About
Contact & Profiles
A5106109549
Research Areas
- Asthma and respiratory diseases
- T-cell and B-cell Immunology
- Mast cells and histamine
University of Zurich
2024
Summary After the primary response, circulating memory CD4 + T effector and regulatory cells (Treg) regulate recall responses, which are impaired in allergy. Using mass spectrometry, we discovered distinct metabolomes of these humans their unique enrichment amino acids. By assessing energy metabolism vitro ex vivo single-cell analyses, determined that increased intracellular L-phenylalanine boosts glycolysis while limiting OXPHOS T, Th2, but not Treg cells. also restrains proliferation an...
10.1101/2024.07.29.605231
preprint
EN
bioRxiv (Cold Spring Harbor Laboratory)
2024-07-29
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