A5022214864- Immunotherapy and Immune Responses
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mycorrhizal Fungi and Plant Interactions
- Fungal Biology and Applications
- Cardiovascular Function and Risk Factors
- Mitochondrial Function and Pathology
- Medical Imaging and Pathology Studies
- Cancer Cells and Metastasis
- Plant Parasitism and Resistance
- RNA Research and Splicing
- Hepatitis B Virus Studies
- Advanced Biosensing Techniques and Applications
- Cancer-related molecular mechanisms research
- ATP Synthase and ATPases Research
- Myasthenia Gravis and Thymoma
- Coal Properties and Utilization
- Hydrocarbon exploration and reservoir analysis
- Photosynthetic Processes and Mechanisms
- NMR spectroscopy and applications
- vaccines and immunoinformatics approaches
- Cardiac Imaging and Diagnostics
- Cardiac Fibrosis and Remodeling
- Cancer Research and Treatments
- RNA modifications and cancer
- Occupational and environmental lung diseases
Hebei University
2010-2024
Chongqing University
2019
Accurate identification of linear B-cell epitopes plays an important role in peptide vaccine designs, immunodiagnosis, and antibody productions. Although several prediction methods have been reported, unsatisfied accuracy has limited the broad usages epitope prediction. Therefore, developing a reliable model with significant improvement on is highly desirable.In this study, we developed novel for epitopes, APCpred, which was derived from combination amino acid anchoring pair composition...
Abstract The localization of translation can direct the polypeptide product to proper intracellular compartment. Our results reveal by cytosolic ribosomes on a domain chloroplast envelope in unicellular green alga Chlamydomonas (Chlamydomonas reinhardtii). We show that this isolated chloroplasts retains translationally active and mRNAs encoding proteins. This is aligned with localized zone, compartment where photosystem subunits encoded plastid genome are synthesized assembled. Roles...
Background The malignant mesothelioma (MM) survival rate has been hampered by the lack of efficient and accurate early detection methods. immune system may detect changes tumor progression responding with tumor-associated autoantibody production. Hence, in this study, we translated humoral response to cancer proteins into a potential blood test for MM. Methodology/Principal Findings A T7 phage MM cDNA library was constructed using tissues biopanned antigens (TAAs) pooled patient normal serum...
Atypical adenomatous hyperplasia (AAH) and squamous cell dysplasia (SCD) are associated with the development of malignant lesions in lung. Accurate diagnosis AAH SCD could facilitate earlier clinical intervention provide useful information for assessing lung cancer risk human populations. Detection has been achieved by imaging bronchoscopy clinically, but sensitivity specificity remain less than satisfactory. We utilized ability immune system to identify lesion specific proteins detection...
Diabetic cardiomyopathy (DCM) is a primary cause of death in diabetic patients; however, its molecular mechanism not yet clear, and there no uniform standard for diagnosis. The aim this study to discover the pathogenesis potential therapeutic targets DCM through screening analysis differentially expressed genes (DEGs) heart ventricles DCM, testify role key hub DCM-induced myocardial dysfunction. Datasets GSE4745 GSE6880 were downloaded from GEO database. difference analysis, visual cluster...
Abstract Atypical adenomatous hyperplasia (AAH) and squamous cell dysplasia (SCD) have been widely reported to be associated with the development of malignant lesions in lung. Accurate diagnosis AAH SCD could facilitate earlier clinical intervention also provide useful information for assessing lung cancer risk human populations. Traditionally, detection has achieved by imaging bronchoscopy, but sensitivity remains unsatisfactory. In this study, we utilised ability immune system identify...
Abstract Malignant mesothelioma (MM) survival rate has been hampered by the lack of efficient and accurate early detection methods. The immune system may detect changes tumor progression responding with tumor-associated autoantibody production. Hence, in this study, we translated humoral response to cancer proteins into a valuable blood test for MM. A T7 phage MM cDNA library was constructed using tissues biopanned antigens (TAAs) pooled patients normal serum samples. About 1000 individual...