1788....