Tomohiro Higuchi

ORCID: 0009-0007-7766-1498
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Gastroesophageal reflux and treatments
  • Inflammatory Bowel Disease
  • Veterinary medicine and infectious diseases
  • Gastric Cancer Management and Outcomes
  • Microscopic Colitis
  • Colorectal Cancer Screening and Detection
  • Bone Metabolism and Diseases
  • Wireless Power Transfer Systems
  • Medical and Biological Ozone Research
  • Gastrointestinal motility and disorders
  • Energy Harvesting in Wireless Networks
  • Microbial Metabolites in Food Biotechnology
  • Innovative Energy Harvesting Technologies
  • Eosinophilic Esophagitis
  • IL-33, ST2, and ILC Pathways
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Inorganic Chemistry and Materials
  • Job Satisfaction and Organizational Behavior
  • Pathogenesis and Treatment of Hiccups
  • Diverticular Disease and Complications
  • Connective tissue disorders research
  • Superconductivity in MgB2 and Alloys
  • Neurofibromatosis and Schwannoma Cases
  • Esophageal Cancer Research and Treatment

The University of Tokyo
2025

Shinshu University
2021-2024

Hamamatsu University School of Medicine
2019-2023

Japanese Red Cross Medical Center
2022

Ritsumeikan University
2022

Japan Advanced Institute of Science and Technology
1999

Backgrounds/Aims: Vonoprazan (VPZ) is the first clinically available potassium competitive acid blocker. This class of agents provides faster and more potent inhibition than proton pump inhibitors. Most strains Helicobacter pylori are sensitive to amoxicillin. We hypothesized that dual therapy with VPZ amoxicillin would provide sufficient eradication rate for H. infection. To evaluate this, we compared by VPZ/amoxicillin standard triple VPZ/amoxicillin/clarithromycin therapy. Methods:...

10.1159/000502287 article EN Digestion 2019-08-21

Summary Background Vonoprazan (V), a potassium‐competitive acid blocker, has more durable acid‐inhibitory effect as compared with standard‐dose proton pump inhibitors (PPIs) but not been 2‐4 times higher daily PPI doses administered in two divided doses. Aims To evaluate the of V 10/20 mg once‐daily (OD; V10/V20) vs rabeprazole (R) twice‐daily (BID; R20/R40) healthy Japanese volunteers. Methods This multicentre, randomised, open‐label, two‐period, crossover study V10 or V20 R20, R40 using...

10.1111/apt.15641 article EN Alimentary Pharmacology & Therapeutics 2020-01-28

<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Intracranial solitary fibrous tumors (SFTs) and meningiomas are CNS that share similar imaging manifestations but exhibit different clinical behaviors. This study aimed to compare ADC values conventional features, particularly pre-contrast T1-weighted signal intensity, between intracranial SFTs meningiomas. <h3>MATERIALS METHODS:</h3> We retrospectively evaluated 13 patients with pathologically proven 27 who attended our hospital January...

10.3174/ajnr.a8703 article EN American Journal of Neuroradiology 2025-02-17

Abstract We evaluated the association between endoscopic scores of colonic inflammation and fecal calprotectin (FC), immunochemical occult blood test (FIT), C-reactive protein (CRP) in patients with ulcerative colitis (UC). Endoscopic reflecting most severe lesion [maximum Mayo Subscore (M-MES) Ulcerative Colitis Index Severity (UCEIS)] those entire colon [sum MES (S-MES) Colonoscopic (UCCIS)] were evaluated. FC, FIT, CRP measured, their four was 78 complete colonoscopies (66 UC patients)...

10.1038/s41598-021-90558-z article EN cc-by Scientific Reports 2021-06-14

Based on the job demands and resources model, this study assumes that remote work, supervisory behaviours employee crafting are leveraged by work engagement to increase individual goal attainment. This mediating relationship was tested using survey data collected from 500 Japanese workers during COVID-19 pandemic. Multivariate hierarchical regression analyses were conducted separately two groups: who started before pandemic those after. Among post-COVID-19 workers, employees' attainment...

10.1080/13602381.2022.2084848 article EN Asia Pacific Business Review 2022-06-29

Although the usefulness of endoscopic scores, such as Mayo Endoscopic Subscore (MES), Ulcerative Colitis Index Severity (UCEIS), and Colonoscopic (UCCIS), biomarkers fecal calprotectin (FC) for predicting relapse in ulcerative colitis (UC) has been reported, few studies have included scores evaluating entire colon.

10.3748/wjg.v29.i47.6111 article EN cc-by-nc World Journal of Gastroenterology 2023-12-19

RF wireless power transfer (WPT) system enables long-distance of $1 \sim 10 \mathrm{~m}$, eliminating the need for supply wiring to a huge number sensors in loT era. Recently, above \mathrm{~W}$-class receiver circuits (RX) are becoming required short-time battery charging and high-performance sensor nodes. As shown Fig. 12.6.1, RX input $P_{\text {IN }}$ varies significantly $(10 30 \mathrm{dBm})$ depending on distance from TX, output voltage rectifier widely fluctuates accordingly....

10.1109/isscc49657.2024.10454425 article EN 2022 IEEE International Solid- State Circuits Conference (ISSCC) 2024-02-18

Power supply to the sensors in an IoT-era is a major concern because number of are so enormous that environmental loads and costs will be huge if wires used. Also, battery exchange unacceptable many cases. RF wireless power transfer (WPT) system good solution for remote sources with distance longer than few meters. Figure 1 shows 5.7GHz RFWPT its specification considered this work. The TX controlled by beamforming using frequency reduce beam width antenna size. TX-RX ranges from 10m, thus RX...

10.1109/a-sscc53895.2021.9634794 article EN 2022 IEEE Asian Solid-State Circuits Conference (A-SSCC) 2021-11-07

The surface atomic structure of MgCl2 crystalline particles and MgCl2-supported Ziegler catalysts was observed by means high resolution transmission electron microscopy. Step-terrace structures, characteristic the crystal, are found in images particles. observation shows that crystals severely deformed processes catalyst preparation. Due to preparation procedure used changes from amorphous.

10.1002/(sici)1521-3927(19990501)20:5<245::aid-marc245>3.3.co;2-i article EN Macromolecular Rapid Communications 1999-05-01

Plasmacytoid urothelial carcinomas of the bladder are rare, aggressive variants with a poor prognosis. Few reports have described correlation histopathological features multiparametric magnetic resonance imaging findings in local staging plasmacytoid carcinoma. An 82-year-old woman hematuria was referred to our hospital. Magnetic showed diffuse wall thickening, different signal intensities 2 layers-inner and outer. This case suggests that presence thickening varying layers could aid A...

10.1016/j.radcr.2022.03.034 article EN cc-by-nc-nd Radiology Case Reports 2022-04-13

Background The serum N-terminal telopeptide of type I collagen (NTx) is significantly higher in patients with Crohn disease (CD) than healthy individuals and ulcerative colitis. This study aimed to investigate whether an elevated NTx level a risk predictor osteoporosis CD. Methods Based on the femoral Z-score decreased over 2-year period, 41 CD were divided into ΔZ-score &lt;0 group (Z-score decreased) ≥0 did not decrease). predictors decrease examined. Furthermore, we investigated...

10.1371/journal.pone.0250658 article EN cc-by PLoS ONE 2021-04-27

Abstract Regarding longitudinal location, esophageal squamous cell carcinoma (ESCC) frequently develops in the middle esophagus. However, few studies have focused on circumferential location. We examined frequency and characteristics of ESCC lesions resected by endoscopic submucosal dissection (ESD) regarding both locations. retrospectively evaluated 193 ESD-resected lesions. The development histopathological invasion degrees were compared for each Characteristics based location analyzed,...

10.21203/rs.3.rs-3117614/v1 preprint EN cc-by Research Square (Research Square) 2023-07-11

Abstract Background Serum pepsinogen (PG) levels correlate with the degree of gastric mucosal inflammation and atrophy, which cancer risk, in patients infected Helicobacter pylori ( H. ). PG change after eradication , but it is not known if there are corresponding changes mucosa. We examined whether atrophy correlated measured . Methods retrospectively relationship between serum I, II I/II ratios pylori. The before was scored (0, 1, 2) according to Kyoto classification gastritis. Results A...

10.21203/rs.3.rs-42652/v1 preprint EN cc-by Research Square (Research Square) 2020-08-13
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