A5100398055- Cancer-related gene regulation
- Bone Tissue Engineering Materials
- Mesenchymal stem cell research
- Salivary Gland Disorders and Functions
- Epigenetics and DNA Methylation
- Analog and Mixed-Signal Circuit Design
- CCD and CMOS Imaging Sensors
- Fibroblast Growth Factor Research
- dental development and anomalies
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Oral and Maxillofacial Pathology
- Dental Implant Techniques and Outcomes
- Advanced DC-DC Converters
- Oral microbiology and periodontitis research
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- AI in cancer detection
- Dental Radiography and Imaging
- Dental Research and COVID-19
- Advancements in Semiconductor Devices and Circuit Design
- Periodontal Regeneration and Treatments
- Optical Coherence Tomography Applications
- Advanced Surface Polishing Techniques
- Advanced Memory and Neural Computing
Xidian University
2022-2025
Stomatological Hospital of Chongqing Medical University
2020-2024
Chongqing Medical University
2020-2024
Stomatology Hospital
2020-2023
Lanzhou University
2023
Fudan University
2023
State Key Laboratory of Biotherapy
2023
Nanjing Medical University
2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023
Sichuan University
2023
An accurate diagnosis of deep caries and pulpitis on periapical radiographs is a clinical challenge.A total 844 were included in this study. Of the 844, 717 (85%) used for training 127 (15%) testing three convolutional neural networks (CNNs) (VGG19, Inception V3, ResNet18). The performance [accuracy, precision, sensitivity, specificity, area under receiver operating characteristic curve (AUC)] CNNs evaluated compared. CNN model with best was further integrated parameters to see whether...
Data recovery from monolithic storage devices (MSDs) is in high demand for legal or business purposes. However, the conventional data methods are destructive, complicated, and time-consuming. We develop a robotic-arm-assisted optical coherence tomography (robotic-OCT) non-destructive inspection of MSDs, offering ~7 μm lateral resolution, ~4 axial resolution an adjustable field-of-view to accommodate various MSD sizes. Using continuous scanning strategy, robotic-OCT achieves automated...
Since the microgap between implant and surrounding connective tissue creates pass for pathogen invasion, sustained pathological stimuli can accelerate macrophage-mediated inflammation, therefore affecting peri-implant regeneration aggravate peri-implantitis. As transmucosal component of implant, abutment needs to be biofunctionalized repair gingival barrier. Here, a mussel-bioinspired coating containing tannic acid (TA), cerium minocycline (TA-Ce-Mino) is reported. TA provides pyrogallol...
Abstract Background BMP9-stimulated DPSCs, SCAPs and PDLSCs are effective candidates for repairing maxillofacial bone defects in tissue engineering, while the most suitable seed cell source among these three hDMSCs optimal combination of type BMP9 have rarely been explored. Moreover, orthotopic defect model should be valuable but laborious time-consuming to evaluate various regeneration. Thus, inspired from traditional vivo ectopic systems, we developed an intrabony repair recapitulate...
Abstract Objectives Mouse incisor mesenchymal stem cells (MSCs) have self‐renewal ability and osteo/odontogenic differentiation potential. However, the mechanism controlling continuous of mouse MSCs remains unclear. Special AT‐rich sequence‐binding protein 2 (SATB2) positively regulates craniofacial patterning, bone development regeneration, whereas SATB2 deletion or mutation leads to craniomaxillofacial dysplasia delayed tooth root development, similar morphogenetic (BMP) loss‐of‐function...
Introduction Periapical alveolar bone loss is the common consequence of apical periodontitis (AP) caused by persistent local inflammation around area. Human stem cells from papilla (hSCAPs) play a crucial role in restoration lesions during AP. Studies have recently identified critical microRNAs (miRNAs) involved AP pathogenesis, but little known about their function and potential molecular mechanism, especially osteogenesis hSCAPs Here, we investigated clinical sample-based specific miRNAs...
Dental mesenchymal stem cells (MSCs) are recognized as a critical factor in repair of defective craniofacial bone owing to the multiple differentiation potential, ability regenerate distinct tissues, and advantage that they can be easily obtained by relatively noninvasive procedures. Special AT-rich sequence-binding protein 2 (SATB2) is nuclear matrix protein, involved chromatin remodeling transcriptional regulation, has been reported positive regulator osteoblast differentiation, formation,...
The submandibular gland (SMG) and the sublingual (SLG) are two of three major salivary glands in mammals. In mice, they adjacent to each other open into oral cavity, producing saliva lubricate mouth aid food digestion. Though dysfunction accompanied with fibrosis metabolic disturbance is common clinic, in-depth mechanistic research lacking. Currently, on how rescue function challenging, as it must resort using terminally differentiated acinar cells or precursor unknown differentiation. this...
An ultra-low quiescent current output-capacitor-less low dropout (OCL-LDO) regulator for power-sensitive applications is proposed in this paper. To improve the gain of OCL-LDO feedback loop, error amplifier employs a combination cross-coupled input stage boosting equivalent transconductance and negative resistance technique to gain. Meanwhile, order address issue transient response OCL-LDO, sub-threshold slew-rate enhancement circuit paper, which consists signal increase branch. The...
Abstract Skin wound healing is a well‐coordinated process in which various cells and factors participate, during fibroblast exhibits critical role by exerting its multiple activities, including proliferation, migration, invasion, differentiation. Previous studies have identified that fibromodulin (FMOD) could enhance dermal promoting skin but little known about upstream regulator. We occasionally found FMOD expression was downregulated transforming growth factor‐β1 treatment. It hypothesized...
Oral microbial homeostasis is a key factor affecting oral health, and saliva plays significant role in maintaining homeostasis. The submandibular gland (SMG) sublingual (SLG) together produce the most at rest. Organic ingredients, including antimicrobial proteins, are rich distinctive depend on type of acinar cells SMG SLG. However, functions SLG have been difficult to identify distinguish, given their unique anatomical structures. In this study, we independently removed either or from mouse...
Oral and maxillofacial bone defect repair in patients remains challenging clinical treatment due to the different morphologies of defects. An injectable hydrogel microspheres with sustained morphogenetic protein 9 (BMP9) expression for oral has been developed. This study is bioinspired by substantial osteogenesis property recombinant adenoviruses expressing (Ad-BMP9) minimally invasive injection. A novel scaffold encompassing mesenchymal stem cells (BMSCs) transfected Ad-BMP9 was produced...