A5074288567- Smoking Behavior and Cessation
- Chemical Safety and Risk Management
- Cannabis and Cannabinoid Research
- Innovations in Medical Education
- Occupational Health and Safety Research
- Air Quality and Health Impacts
- Medical Education and Admissions
- Metabolism and Genetic Disorders
- Cancer Cells and Metastasis
- Colorectal Cancer Surgical Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Innovative Microfluidic and Catalytic Techniques Innovation
- Phytoestrogen effects and research
- Breast Cancer Treatment Studies
- Liver physiology and pathology
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- ATP Synthase and ATPases Research
- Air Quality Monitoring and Forecasting
- Hydrogen's biological and therapeutic effects
- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Diet, Metabolism, and Disease
University of California, San Diego
2005-2024
University of California System
2023-2024
SENS Research Foundation
2024
Loma Linda University
2008-2010
City of Hope
2009
VA San Diego Healthcare System
2005
Abstract Immuno-oncology has revolutionized cancer treatment by harnessing the immune system to target and eliminate tumors. However, developing effective therapies remains challenging due complexity of tumor microenvironment (TME), which significantly influences development, progression, response therapies1. Traditional preclinical models have provided valuable insights but fail fully replicate dynamic interactions within human TME. Animal often do not recapitulate human-specific responses,...
The coronavirus disease (COVID-19) pandemic has been a source of disruption, changing the face medical education. In response to infection control measures at University California, San Diego, hybrid in-person and recorded preclerkship curriculum was converted completely virtual format. impact this exclusive teaching platform on quality trainee education is unknown.To determine efficacy course, relative traditional teaching, assess supplementary educational material knowledge acquisition.A...
Recent studies have shown that the functions of PTH-related protein (PTHrP) and its derived peptides cannot be attributed solely to PTH/PTHrP receptor binding. The present study focused on identification other proteins might bind PTHrP at cell surface. Using affinity chromatography, we applied extracts cell-surface biotinylated from cancer normal lines over Sepharose beads coupled with different PTHrP-derived peptides. Elution corresponding free peptide revealed a major about 70 kDa was in...
We sought to examine the impact of hospital surgical volume on number nodes harvested and survival in colorectal cancer (CRC). Between January 1994 December 2004, a total 8567 patients with T1, 2, 3, 4 primary tumors N0, N1, or N2 disease were studied. Hospitals stratified into very low (VLV) (<33 cases/year), (LV) (33–56 medium (MV) (57–84 cases/year). Surgery for CRC was performed most commonly at VLV hospitals: 3488 (40.7%) centers versus 2359 (27.5%) LV 2720 (31.7%) MV centers. The...
Portal vein embolization (PVE) has been used to induce hypertrophy in future liver remnants (FLRs) preparation for major hepatic resection. We report our initial experience with PVE and identify potential predictors of unresectability following PVE.Patients primary metastatic malignancies (n = 20) who underwent between 2004 2008 were categorized by surgical resection status clinicopathologic factors compared.The cohort had the histologies: colorectal adenocarcinoma (45%, n 9), hepatocellular...
Replicative errors, inefficient repair, and proximity to sites of reactive oxygen species production make mitochondrial DNA (mtDNA) susceptible damage with time. We explore
Rates of cannabis initiation among teenagers and young adults are increasing. Further, the use various forms (smoked or vaped) with nicotine (dual use) is increasingly common people. The health effects dual lesser known, particularly in context high-potency products across different routes administration, which ominous terms predicting future outcomes. There a long history being associated decreased activity increased snacking, both could portend an risk metabolic cardiovascular disease,...
Objectives Rates of marijuana and tetrahydrocannabinol (THC) initiation among adolescents are increasing rapidly. Further, Dual use marijuana/THC with nicotine is increasingly common in children young adults. Health effects unknown, which ominous terms predicting future health effects. There long history being associated decreased activity increased snacking (the “munchies”), both could portend an risk metabolic cardiovascular disease, particularly when habits begin during formative years....