A5100980717- Natural Language Processing Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Topic Modeling
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Medical Imaging and Pathology Studies
- Crystal structures of chemical compounds
- Esophageal and GI Pathology
- Clinical Nutrition and Gastroenterology
- Microbial Community Ecology and Physiology
- Statistical Methods in Clinical Trials
- Multi-Criteria Decision Making
- Advanced Text Analysis Techniques
- Ureteral procedures and complications
- Amyotrophic Lateral Sclerosis Research
- Ferroptosis and cancer prognosis
- Crystallization and Solubility Studies
- Liver Disease Diagnosis and Treatment
- Signaling Pathways in Disease
- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Pleural and Pulmonary Diseases
- Cancer Risks and Factors
- Kidney Stones and Urolithiasis Treatments
- Enhanced Recovery After Surgery
- Algorithms and Data Compression
Southern Medical University
2023-2025
Minzu University of China
2024
Zhengzhou University
2016-2024
Henan Cancer Hospital
2016-2024
Nanjing University
2023
Taizhou Second People's Hospital
2022
Nanjing University of Science and Technology
2022
Dalian University of Technology
2013-2015
Wuhan University
2012
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy derived from parafollicular cells (C cells) of the thyroid. Here we presented comprehensive multi-omics landscape 102 MTCs through whole-exome sequencing, RNA DNA methylation array, proteomic and phosphoproteomic profiling. Integrated analyses identified BRAF NF1 as novel driver genes in addition to well-characterized RET RAS proto-oncogenes. Proteome-based stratification revealed three molecularly heterogeneous subtypes...
The proportional hazards (PH) assumption is often violated in clinical trials. If the most commonly used Log-rank test for trial design non-proportional hazard (NPH) cases, it will result power loss or inflation, and effect measures ratio become difficult to interpret. To circumvent issue caused by NPH make easy interpret communicate, two simulation-free methods about restricted mean survival time group sequential (GS-RMST) are introduced this study: independent increment GS-RMST (GS-RMSTi)...
Abstract Objective To evaluate the safety, clinical efficacy, and long‐term outcome of arsenic trioxide (As 2 O 3 ) intravenous infusion for pulmonary metastases in patients with HCC. Materials Methods Sixty consecutive who were diagnosed advanced hepatocellular carcinoma (HCC) metastasis randomized 1:1 into treatment control groups. Treatment group underwent transcatheter arterial chemoembolization (TACE) primary liver tumor then As treatment, whereas TACE alone. The a continuous 5‐h 10...
This study investigated the feasibility, safety, and efficacy of transarterial chemoembolization (TACE) combined with CT-guided 125iodine seed implantation for treatment hepatocellular carcinoma (HCC) first-branch portal vein tumor thrombosis (PVTT).This prospective, controlled, multicenter included HCC patients Barcelona Clinic Liver Cancer stage C disease PVTT in right and/or left veins. Patients were treated either TACE sorafenib or regularly evaluated clinical response adverse events,...
Background/Aims: Gastric cancer is a highly aggressive tumor containing stem cells (CSCs), which participate in initiation, therapeutic resistance, and relapse. Proline-rich protein 11 (PRR11) has been shown to be up-regulated human cancers; however, its role gastric CSCs unknown. We hypothesize that PRR11 may affect tumorigenicity of CSCs. In this study, we explored the biological function regulation Methods: Expression was evaluated CSC cell line by real-time quantitative PCR western blot....
Background Patients with early-stage breast cancer may have a higher risk of dying from other diseases, making competing risks model more appropriate. Considering subdistribution hazard ratio, which is used often, limited to assumptions and clinical interpretation, we aimed quantify the effects prognostic factors by an absolute indicator, difference in restricted mean time lost (RMTL), intuitive. Additionally, dynamic (time-varying effects) long-term follow-up. However, existing regression...
// Hong Tao Hu 1 , Jun Peng Luo Hai-Liang Li Chen Yang Guo Quan Yao Xiang Geng Jiang Department of Radiology and Research Institute Radiology, The Affiliated Cancer Hospital Zhengzhou University, Henan Hospital, Zhengzhou, Province 450003, P. R. China Correspondence to: Li, email: irlihailiang@163.com Keywords: hepatocellular carcinoma, portal vein tumor thrombus, transarterial chemoembolization, 125 iodine implantation, computed tomography-guided Received: October 11,...
Ultrafast lasers in the true-green spectrum, which are scarce due to "green gap" semiconductor materials, high demand for surging field of biomedical photonics. One ideal candidate efficient green lasing is Ho:ZBLAN fiber, as ZBLAN-hosted fibers have already reached picosecond dissipative soliton resonance (DSR) yellow. When attempting push DSR mode locking further into green, traditional manual cavity tuning faced with extreme difficulty, emission regime these fiber so deeply concealed....
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting motor neurons, with broad heterogeneity in progression and survival different patients. Therefore, an accurate prediction model will be crucial to implement timely interventions prolong patient time.A total of 1260 ALS patients from the PRO-ACT database were included analysis. Their demographics, clinical variables, death reports included. We constructed dynamic Cox through landmarking approach. The predictive...
Purpose: To compare the efficacies of transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) hepatectomy. Prognostic factors for patient groups were analyzed. Patients and methods: Data 314 newly diagnosed cases hepatocellular carcinoma beyond Milan criteria studied from January 2012 to December 2013 in our hospital. Forty-four patients excluded owing loss follow-up (27 cases) or missing imaging data (17 cases); finally, 270 included. All underwent TACE RFA (TR...
The purpose of this study was to use serial magnetic resonance imaging (MRI) examinations observe changes in malignant lung tumors over time post-cryoablation. protocol approved by Institutional Review Board, and written informed consent obtained from each participant accordance with the Declaration Helsinki. Patients primary or metastatic eligible for cryoablation were included prospective study. Cryoablation performed according standard procedures. Unenhanced dynamic contrast-enhanced MRI...
Abstractive summarization is the process of generating a summary given document as input. Although significant progress has been made, factual inconsistency between and generated still limits its practical applications. Previous work found that probabilities assigned by generation model reflect preferences for summary, including preference consistency, language or knowledge prior well. To separate we propose an unsupervised framework named CoP controlling with help prompt. More specifically,...
Though reasoning abilities are considered language-agnostic, existing LLMs exhibit inconsistent across different languages, e.g., in the dominant language like English is superior to other languages due imbalance of multilingual training data. To enhance non-dominant we propose a Multilingual-Alignment-as-Preference Optimization framework (MAPO), aiming align processes with language. Specifically, harness an off-the-shelf translation model for consistency between answers and which adopt as...
It is not uncommon for a substantial proportion of patients to be cured (or survive long-term) in clinical trials with time-to-event endpoints, such as the endometrial cancer trial. When designing trial, mixture cure model should used fully consider fraction. Previously, sample size calculations were based on proportional hazards assumption latency distribution between groups, and log-rank test was deriving formulas. In real studies, distributions two groups often do satisfy assumptions....
Abstract C 35 H 38 N 2 O 8 , monoclinic, P 1 (no. 4), a = 14.0502(3) Å, b 5.93007(14) c 18.3417(4) β 101.327(2)°, V 1498.45(6) Å 3 Z 2, R gt ( F ) 0.0443, w ref 0.1082, T 100(2) K.
Hong-Tao Hu, Hang Yuan, Chen-Yang Guo, Quan-Jun Yao, Xiang Geng, Cheng, Jun-Li Ma, Yan Zhao, Li Jiang, Yu-Qing and Hai-Liang Li. Int J Gastrointest Interv 2021;10:67-71. https://doi.org/10.18528/ijgii210007
To retrospectively evaluate the efficacy and safety of local ablation treatment for adjacent pleural lung tumors.Sixty-two patients who underwent pulmonary nodule at Affiliated Cancer Hospital Zhengzhou University were enrolled between January 2016 December 2020. All followed up with enhanced computed tomography or magnetic resonance imaging within 48 h after 2, 4, 6, 9, 12 months treatment. least months.A total 84 targeted tumors (62 patients) 94 ablations. In 12-month follow-up images, 69...
Background: Evidence of altered brain functional activation in response to different tasks has been reported some peripheral neuropathies. The aim this study was investigate possible central nervous system modifications using task-state Functional Magnetic Resonance Imaging (FMRI) Charcot–Marie–Tooth patients.
To identify the factors related to effectiveness of retrograde removal double J ureteral stents using a simple snare technique in female patients.It was retrospective observational study. From 2012 2017, 128 patients underwent fluoroscopy-guided, stent with or without replacement technique. The position tip urinary bladder classified according types A, B, C, and D, corresponding ipsilateral lateral, medial, contralateral lateral quadrants bladder, respectively. influencing fluoroscopy time...
To determine the safety and efficacy of microsphere embolization plus transarterial infusion chemotherapy for treatment gastroesophageal junction cancer with hepatic metastasis.Sixty patients metastasis were randomly divided into two groups: group A (treatment group), which was treated cancer, chemoembolization metastasis; B (control metastasis. The regimen used consisted oxaliplatin FUDR. agent Embosphere ultra-liquefied lipiodol, respectively.The median survival time in 19 months, rates at...