In March and October 2015, the Drug Enforcement Administration (DEA) CDC issued nationwide alerts identifying fentanyl, particularly illicitly manufactured fentanyl (IMF), as a threat to public health safety (1,2). IMF is pharmacologically similar pharmaceutical (PF), but unlawfully produced in clandestine laboratories, obtained via illicit drug markets, includes analogs. Fentanyl synthetic opioid 50-100 times more potent than morphine approved for management of surgical/postoperative pain,...

In 2012, approximately 40,000 suicides were reported in the United States, making suicide 10th leading cause of death for persons aged ≥16 years (1). From 2000 to rates among this age group increased 21.1%, from 13.3 per 100,000 16.1 To inform prevention efforts, CDC analyzed by occupational group, ascribing codes 12,312 17 states 2012 National Violent Death Reporting System (NVDRS) (2). The frequency different groups was examined, and calculated sex these categories. Persons working...

Background Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease affecting various organs with wide range of clinical manifestations. Cutaneous (CLE) can manifest as feature SLE or an independent skin ailment. Health-related quality life (HRQoL) frequently compromised in individuals living lupus. Understanding patients’ perspectives when crucial for effectively meeting their unmet needs. Social listening promising new method that provide insights into the...

In this study, we examined whether or not exposure to a humorous surround campaign in Iowa (United States) could produce multiplicative effect based on Intermedia Theory. Until You’re Ready, AvoidtheStork.com © was designed prevent unintended pregnancies among young women. the case of pregnancy, interpersonal sharing is important because women’s contraceptive decisions are influenced by what others, including their friends, think about health issue. sample college students ( n = 594),...

Unintended pregnancy among women in the 18-30 age group is a public health concern. The Extended Parallel Process Model (EPPM) provides framework for exploring how women's perceptions of threat, efficacy, and fear influence intentions to use contraceptives. Past communication with best friends partners were also considered. A telephone survey 18-30-year-old (N = 599) was completed. After univariate bivariate analyses conducted, variables entered into hierarchal, multi-variate linear...

Despite high rates of unintended pregnancy among women aged 18 to 30 years, little research has been conducted understand the factors associated with their contraceptive use. Eighteen focus groups were young adult (N = 106) who mostly white, non-Hispanic. Results suggested that use was negatively affected by low knowledge; alcohol; a lack planning for sex; misperception likelihood pregnancy; forgetting contraceptives; and concerns about side effects, cost, confidentiality. Women liked peace...

In the United States, abusive head trauma (AHT) is one of leading causes maltreatment fatalities among infants and children, accounting for approximately third these deaths (1). Monitoring trends in AHT evaluating prevention strategies have historically been difficult because differences definitions used research surveillance. CDC's case definition data from National Vital Statistics System were to examine fatal during 1999-2014 using Joinpoint trend analysis software. During this period,...

Objectives: Limited studies have examined the usefulness of syndromic surveillance to monitor emergency department (ED) visits involving suicidal ideation or attempt. The objectives this study were (1) examine whether chief complaint data can detect suicide-related ED among adults and (2) assess added value using hospital on discharge diagnoses visits. Methods: came from District Columbia electronic system, which provides daily information at 8 hospitals in Washington, DC. We detected by...

Patients' increasing digital participation provides an opportunity to pursue patient-centric research and drug development by understanding their needs. Social media has proven be one of the most useful data sources when it comes a company's potential audience drive more targeted impact. Navigating through ocean information is tedious task where techniques such as artificial intelligence text analytics have effective in identifying relevant posts for healthcare business questions. Here, we...

<ns3:p><ns3:bold>Background.</ns3:bold> Determining the public health impact of tobacco harm reduction strategies requires assessment consumer perception and behavior associated with nicotine products (TNPs) different exposure risk profiles. In this context, rigorous methods to develop validate psychometrically sound self-report instruments measure consumers’ responses TNPs are needed.</ns3:p><ns3:p> <ns3:bold>Methods.</ns3:bold> Consistent best practice guidelines, including U.S. Food Drug...

Web sites about sexual health lack the interactivity, humor, and “viral” nature required to attract young adults. The Midwest Teen Sex Show (www.midwestteensexshow.com) is an interactive, humor-based site that provides information One episode from was shown six focus groups of women, ages 18–30. Women found it funny, but some were offended or confused. unable differentiate between facts humor; however, women could identify key messages. Most reported they would think later, visit site, share...

Although research advocates for comprehensive cross sector youth violence prevention efforts, mobilizing across sectors to translate scientific recommendations into practice has proven challenging. A unifying framework may provide a foundational step towards building shared understanding of the risk and protective factors that impact violence. We conducted two empirical tests nurturing environment on ethnic geographically diverse rural urban adolescent samples. Results show overall...

<title>Abstract</title> Purpose Patient-reported measures of overall side effect burden, such as the Functional Assessment Cancer Therapy- item GP5 (GP5), can be used to inform tolerability cancer treatments and included an endpoint in clinical trials. The objectives this qualitative study were explore how participants with medullary thyroid (MTC) conceptualize bother, generate evidence support a fit-for-purpose measure patient-reported treatment MTC establish which response options...

This article examines the opportunities and benefits of artificial intelligence (AI)-enabled social media listening (SML) in assisting successful patient-focused drug development (PFDD). PFDD aims to incorporate patient perspective improve quality, relevance, safety, efficiency evaluation. Gathering perspectives support is aided by participation groups communicating their treatment experiences, needs, preferences, priorities through online platforms. SML a method gathering feedback directly...

Abstract Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with heterogeneous clinical manifestations which significantly impacts the daily lives of patients. Herein, we aimed to (i) investigate patients’ perspectives on and experience SLE; (ii) identify meaningful aspects health (MAHs) concepts interest (COIs) in SLE that could be evaluated using digital measures (DCMs); (iii) target DCMs for their assessment. Methods A mixed-methods, multistep approach was...

<sec> <title>UNSTRUCTURED</title> Patient-focused drug development (PFDD) aims to incorporate the patient perspective improve quality, relevance, safety, and efficiency of inform evaluation. Gathering perspectives support PFDD has become more feasible with increased digital presence participation groups that communicate their treatment experiences, needs, preferences, priorities through online forums. Social media listening (SML) is a method gathering substantial amount feedback directly...