Jingyu Lin

ORCID: 0009-0008-3259-5498
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About
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Research Areas
  • Ubiquitin and proteasome pathways
  • Microtubule and mitosis dynamics
  • Cancer-related Molecular Pathways
  • Cell death mechanisms and regulation
  • Protease and Inhibitor Mechanisms
  • Histone Deacetylase Inhibitors Research
  • interferon and immune responses

Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024

FBXO28 is a member of F-box proteins that are the substrate receptors SCF (SKP1, CULLIN1, protein) ubiquitin ligase complexes. Despite implications its role in cancer, function epithelial-mesenchymal transition (EMT) process and metastasis for cancer remains largely unknown. Here, we report critical negative regulator migration, invasion human hepatocellular carcinoma (HCC) vitro vivo. expression upregulated epithelial cell lines relative to mesenchymal counterparts. Mechanistically, by...

10.1038/s41388-023-02809-0 article EN cc-by Oncogene 2023-08-18
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