A5101566625- Nanoplatforms for cancer theranostics
- Robotic Locomotion and Control
- Biomimetic flight and propulsion mechanisms
- Luminescence and Fluorescent Materials
- Sports Dynamics and Biomechanics
- Microfluidic and Bio-sensing Technologies
- Advanced Sensor and Energy Harvesting Materials
- Sulfur Compounds in Biology
- Molecular Sensors and Ion Detection
- Metal-Organic Frameworks: Synthesis and Applications
- Inflammatory Bowel Disease
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
- Cancer Genomics and Diagnostics
- Electrochemical sensors and biosensors
- Advanced Materials and Mechanics
- Cancer Cells and Metastasis
- Gut microbiota and health
- Robotic Path Planning Algorithms
- Viral Infectious Diseases and Gene Expression in Insects
- Cancer Research and Treatments
- Microbial Inactivation Methods
- Developmental Biology and Gene Regulation
- Nonlinear Optical Materials Studies
- Viral-associated cancers and disorders
Hong Kong University of Science and Technology
2023-2025
University of Hong Kong
2023-2025
Tongji University
2024
Shanxi Agricultural University
2022-2024
Lanzhou University
2024
Lanzhou University Second Hospital
2024
Shanghai Tenth People's Hospital
2024
Health Economics and Outcomes Research (United Kingdom)
2022-2023
Australia and New Zealand Banking Group
2023
Xiangtan University
2020-2022
Diabetes is one of the metabolic diseases marked by hyperglycemia and often accompanied occurrence some complications. As a biomarker oxidative stress, hydrogen peroxide (H2O2) has close association with development diabetes its Unfortunately, there no fluorescent probe reported for imaging H2O2 in diabetic mice. Here, novel near-infrared (NIR) named QX-B was designed synthesized to detect H2O2. For probe, quinolinium-xanthene dye used as fluorophore borate ester chosen response group. After...
Hydrogen sulfide (H2S) is an important endogenous gas signal molecule in living system, which participates a variety of physiological processes. Very recent evidence has accumulated to show that H2S closely associated with various cancers and can be regarded as biomarker cancer. Herein, we have constructed new near-infrared fluorescent probe (DCP-H2S) based on isophorone-xanthene dye for sensing hydrogen (H2S). The shows remarkable NIR turn-on at 770 nm large Stokes shift 200 nm, together...
This review will cover the recent advances in label-free approaches to isolate and manipulate circulating tumor cells (CTCs). In essence, do not rely on antibodies or biological markers for labeling of interest, but enrich them using differential physical properties intrinsic cancer blood cells. We discuss technologies that based their biomechanical electrical properties. Label-free analyze CTCs have been recently invoked as a valid alternative “marker-based” techniques, because classical...
We presented an antibiotic-loaded γ-cyclodextrin metal-organic framework that delivered antibiotics suitable for the treatment of bacterial infections. The was developed using and potassium ion via ultrasonic method. antibiotic (florfenicol enrofloxacin) primarily encapsulated into pore structures γ-CD-MOF, which allowed sustained release over extended period time in vitro vivo. Notably, antibiotics-loaded γ-CD-MOF showed much superior activity against bacteria than free (lower MIC value)...
Laser-induced graphene (LIG) has been systematically investigated and employed because of the spartan laser synthesis functional three dimensional (3D) foam-like structures. However, thermally induced deformation during processing is generally undesirable and, therefore, strictly suppressed. This work introduces a novel laser-guided self-assembly approach integrated into fabrication LIG to generate multiscale 3D foam structures in single step. Leveraging photothermal effects ablation on...
Cancer is a major public health problem worldwide, and traditional chemotherapy or single therapeutic strategy often fails to achieve expected results in cancer treatment. Thus, the development of method realize controlled drug delivery synergistic therapy required. Herein, MOF-based nanoparticles named RhI-DOX-GOD@ZIF-90 are synthesized using RhI (a near-infrared fluorescent dye), DOX (an anti-cancer drug) GOD (glucose oxidase). encapsulated inside ZIF-90 framework loaded on surface ZIF-90....
Effective radiation treatment (RT) for recurrent nasopharyngeal cancers (NPC), featuring an intrinsic hypoxic sub-volume, remains a clinical challenge. Lack of disease‐specific in-vitro models NPC, together with difficulties in establishing patient derived xenograft (PDX) models, have further hindered development personalized therapeutic options. Herein, we established two NPC organoid lines from PDX and characterized compared these original tumors using RNA sequencing analysis. Organoids...
Abstract A portable sweat urea sensing system is a promising solution to satisfy the booming requirement of kidney function tele‐monitoring. However, complicated manufacturing route and cumbersome electrochemical testing still need be improved develop point‐of‐care (POCT) tele‐monitoring devices. Here, universal technical based on high‐throughput automatic laser printing strategy for fabricating integrated monitoring proposed. This includes high‐performance laser‐printed electrode, planar...
Gastric cancer is a deadly disease. Some microRNAs are involved in tumor invasion and metastasis. Underexpression of miR-375 has been correlated with tumorigenesis, treatment resistance, poor prognosis. In this study, we first analyzed the profiles prognostic values expression gastric tissues from public database, level samples cell lines was then by quantitative real- time polymerase chain reaction. Significant underexpression seen all compared to paired paracarcinoma tissues, negatively...
It is urgently needed to develop novel adjuvants for improving the safety and efficacy of vaccines. Metal-organic frameworks (MOFs), with high surface area, play an important role in drug delivery. With perfect biocompatibility green preparation process, γ-cyclodextrin metal-organic framework (γ-CD-MOF) fabricated cyclodextrin potassium suitable antigen In this study, we modified γ-CD-MOF span-85 fabricate SP-γ-CD-MOF as animal vaccine adjuvants. The ovalbumin (OVA) model was encapsulated...
Abstract Advanced manufacturing techniques offer tremendous potential in electronics, photonics, and biomedicine. Self‐assembly is a powerful strategy for creating three‐dimensional (3D) artificial structures, but existing thin film release have limitations the relatively complex processes. Herein, localized laser scribing proposed to guide self‐assembly of two‐dimensional films into 3D microstructures. It revealed that laser‐induced heating momentum can roll them various Uniquely, this...
As an endophytic fungus, the growth-promoting effects of Piriformospora indica have been widely confirmed in many its host plants. In this study, we investigated influences P. colonization on growth daughter plants two strawberry cultivars, ‘Benihoppe’ and ‘Sweet Charlie.’ The results showed that fungus significantly promoted both varieties. Its greatly improved almost all parameters plants, including above-ground fresh weight, dry root plant height, petiole length, leaf area, number roots...
Abstract Background Community-acquired pneumonia (CAP) patients with chronic obstructive pulmonary disease (COPD) have higher severity and mortality compared to those without COPD. However, deep investigation into microbiome distribution of lower respiratory tract CAP or COPD was unknown. Methods So we used metagenomic next generation sequencing (mNGS) explore the differences between two groups. Results Thirty-six 11 cases were retrieved. Bronchoalveolar lavage fluid (BALF) collected...
ABSTRACT Resistance to glucocorticoid (GC) treatment in some patients with idiopathic nephrotic syndrome (INS) is a significant clinical problem. Heat shock protein 90 (HSP90) the chaperon of GC receptor, which supposed be key factor response. Therefore, we conducted this study define mechanisms resistance related HSP90. INS and cell lines differing responses were included present study. We found that level HSP90 mRNA expression was significantly higher than healthy controls GC-resistant...
A novel theranostic probe called CX-B-DF is constructed for chemotherapy guided by near-infrared (NIR) fluorescence imaging. Moreover, the accuracy of drug release improved under dual activation (H 2 O and TP).