A5102990613- Endometrial and Cervical Cancer Treatments
- Pregnancy and preeclampsia studies
- Uterine Myomas and Treatments
- Cancer-related molecular mechanisms research
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- S100 Proteins and Annexins
- Neonatal Respiratory Health Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Renal cell carcinoma treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Birth, Development, and Health
- Surgical site infection prevention
- RNA Research and Splicing
- Chronic Kidney Disease and Diabetes
- Cardiac, Anesthesia and Surgical Outcomes
- Renal and Vascular Pathologies
- Pelvic and Acetabular Injuries
- Angiogenesis and VEGF in Cancer
- Cancer Mechanisms and Therapy
- Assisted Reproductive Technology and Twin Pregnancy
- Frailty in Older Adults
- Fetal and Pediatric Neurological Disorders
- FOXO transcription factor regulation
- Autoimmune Neurological Disorders and Treatments
Baoshan College
2024
Southern Medical University
2013-2023
Nanfang Hospital
2013-2023
The First People's Hospital of Shunde
2021
Foshan University
2021
Abstract Aim: To estimate the incidence of and identify risk factors for a surgical site infection after cesarean section. Method: A survey women who underwent section was conducted in eight hospitals Guangdong Province, China. The rate estimated nested case control study then carried out to factors. Results: Among 13 798 surveyed, 96 (0.7%) developed Multivariate logistic regression analysis identified six independently associated with an increased infection, which included obesity,...
Radical hysterectomy combined with pelvic lymphadenectomy is the standard treatment for early-stage cervical cancer, but unrecognized nerves are vulnerable to irreversible damage during surgery. This early clinical trial investigated feasibility and safety of intraoperative near-infrared (NIR) fluorescence imaging (NIR-FI) indocyanine green (ICG) identifying radical cancer.Sixty-six adults cancer were enrolled in this prospective, open-label, single-arm, single-center trial. NIR-FI was...
A dual prodrug nano-assembled system for synergistic chemotherapy of platinum-resistant ovarian cancer.
Purpose To study the therapeutic effects of uterine artery embolization (UAE) on adenomyosis and to investigate association between blood supply treatment outcomes. Methods Using digital subtraction angiography (DSA) imaging data, we retrospectively evaluated vascular features 252 patients treated with UAE. The cases were classified based equality (equal unequal subgroups) degree vascularity at lesion site (hypervascular, isovascular hypovascular subgroups). Patients followed-up for 5 years...
The abrogation of cAMP generation by overexpression PDE isoforms promotes the inflammatory pathology, and inhibitors have showed potential anti-inflammation effects in clinical. However, function cancer treatment remains unclear. We here investigated role PDE4 inhibitor Roflumilast ovarian cancer. found that could effectively inhibit proliferation, induce apoptosis cell cycle arrest two lines OVCAR3 SKOV3. Meanwhile, cAMP/PKA/CREB signals was activated Roflumilast, which accompanied...
Abstract Objective We previously demonstrated the roflumilast inhibited cell proliferation and increased apoptosis in ovarian cancer. In this study, we aimed to investigate roles of development cisplatin ( DDP )‐sensitive ‐resistant Methods OVCAR 3 SKOV were selected corresponding cells constructed. Cell viability, proliferation, apoptosis, cycle performed. Expression cAMP , PKA CREB phosphorylation FtMt detected. The ‐sensitive cancer confirmed by xenograft model. Results Roflumilast +...
Currently, cisplatin (DDP) is the first-line chemotherapeutic agent used for treatment of ovarian cancer, but gradually acquired drug resistance minimizes its therapeutic outcomes. We aimed to identify crucial genes associated with DDP in cancer and uncover potential mechanisms. Two sets gene expression data were downloaded from Gene Expression Omnibus, bioinformatics analysis was conducted. In our study, differentially expressed between DDP-sensitive DDP-resistant screened GSE15709 GSE51373...
// Gong Shi-Peng 1, * , Chen Chun-Lin Wu Huan 2, Meng Fan-Liang 1 Yong-Ning Zhang Ya-Di Guang-Ping 3 and Cai Ye-Ping 4 Department of Obstetrics Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P.R. China 2 The Second Affiliated Chongqing University Sciences, 400010, People's Hospital Huadu District, 510800, Maternal Child Health Duanzhou Zhaoqing 526000, These authors have contributed equally to the study should considered as co-first Correspondence to: Shi-Peng,...
Abstract Background To compare the oncological outcomes of patients with FIGO 2018 stage IIIC cervical cancer (CC) involving different local tumor factors who underwent abdominal radical hysterectomy (ARH), neoadjuvant chemotherapy and surgery (NACT), or chemoradiotherapy (R-CT). Methods Based on staging, were divided into T1, T2a, T2b, T3 groups. Kaplan–Meier Cox proportional hazards regression analysis used to their overall survival (OS) disease-free (DFS) 5 years. Results We included...
Objective. Heparin was hypothesized to facilitate the growth of growth-restricted fetus. Our study assess efficiency heparin in treating fetus with restriction and explore possible mechanisms.
Introduction: A three-dimensional (3D) model of the pelvic vessels was reconstructed before surgery to aid in understanding individual anatomy and help guide lymphadenectomy performance.Material methods: Thirty patients with early-stage cervical cancer who were scheduled for at Nanfang Hospital, Southern Medical University from January 2017 June included. Three-dimensional models obtained.Results: All 3D 30 successfully consistent operative findings.The most common structural types posterior...
To compare the performance of serum cancer antigen 125 (CA125), human epididymis protein 4 (HE4), Risk Ovarian Malignancy Algorithm (ROMA) and Copenhagen index (CPH-I) for differential diagnosis benign malignant diseases in patients with ovarian mass.We retrospectively analyzed data 719 women pelvic mass, preoperative levels CA125 HE4, ROMA CPH-I masses was compared.Of 710 analyzed, 531 were diagnosed lesions, 44 borderline tumors (BOTs), 119 epithelial cancers (EOCs), 25 non-EOCs. In...
<title>Abstract</title> Background The testis is the primary organ of male reproductive system, responsible for sperm production and androgen secretion. Given complexity spermatogenesis, understanding cellular heterogeneity gene expression in pig essential. However, composition remains poorly understood. Here, we employed both long-read short-read single-cell RNA sequencing on Baoshan to uncover patterns diversity. Results We meticulously discerned mature testicular architecture an orderly...