A5111693192- Folate and B Vitamins Research
- Sepsis Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Hemodynamic Monitoring and Therapy
- Esophageal and GI Pathology
- Glioma Diagnosis and Treatment
- Receptor Mechanisms and Signaling
- Cardiac Arrest and Resuscitation
- Gut microbiota and health
- Sarcoma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Trauma and Emergency Care Studies
- COVID-19 and Mental Health
- Cancer-related gene regulation
- Parathyroid Disorders and Treatments
- Tracheal and airway disorders
- Neurofibromatosis and Schwannoma Cases
- Connexins and lens biology
- Respiratory Support and Mechanisms
- Congenital Heart Disease Studies
- Climate Change and Health Impacts
- RNA modifications and cancer
- Pharmacology and Obesity Treatment
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
Zhongshan Hospital of Xiamen University
2024-2025
Fudan University
2024-2025
Southern University of Science and Technology
2024
Shenzhen Third People’s Hospital
2024
Guangdong Province Women and Children Hospital
2024
Nanchang University
2022
Second Affiliated Hospital of Nanchang University
2022
Sun Yat-sen University
2022
The Seventh Affiliated Hospital of Sun Yat-sen University
2022
First Affiliated Hospital of Zhengzhou University
2014
Background: S-adenosylhomocysteine (SAH) is a risk factor of cardiovascular disease; inhibition SAH hydrolase (SAHH) results in accumulation and induces endothelial dysfunction atherosclerosis. However, the effect mechanism SAHH atherosclerotic calcification still unclear. We aimed to explore role calcification. Methods: The relationship between was investigated patients with coronary Different vivo genetic models were used examine deficiency on Human aortic murine vascular smooth muscle...
S-adenosylhomocysteine (SAH) is a risk factor of cardiovascular diseases and atherosclerosis. However, the causal association between SAH atherosclerosis still uncertain. In present study, heterozygous hydrolase (SAHH+/-) knockout mice were bred with apolipoprotein E-deficient to produce ApoE-/-/SAHH+/- mice. At 8 weeks age, these fed on AIN-93G diets added or without betaine (4 g betaine/100 diet) for weeks. Compared ApoE-/-/SAHHWT mice, SAHH deficiency caused an accumulation plasma...
Prior investigation revealed that elevated serum total homocysteine (tHcy) are strongly correlated with atrial fibrillation (AF) recurrence. Herein, the goal of this study was to elucidate whether folic acid (FA) treatment reduced AF recurrence following radiofrequency catheter ablation (RFCA).To conduct retrospective research, we included consecutive H-type hypertensive patients, who were treated first RFCA, between January 2010 and 2022. We assessed risk patients taking 10 mg enalapril 0.8...
BackgroundWeaning patients from mechanical ventilation is a critical clinical challenge post cardiac surgery. The effective liberation of the ventilator significantly improves their recovery and survival rates. This study aimed to develop validate prediction model evaluate likelihood successful extubation in post-cardiac surgery patients.MethodA predictive nomogram was constructed for success individual patients, receiver operating characteristic (ROC) calibration curves were generated...
Sepsis is a life-threatening condition characterized by an aberrant host response to infection, resulting in multi-organ dysfunction. The application of currently available prognostic indicators for sepsis primary hospitals challenging. In this retrospective study, we established novel index, the neutrophil-to-lymphocyte-to-monocyte ratio (NLMR), based on routine blood examination upon admission, and assessed its value early mortality risk adult patients with septic shock.
The mechanisms behind the high inflammatory state and immunocompromise in severe sepsis remain unclear. While microbiota's role immune regulation is known, impact of pulmonary microbiota on progression not fully understood. This study aims to investigate microbial characteristics septic patients their relationship with host immune-related genes clinical features. Fifty-four were divided into immunocompromised (ICH) group (
Background The spread of COVID-19 has a huge impact on the medical system, affecting normal order routine patients, especially obvious effect Shenzhen Third People’s Hospital as designated hospital for patients. After epidemic was loosened in early December 2022, gradually restored China. How much admission and treatment emergency trauma patients during after epidemic? This study aims to compare differences between admitted department pandemic. Methods findings included all through from...
利拉鲁肽是一种新型的胰升糖素样肽1(glucagon-like peptide-1,GLP-1)类似物,201 1年在我国上市并用于2型糖尿病的治疗,降糖作用显著,但长期心血管安全性尚未证实,近年发现该药可致心率增快,现报道1例如下.患者男性,48岁,因血糖高10年,消瘦8个月,心悸3个月入院,曾在饮食及运动基础上联合应用“二甲双胍、吡格列酮、阿卡波糖及甘精胰岛素30 U”治疗,血糖控制不佳(空腹血糖波动于15.0～17.0 mmol/L)。
Objective To investigate the correlation of plasma levels secreted frizzled related protein 4 with glucose and lipid metabolism islet function in people different tolerance.Methods The SFRP4 60 patients pre-diabetes mellitus group,80 newly diagnosed type 2 diabetes (T2DM group) 80 cases normal control group were detected by ELISA method.Single factor analysis variance method was used to compare levels.The metabolic indexes analyzed.Multiple stepwise regression find out main factors...
Objective To study the change of eonnxin43 expression in heart diabetic mellitus rats. Methods STZ-in-dueed rats were developed. The connexin43 was detected by immunohistochemistry and image analysis, function observed electrophysiolograph echocardiogram. Results During course mellitus, decreased respectively 12th week 24th (P<0.01). values dp/dtmax + group DM lower than that normal control (P<0.01), LVEF also (12w P<0.05,24w P<0.01). analysis correlation showed con-nexin43 positively...