A5022588790- Astro and Planetary Science
- Radio Frequency Integrated Circuit Design
- Geological and Geochemical Analysis
- Advanced Power Amplifier Design
- Traumatic Brain Injury and Neurovascular Disturbances
- Microwave Engineering and Waveguides
- Planetary Science and Exploration
- Isotope Analysis in Ecology
- Semiconductor Quantum Structures and Devices
- Paleontology and Stratigraphy of Fossils
- Heme Oxygenase-1 and Carbon Monoxide
- Nuclear Physics and Applications
- Intracranial Aneurysms: Treatment and Complications
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pituitary Gland Disorders and Treatments
- Thermal Regulation in Medicine
- S100 Proteins and Annexins
- High-pressure geophysics and materials
- Mineralogy and Gemology Studies
- Geology and Paleoclimatology Research
- Ion channel regulation and function
- Head and Neck Surgical Oncology
- Pharmacology and Obesity Treatment
- Mesoporous Materials and Catalysis
- Hydrocarbon exploration and reservoir analysis
Japanese Red Cross Kochi Hospital
2018
Sanofi (Japan)
2015
Tokyo Medical University
2006-2012
Tokyo Medical University Hachioji Medical Center
2005-2010
Saga University
2008-2010
Japan Science and Technology Agency
2010
Ibaraki University
1983-2007
Kōchi University
2002-2007
Mitsubishi Electric (Japan)
1989-2006
Mitsubishi Electric (Germany)
2000-2004
Human β1,6-N-acetylglucosaminyltransferase V (GnT-V) was expressed by baculovirus-insect cell system, and the purified recombinant enzyme kinetically characterized. The data obtained were used to establish kinetic basis of substrate specificity toward donor nucleotide sugars, also revealed that Km values for donors are much higher compared those other GlcNAc transferases, properties which have been reported. Because this exceptionally suggests GnT-V is physiologically present at far from...
The Y‐7308 howardite comprises a variety of lithic clasts and mineral fragments. Mg/(Mg+Fe) atomic ratios the pyroxenes in diogenitic clasts, eucritic Fayalite‐Hedenbergite‐Tridymite‐Plagioclase vary continuously from 0.76 to less than 0.30. Olivine fragments matrix have wide range 0.88 0.71. This continuum chemical compositions for olivine pyroxene is explained by fractional crystallization primary magma. composition liquid produced removing magma almost identical that eucrites,...
Abstract— Chondrules in the Bali‐like CV chondrite Kaba and Allende‐like portion of Mokoia breccia have been studied to explore relationship between hydrous alteration form phyllosilicates anhydrous resulting secondary olivine zonation, replacement enstatite by ferroan formation feldspathoids (nepheline sodalite). All chondrules experienced extensive alteration; whereas, was minor resulted only zonation. On other hand, all both alteration. Bronzite rims formed relic grains during...
Gitelman's syndrome is a variant of Bartter's syndrome, characterized by hypokalemia, hypomagnesemia, hypocalciuria, and hypovolemia. We have observed familial cases possible mutation in thiazide-sensitive Na-Cl cotransporter was investigated this kindred. The proband 47-yr-old Japanese female, her mother also affected. Her parents maternal grandparents are consanguineous. By using PCR-amplification direct sequencing, we identified novel non-conservative missense at 623 amino acid position,...
Abstract— We petrologically examined the Miller Range (MIL) 03346 nakhlite. The main‐phase modal abundances are 67.7 vol% augite, 0.8 olivine, and 31.5 mesostasis. Among all known nakhlites, MIL 03346's abundance of olivine is smallest mesostasis largest. Augite occurs as cumulus phenocrysts having a homogeneous core composition (En 36–38 Fs 24–22 Wo 40 ), which identical with other nakhlites. They accompany thin ferroan rims divided into inner outer compositional gap at boundary between two...
Human serum paraoxonase (PON1) is associated with high-density lipoprotein, and inhibits oxidative modification of low-density lipoprotein. Therefore, PON1 supposed to contribute the prevention atherosclerosis. We other investigators have shown that enzymatic activities concentrations were decreased in maintenance hemodialysis (HD) patients. However, effect status on long-term outcome HD patients has not been reported. In this study, we examined association between baseline PON 1...
The effects of dimethyl sulfoxide (DMSO) and dimethylthiourea (DMTU) deferoxamine (DFO) were investigated in cats during a standard cortical freezing method for the production vasogenic brain oedema. Hydroxyl radical scavenging activity was studied by electron spin resonance assay using DMPO as trap. hydroxyl adduct extinguished DFO large dose DMTU. Evans blue dye extravasation reduced DMSO treated groups well. appears to be an effective agent prevention cold induced DMTU are direct...
The baculovirus–insect cell expression system is in widespread use for expressing post-translationally modified proteins. As a result, it potentially applicable the production of glycoproteins therapeutic and diagnostic purposes. For practical use, however, remodeling biosynthetic pathway host-cell N-glycosylation required because insect cells produce paucimannosidic glycoforms, which are different from typical mammalian glycoform, due to trimming non-reducing terminal β1,2-GlcNAc residue...
A photon-counting image sensor with 3.36- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu$</tex-math> </inline-formula> m-pitch-pixel front-end (PFE) circuits and single-photon avalanche diodes is presented here. clustered multi-cycle clocked recharging technique an intermediate most-significant-bit readout employed to achieve a 120-dB high dynamic range (HDR) at 150-frames/s imaging 748...
Journal Article Oxidative Damage Due to Copper Ion and Hydrogen Peroxide Induces GlcNAc-Specific Cleavage of an Asn-Linked Oligosaccharide Get access Hironobu Eguchi, Eguchi *Department Biochemistry, Osaka University Medical SchoolSuita, 565-0871 Search for other works by this author on: Oxford Academic PubMed Google Scholar Yoshitaka Ikeda, Ikeda Souichi Koyota, Koyota Koichi Honke, Honke Keiichiro Suzuki, Suzuki †Department Hyogo College MedicineNishinomiya, John M.C. Gutteridge,...
The prototype model of the high efficiency feed-forward amplifier using RF predistortion linearizer and modified Doherty is developed, performance developed examined experimentally. 13.6% with output power 45W achieved under condition that ACLR (Adjacent Channel Leakage Power Ratio) -55 dBc in 3 GPP test method at room temperature +25/spl deg/C. This top level among previously reported amplifiers for cellular base stations. In concerning amplifier, which key component to enhance design its...
An X-band monolithic-microwave integrated-circuit (MMIC) power amplifier with a simplified on-chip temperature-compensation circuit composed of few diodes and resistor are presented in this paper. At first, the operation principle design method have been investigated. The fabricated four-stage MMIC has demonstrated improvement gain variation from 5.5 to 1.3 dB temperature range -10/spl deg/C +80/spl deg/C.
Bilirubin (Bil) is the end product of heme catabolism. The production Bil reflects oxygenase-1 expression in response to oxidative stress various diseases. To assess role as a marker cases brain damage, we measured serum concentrations patients with hemorrhagic stroke. Serum levels total were 20 subarachnoid hemorrhage symptomatic vasospasms and 23 intracerebral hemorrhage; every day for 14 consecutive days. significantly elevated early phases both groups. Moreover, transient elevation was...
Abstract— The Yamato nakhlites, Y-000593, Y-000749, and Y-000802, were recovered in 2000 from the bare icefield around mountains Antarctica, consisting of three independent specimens with black fusion crusts. They are paired cumulate clinopyroxenites. We obtained intercumulus melt composition nakhlites here call it (YIM). YIM crystallized to form augite rims, olivine rims mesostasis phases cumulates. consist two layers: inner outer. crystallization rim drove interstitial into plagioclase...
The aim of the study was to evaluate efficacy and safety once-daily lixisenatide 20 μg as add-on basal insulin with or without sulfonylurea in Asian patients type 2 diabetes mellitus. a subanalysis 159 Japanese from 24-week double-blind GetGoal-L-Asia (NCT00866658) who received placebo. primary endpoint change baseline HbA1c evaluated using analysis covariance. Once-daily significantly reduced mean [least squares difference vs. placebo − 1.1% (− 12 mmol/mol); p<0.0001]. Significantly more...
This paper presents a photon-counting image sensor with $3.36 \mu \mathrm{m} -$pitch pixel front-end circuits and single-photon avalanche diodes (SPADs). A clustered multi-cycle clocked recharging technique intermediate most-significant-bit readout achieves 120-dB high dynamic range (HDR) at 150fps imaging $748 \times 448$ pixels, while reducing the circuit to \mathrm{m}$ pitch. The power consumption is suppressed 104 mW, even 1.2 million incident photons per pixel. prototype demonstrates...
The active integrated antenna (AIA) concept has been realized in the design of amplifier front end, which enables its applications novel adaptive systems. To address problem mismatch between element and amplifier, we present matching renditions both gain impedance noise figure minimum impedance. In addition, application these principles is demonstrated ultra-compact helical AIA receiver end for operation at 2.1 GHz. Amplifier simulation measurements have carried out to confirm procedure. It...
Objective: The value of surgical intervention in the management hypophysitis remains controversial.
beta-1,4-N-Acetylglucosaminyltransferase III (GnT-III) catalyzes the formation of bisecting GlcNAc and plays a regulatory role in biosynthesis N-linked oligosaccharide. In this study, we examined whether glycosyl transfer catalyzed by GnT-III is reversible, and, addition, investigated equilibrium GnT-III-catalyzed reaction. Incubation agalactosyl-bisected biantennary oligosaccharide with presence sufficiently high concentration uridine diphosphate (UDP) resulted conversion bisected into...