A5091919227- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Inflammasome and immune disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cervical Cancer and HPV Research
- Cardiovascular Function and Risk Factors
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Colorectal and Anal Carcinomas
- Heme Oxygenase-1 and Carbon Monoxide
Xinjiang Medical University
2024-2025
Southern Medical University
2023-2024
Nanfang Hospital
2023-2024
Pulmonary arterial hypertension (PAH) is a chronic disorder characterized by the excessive proliferation of pulmonary smooth muscle cells (PASMCs). Recent studies indicate that Mitochondrial fusion protein 2 (Mfn2) maintains intracellular calcium (Ca2+) homeostasis via mitochondria-associated endoplasmic reticulum membranes (MAMs) pathway, thereby inhibiting PASMCs and reducing artery pressure. However, precise mechanisms remain unclear. This study explored roles Mfn2 IP3R3 in PAH...
The purpose of this study is to develop an animal model Chronic Intermittent Hypoxia (CIH) and investigate the role TRPC5 channel in cardiac damage OSAHS rats. Twelve male Sprague Dawley rats were randomly divided into CIH group Normoxic Control (NC) group. Changes structure, function, pathology heart tissue observed through echocardiography, transmission electron microscopy, HE-staining, TUNEL staining. Interventricular Septum thickness at diastole (IVSd) End-Diastolic Volume (EDV)...
Abstract Background To compare the oncological outcomes of patients with FIGO 2018 stage IIIC cervical cancer (CC) involving different local tumor factors who underwent abdominal radical hysterectomy (ARH), neoadjuvant chemotherapy and surgery (NACT), or chemoradiotherapy (R-CT). Methods Based on staging, were divided into T1, T2a, T2b, T3 groups. Kaplan–Meier Cox proportional hazards regression analysis used to their overall survival (OS) disease-free (DFS) 5 years. Results We included...
Chronic intermittent hypoxia (CIH) is the primary cause of myocardial inflammation in obstructive sleep apnea-hypopnea syndrome (OSAHS). Pyroptosis a newly discovered form programmed cell death accompanying inflammatory reactions. Our previous study showed that TRPC5 upregulated injury CIH rats. The present aimed to explore role CIH-induced pyroptosis.
To identify the cut-off values for number of metastatic lymph nodes (nMLN) and node ratio (LNR) that can predict outcomes in patients with FIGO 2018 IIICp cervical cancer (CC). Patients CC who underwent radical hysterectomy pelvic lymphadenectomy were identified a propensity score-matched (PSM) cohort study. A receiver operating characteristic (ROC) curve analysis was performed to determine critical nMLN LNR values. Five-year overall survival (OS) disease-free (DFS) rates compared using...