Nicole Buono

ORCID: 0009-0007-9176-9972
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • Adolescent Sexual and Reproductive Health
  • Vitamin C and Antioxidants Research
  • Alcoholism and Thiamine Deficiency
  • Global Maternal and Child Health
  • Infectious Encephalopathies and Encephalitis
  • Sex work and related issues
  • Urologic and reproductive health conditions
  • HIV Research and Treatment
  • Genital Health and Disease
  • Viral Infections and Outbreaks Research
  • Female Genital Mutilation/Cutting Issues
  • HIV/AIDS Impact and Responses
  • COVID-19 Impact on Reproduction

United States Agency for International Development
2024

Elizabeth Glaser Pediatric AIDS Foundation
2016

Population Council
2002

Introduction The implementation of lifelong antiretroviral treatment (ART) for all pregnant women (Option B+) in Malawi has resulted a significant increase the number HIV‐positive initiating treatment. However, research highlighted challenge retaining newly initiated care. This study explores barriers and facilitators that affect woman's decision to initiate adhere Option B+. Methods A total 39 in‐depth interviews 16 focus group discussions were conducted. Eligible ≥18 years old, living with...

10.7448/ias.19.1.20919 article EN cc-by Journal of the International AIDS Society 2016-01-01

Pellagra is caused by niacin (vitamin B3) deficiency and patients with pellagra present a characteristic rash. Isoniazid disrupts intracellular synthesis might induce deficiency. In 2017, Malawi scaled up continuous isoniazid preventive treatment (IPT) for tuberculosis prevention among people living HIV. addition, an under-diversified diet based on subsistence maize, as commonly the case in Malawi, risk factor pellagra. We aimed to investigate whether large-scale exposure contributed...

10.1016/s2214-109x(22)00096-1 article EN cc-by-nc-nd The Lancet Global Health 2022-04-12

Background. Identifying and testing all HIV-exposed infants (HEIs) by 2 months of age with rapid antiretroviral therapy (ART) initiation for those infected is critical to survival. Yet in 2009 only 29% HEIs need ART received treatment Malawi. Objectives. To understand barriers, facilitators recommendations five key steps the early infant diagnosis (EIDT) cascade: (1) identification HEIs; (2) testing; (3) sample processing transport; (4) reporting results mothers; (5) HEI. Methods....

10.7196/sajch.2016.v10i2.982 article EN cc-by-nc South African Journal of Child Health 2016-06-29

Background. Identifying and testing all HIV-exposed infants (HEIs) by 2 months of age with rapid antiretroviral therapy (ART) initiation for those infected is critical to survival. Yet in 2009 only 29% HEIs need ART received treatment Malawi. Objectives. To understand barriers, facilitators recommendations five key steps the early infant diagnosis (EIDT) cascade: (1) identification HEIs; (2) testing; (3) sample processing transport; (4) reporting results mothers; (5) HEI. Methods....

10.7196/sajch.2016v10i2.982 article EN South African Journal of Child Health 2016-06-29

Introduction Voluntary medical male circumcision (VMMC), an effective HIV prevention programme for men, is implemented in East and Southern Africa. Approximately 50% of VMMC clients are aged below 15 years. More targeted interventions to reach older men others at higher short-term risk needed. Methods We a quality improvement project testing the effectiveness active referral-based recruitment approach, targeting attending STI clinics those escorting partners antenatal care (ANC) clinics,...

10.1136/sextrans-2020-054776 article EN cc-by-nc Sexually Transmitted Infections 2021-01-04

The early period of the COVID-19 pandemic limited access to HIV services for children and adolescents living with (C/ALHIV). To determine progress in providing care treatment services, we describe viral load coverage (VLC) suppression (VLS) (<1000 copies/ mL) rates during 12 United States President’s Emergency Plan AIDS Relief (PEPFAR)-supported countries. Data (0–9 years) (10–19 on VLC VLS were analyzed sub-Saharan African (SSA) countries between 2019 (pre-COVID-19) 2020 (during...

10.1371/journal.pgph.0003513 article EN public-domain PLOS Global Public Health 2024-08-01

Background: Pellagra is caused by niacin (vitamin B3) deficiency and manifested a distinctive dermatitis. Isoniazid critical for treating tuberculosis globally component of most regimens to prevent tuberculosis. may contribute pellagra disrupting intracellular synthesis. In 2017, Malawian clinicians recognized high incidence pellagra-like rashes after scale-up isoniazid preventive treatment (IPT) people living with HIV (PLHIV). This increase in among PLHIV coincided seasonal period sustained...

10.3389/fpubh.2020.551308 article EN cc-by Frontiers in Public Health 2020-11-26

Transitions between services for continued antiretroviral treatment (ART) during and after pregnancy are a commonly overlooked aspect of the HIV care cascade, but ineffective transitions can lead to poor health outcomes women their children. In this qualitative study, we conducted interviews with 15 key stakeholders from Ministries Health along PEPFAR-supported other in-country non-governmental organizations actively engaged in national programming adult prevention...

10.1371/journal.pone.0260530 article EN public-domain PLoS ONE 2021-12-02
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