A5076598667- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Veterinary Pharmacology and Anesthesia
- Nerve injury and regeneration
- Global Cancer Incidence and Screening
- Helicobacter pylori-related gastroenterology studies
- Vagus Nerve Stimulation Research
- Pain Mechanisms and Treatments
- Nerve Injury and Rehabilitation
- Gastrointestinal motility and disorders
- Neurotransmitter Receptor Influence on Behavior
- Breast Cancer Treatment Studies
- Education and Character Development
- Clinical practice guidelines implementation
- Connective tissue disorders research
- Rabbits: Nutrition, Reproduction, Health
- Axon Guidance and Neuronal Signaling
- Marine Invertebrate Physiology and Ecology
- Stress and Burnout Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Meta-analysis and systematic reviews
- Inflammatory mediators and NSAID effects
- Cardiovascular Conditions and Treatments
- Scoliosis diagnosis and treatment
- Breast Lesions and Carcinomas
Communities In Schools of Orange County
2023-2024
University of North Carolina at Chapel Hill
2023-2024
University of North Carolina Health Care
2024
Horizon Health Network
2014-2015
King's College Hospital
1962-1980
University of Cambridge
1974
Royal College of Surgeons of England
1957-1968
University of Aberdeen
1964
Medical Research Council
1964
University College London
1956
Ineffective coping may lead to impaired job performance and burnout, with adverse consequences staff well-being patient outcomes. We examined the relationship between styles burnout in emergency physicians, nurses support at seven small, medium large departments (ED) a Canadian health region (population 500,000).Linear regression Coping Inventory for Stressful Situations (CISS) Maslach Burnout (MBI) was used evaluate effect of style on levels cross-sectional survey 616 ED members. CISS...
Human stomach mucosa contains a pharmacologically active acidic lipid which is indistinguishable from (PGE2) prostaglandin E2 by chromatography in 2 different systems, and other tests. The concentrations present are of the order 1 mcg/g wet tissue. Concentrations similar body pyloric part stomach; much smaller amounts submucosa muscle. PGE2 acts directly on both longitudinal circular muscle layers human isolated stomach. contracted doses may be as low 2x10 -9 g/ml. In contrast, inhibits...
Xylazine is in the unregulated drug supply at increasing rates, usually combined with fentanyl, necessitating understanding of its pharmacology. Despite commentary from politicians, and public health officials, it unknown how xylazine impacts naloxone efficacy, and. few studies have examined alone. Here, we examine impact alone combination fentanyl on several behaviors mice. Surprisingly, precipitates withdrawal fentanyl/xylazine coadministration, enhanced sensitivity females. Further, a...
Division of all vagal branches to the stomach may be important in treatment duodenal ulcer. As long ago as 1947 Dragstedt and his colleagues pointed out that if a branch vagus is inadvertently missed at operation there reactivation whole glandular apparatus, return high acid secretion, consequent recurrence ulc?ration ; more recently Murray (1962a) discussed mechanism nervous activity. In 1958 B?rge Vane introduced method testing for completeness section time operation, Clark (1963)...
EDITORIAL SYNOPSIS The pattern of gastric secretion has been studied in a series patients following the augmented histamine test and insulin test.In same patient, amount acid pepsin secreted is remarkably similar these two tests.In both, inhibited to degree by small doses hexamethonium atropine.It concluded that action causing man not specific one on acidsecreting cells, nor does it act directly upon cells.It suggested acts through nerves.
Abstract Xylazine has been found in the unregulated drug supply at increasing rates, usually combination with fentanyl. It become critical to understand its basic pharmacology, how it impacts behavior, and interacts fentanyl rodent models of opioid administration. Despite commentary from scientists, politicians, public health officials, is not known if xylazine efficacy naloxone, receptor antagonist used reverse induced respiratory depression. Furthermore, few studies have examined effects...
Alcohol use disorders (AUDs) impose an enormous societal and financial burden, world-wide, alcohol misuse is the 7th leading cause of premature death1. Despite this, there are currently only 3 FDA approved pharmacological treatments for treatment AUDs in United States. The neurotensin (Nts) system has long been implicated modulating behaviors associated with misuse. Recently, a novel compound, SBI-553, that biases action Nts receptor 1 (NTSR1) activation, shown promise preclinical models...
tion of the substance under suitable conditions must mimic physiological function.4 In addition, one expects to find that function and induced by injection are affected similarly inhibitory drugs.5 After denervation effector cells become hypersensitive substance.This first paper is concerned with distribution histamine within human stomach.The mechanism secretion discussed in following article (Clark, Curnow, Murray, Stephens, Wyllie, 1964).METHODS MATERIAL Human stomachs were obtained...
The Cancer Research Campaign Trial concerning the management of early breast cancer recruited well over 2000 patients, thus making it largest prospective study on record. such large numbers created specific problems organisation. It is recommended that protocol design and proforma should be kept simple. A centralized secretariat set up, statisticians computer programmers must concerned at every step, including analysis. Large clinical trials are very expensive not embarked without adequate...
Journal Article Cancer research campaign breast study Get access J G Murray Department of Surgery, King's College Hospital Medical School, London Search for other works by this author on: Oxford Academic Google Scholar British Volume 61, Issue 10, October 1974, Pages 772–774, https://doi.org/10.1002/bjs.1800611007 Published: 07 December 2005