A5050401546- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Dark Matter and Cosmic Phenomena
- Computational Physics and Python Applications
- Cosmology and Gravitation Theories
- Neutrino Physics Research
- Atomic and Molecular Physics
- Nuclear physics research studies
- Astrophysics and Cosmic Phenomena
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Chemical Physics Studies
- Black Holes and Theoretical Physics
- Particle Accelerators and Free-Electron Lasers
- Atomic and Subatomic Physics Research
- Radiation Detection and Scintillator Technologies
- Nuclear Physics and Applications
- Quantum, superfluid, helium dynamics
- Distributed and Parallel Computing Systems
- Noncommutative and Quantum Gravity Theories
- Optical properties and cooling technologies in crystalline materials
- Big Data Technologies and Applications
- Cold Atom Physics and Bose-Einstein Condensates
- Particle accelerators and beam dynamics
University of Colorado System
2021-2025
University of Colorado Boulder
2019-2025
Incyte (United States)
2025
Cornell University
2023
Abdelmalek Essaâdi University
2014-2022
Ecole Mohammadia d'Ingénieurs
1993-2008
École Nationale de Commerce et de Gestion de Tanger
1999-2003
ETH Zurich
1988-1995
The inhibition of mutant KRAS proteins has emerged as a promising approach for treating KRAS-driven cancers, evidenced by the clinical success G12C inhibitors. G12D, most common mutant, promises significant expansion addressable patient population; however, reduced nucleophilicity aspartate compared to cysteine poses challenges in balancing sufficient potency with ADME properties support oral exposure. Herein, we describe discovery G12D inhibitor 23 (INCB159020), which achieves exposure...
The $3p\ensuremath{-}1s$ x-ray line of pionic hydrogen was measured with a reflecting bent crystal spectrometer. strong interaction energy level shift and the total decay width $1s$ state, obtained from transition linewidth, are ${\ensuremath{\varepsilon}}_{1s}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}\ensuremath{-}7.127\ifmmode\pm\else\textpm\fi{}0.028\left(\mathrm{stat}\right)\ifmmode\pm\else\textpm\fi{}0.036(\mathrm{syst})\phantom{\rule{0ex}{0ex}}\mathrm{eV}$ (attractive)...
ABSTRACT: Despite the Organization of African Unity (OAU) and its successor, Union (AU), upholding inviolability colonial borders, South Sudan successfully seceded from in 2011. In contrast, Katanga’s earlier attempt to secede Congo during 1960s failed. Both cases highlight complex relationship between secession attempts, exploitation natural resources, fragmentation states. Using archival primary secondary sources, this study unpacks dynamics with a focus on resources. The research question...
From an analysis of pionic atom data the isoscalar (N = Z) nuclei we find for first time a unique description s-wave interaction which is based mainly on experimental data. The coefficients optical potential are 0 - 0.0070(18)mπ-1 and [- 0.270(23) + i × 0.127(7)]mπ-4. These values refer to expressed in terms directly measured nuclear-charge distributions.
The strong-interaction effects both in pionic hydrogen and deuterium atoms have been re-determined with improved precision. hadronic shift width together the constitute a one-fold constraint for two independent pion-nucleon scattering lengths. Furthermore, measures transition strength of s-wave pions on an isoscalar nucleon-nucleon pair which is quantity not related to experiment was performed at Paul Scherrer Institute by stopping high-intensity low-energy pion beam gaseous targets using...