- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV-related health complications and treatments
- Adolescent Sexual and Reproductive Health
- Musculoskeletal pain and rehabilitation
- Advanced Causal Inference Techniques
- Reproductive tract infections research
- Statistical Methods and Bayesian Inference
- HIV/AIDS drug development and treatment
- Food Security and Health in Diverse Populations
- HIV Research and Treatment
- Meningioma and schwannoma management
- Sex work and related issues
- Spine and Intervertebral Disc Pathology
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Pharmacological Effects and Toxicity Studies
- Pain Mechanisms and Treatments
- Statistical Methods and Inference
- Pain Management and Opioid Use
- Homelessness and Social Issues
- Spinal Fractures and Fixation Techniques
- Breastfeeding Practices and Influences
- Long-Term Effects of COVID-19
- Pneumocystis jirovecii pneumonia detection and treatment
University of Alabama at Birmingham
2017-2025
Wake Forest University
2024-2025
AIDS United
2023
Drexel University
2019
University of Washington
2019
West Virginia University
2013-2018
Alabama Department of Public Health
2017
University of Alabama
2017
University of California, San Francisco
2014-2016
University of North Carolina at Chapel Hill
2011-2015
To evaluate the spatial accuracy of a rapid interactive method transferring computed tomographic (CT) information between its display on computer screen to source (test object, operating field), multidimensional combined with six-jointed position-sensing mechanical arm was tested Plexiglas model consisting 50 rods varied height and known location, plastic replica skull, and, subsequently, three patients. The median error value image real location 1-2 mm (P > .95), regardless registration...
SARS-CoV-2 causes a wide spectrum of clinical manifestations and significant mortality. Studies investigating underlying immune characteristics are needed to understand disease pathogenesis inform vaccine design. In this study, we examined cell subsets in hospitalized nonhospitalized individuals. patients, many adaptive innate cells were decreased frequency compared with those healthy convalescent individuals, the exception an increase B lymphocytes. Our findings show increased frequencies T...
A subset of COVID-19 patients exhibit post-acute sequelae (PASC), but little is known about the immune signatures associated with these syndromes. We investigated longitudinal peripheral blood samples in 50 individuals previously confirmed SARS-CoV-2 infection, including 20 who experienced prolonged duration symptoms (lasting more than 30 days; median = 74 days) compared had symptom resolution within days. Individuals maintained antigen-specific T cell response magnitudes to spike protein...
Nineteen consecutive patients who had a symptomatic pseudarthrosis after failed anterior cervical arthrodesis were treated by posterior nerve-root decompression and arthrodesis. The indications for the operation radiculopathy in absence of myelopathy evidence on lateral flexion extension radiographs. average duration follow-up was forty-four months (range, twenty-four to fifty-four months). A solid fusion achieved all patients, relieved but one. motor weakness that been present four...
In an attempt to determine the source of cognitive impairment in 106 consecutively admitted patients at Johns Hopkins Chronic Pain Treatment Center, EEG, Wechsler Adult Intelligence Scale, Memory Quotient, and Bender Gestalt tests were administered. Patients receiving benzodiazepines alone demonstrated alterations functioning EEG evidence a sedative effect. narcotics group not medication did show signs impairment. The effects on sleep perception chronic pain, combination with cortical...
<h3>BACKGROUND AND PURPOSE:</h3> There has been a steady progression of case reports and small surgical series that report successful treatment Tarlov cysts with concomitant relief patients9 symptoms improvement in their neurological dysfunction, yet patients are still told these lesions asymptomatic by physicians. The purpose this study was to analyze the efficacy safety intervention 213 consecutive symptomatic treated CT-guided 2-needle cyst aspiration fibrin sealing. <h3>MATERIALS...
The mitochondrion has been implicated in the development of diabetic cardiomyopathy. Examination cardiac mitochondria is complicated by existence spatially distinct subpopulations including subsarcolemmal (SSM) and interfibrillar (IFM). Dysfunction to SSM reported murine models type 2 diabetes mellitus; however, subpopulation-based mitochondrial analyses have not explored human heart. goal this study was determine impact mellitus on function patient. Mitochondrial from atrial appendages...
Abstract Objective Our aim was to conduct a pilot randomized controlled trial of novel cognitive behaviorally based intervention for pediatric PNES called Retraining and Control Therapy (ReACT). Methods Participants were receive either eight sessions ReACT or supportive therapy, participants completed follow‐up visits at 7‐ 60‐days posttreatment. The primary outcome measure frequency 7‐days Eligibility criteria included children with video‐EEG confirmed participant/parent guardian...
Chronic pain is a common condition for which efficacious interventions tailored to highly affected populations are urgently needed. People with HIV have high prevalence of chronic and share phenotypic similarities other populations.
The impact of a rapid peptide nucleic acid fluorescence in situ hybridization (PNA FISH) assay with an antimicrobial stewardship intervention on the treatment Candida infections was studied.The utility implementing PNA FISH hospitalized patients candidemia evaluated by measuring median time to species identification, targeted therapy, and clinical outcomes, including culture clearance, hospital length stay, mortality. Secondary objectives included determining cost-effectiveness assessing...
Background: Chronic pain occurs in up to 85% of persons living with HIV and is commonly treated long-term opioid therapy (LTOT). We investigated the impact chronic LTOT on outcomes. Methods: This was prospective cohort study conducted between July 2015 2016 5 primary care clinics. defined as ≥moderate for ≥3 months Brief Pain Questionnaire. were assessed at an index visit. Suboptimal retention, least one “no-show” care, virologic failure measured over subsequent year. Multivariable logistic...
Introduction: Pre-exposure prophylaxis (PrEP) cannot meaningfully impact the HIV epidemic in United States without improving access to PrEP and reducing disparities among gay, bisexual, other men who have sex with (GBM), especially GBM of color. A patient-centered approach increase options will offer better solutions GBM. We sought understand how prefer current emerging modalities. Methods: conducted a national online survey adult determine preferences for modalities (daily, on-demand,...
To examine the relationship between body mass index (BMI), abdominal adiposity, handgrip strength and physical function in people with HIV (PWH), to explore potential influence of activity (PA) diet on this relationship. Cross-sectional analyses. The PROSPER-HIV Study was conducted at four clinical sites across United States. Eligible participants were antiretroviral therapy had a viral load <200 copies/mL. Measures included: a) strength; b) function, assessed Short Physical Performance...
Eliminating stigmas that harm sexual and gender minorities (SGM) with HIV is necessary to end the epidemic; however, few validated stigma-reducing interventions for healthcare settings exist, even fewer have been evaluated in Spanish-speaking contexts. Finding Respect Ending Stigma around (FRESH) a setting stigma-reduction intervention was adapted tested address intersectional SGM Dominican Republic. Herein, we detail adaptation process present feasibility, acceptability, pre-post...
To determine the relative value of hepatic arterial and portal venous phase helical computed tomographic (CT) scans for tumor detection vascular opacification in patients with pancreatic malignancy.Ninety-five who had or were suspected having disease underwent dual-phase CT. Arterial acquired 20-40 seconds after contrast material administration; scans, 70-100 administration. Three readers independently scored images a blinded fashion presence tumor, lesion attenuation to normal pancreas,...
Thirty-one patients suffering from intractable pain associated with chronic low back syndrome, cancer, and other disorders have been studied after an average of 6 months treatment by electrical stimulation the spinal cord applied using electrodes inserted through a Touhy needle into epidural space. As judged three different subjective rating methods, epidrual successfully relieved otherwise in 23 to 26 31 patients. Reported improvements ability perform various everyday activities,...
Selection due to survival or attrition might bias estimates of racial disparities in health, but few studies quantify the likely magnitude such bias. In a large national cohort with moderate loss follow-up, we contrasted differences 2 stroke risk factors, incident hypertension and left ventricular hypertrophy, estimated by complete-case analyses, inverse probability weighting, survivor average causal effect. We used data on 12,497 black 17,660 white participants enrolled United States...