- Nanoplatforms for cancer theranostics
- Metal-Organic Frameworks: Synthesis and Applications
- Extracellular vesicles in disease
- Advanced Nanomaterials in Catalysis
- Nanomaterials and Printing Technologies
- Advanced Sensor and Energy Harvesting Materials
- Evacuation and Crowd Dynamics
- Infection Control and Ventilation
- Nanocluster Synthesis and Applications
- Fire dynamics and safety research
- Wind and Air Flow Studies
- Cancer Immunotherapy and Biomarkers
- RNA Interference and Gene Delivery
- Nanofabrication and Lithography Techniques
- Pressure Ulcer Prevention and Management
- Fire Detection and Safety Systems
- Aerodynamics and Fluid Dynamics Research
- Indoor Air Quality and Microbial Exposure
- Additive Manufacturing Materials and Processes
- SARS-CoV-2 detection and testing
- Luminescence and Fluorescent Materials
- ATP Synthase and ATPases Research
- Immune cells in cancer
- High Entropy Alloys Studies
- Dendrimers and Hyperbranched Polymers
Wuhan University of Technology
2023-2025
China Jiliang University
2024
Soochow University
2017-2023
Jingdezhen Ceramic Institute
2021-2022
Jingdezhen University
2021
China Academy of Engineering Physics
2020
Abstract Near‐infrared (NIR)‐light‐triggered photothermal therapy (PTT) usually requires hyperthermia to >50 °C for effective tumor ablation, which can potentially induce inflammatory disease and heating damage of normal organs nearby, while lesions without sufficient (e.g., the internal part) may survive after treatment. Achieving killing under relatively low temperatures is thus critical toward successful clinical use PTT. Herein, we design a simple strategy fabricate poly(ethylene...
Abstract Radiotherapy (RT) is an extensively used strategy for cancer treatment, but its therapeutic effect usually limited by the abnormal tumor microenvironment (TME) and it lacks ability to control metastases. In this work, a nanoscale coordination polymer, Hf‐nIm@PEG (HNP), prepared of hafnium ions (Hf 4+ ) with 2‐nitroimidazole (2‐nIm), then modified lipid bilayers containing poly(ethylene glycol) (PEG). Under low‐dose X‐ray irradiation, on one hand, Hf high computed tomography signal...
Ultra-small Fe-GA coordination nanoparticles synthesized by a one-step assembly method were used for chelator-free labeling and multimodal imaging-guided photothermal therapy.
Despite the great promise achieved by immune checkpoint blockade (ICB) therapy in harnessing system to combat different tumors, limitations such as low objective response rates and adverse effects remain be resolved. Here, an anti-inflammatory nanofiber hydrogel self-assembled steroid drugs is developed for local delivery of antiprogrammed cell death protein ligand 1 (αPDL1). Interestingly, on one hand this carrier-free based can reprogram pro-tumoral immunosuppressive tumor microenvironment...
Current mainstream cancer treatment methods have their limitations. New approaches are thus desired to assist our battle against cancer. Herein, multifunctional ultrasmall FeS2 nanodots with the size of 7 nm synthesized by biomineralization and used for imaging-guided combined tumor therapy. Bovine serum albumin (BSA), which acts as reaction template induce mineralization nanomaterials under alkaline conditions, could also be a drug delivery system coupling photosensitive molecule such...
Significance The recently emerged SARS-CoV-2 variants are more transmissible, which brings new challenges to vaccine treatment. There is an urgent global need for alternative strategies that could effectively and rapidly prevent the infection of various variants. Herein, we design human angiotensin-converting enzyme II (hACE2)–containing nanocatchers (NCs) derived from genetically engineered cells stably expressing hACE2 as competitor with host virus binding protect infection. An inhalable...
Wound healing is a complex biological process including hemostasis, cell proliferation, and tissue remodeling, which closely associated with the level of oxidative stress within impaired skin. The excessive reactive oxygen species (ROS) generated in injured site detrimental to wound‐healing via series elicited effects such as cellular senescence, fibrotic scarring, inflammation. Herein, novel ROS‐scavenging suture developed by coating surgical sutures gallic acid (GA)‐based nanoparticles...
Open AccessCCS ChemistryRESEARCH ARTICLE1 Oct 2021Coordination Polymers Integrating Metalloimmunology with Immune Modulation to Elicit Robust Cancer Chemoimmunotherapy Longlong Tian, Yujie Zhu, Jun Xu, Ming Shao, Wenjun Zhisheng Xiao, Qian Chen and Zhuang Liu Tian Institute of Molecular Medicine, Renji Hospital, School Shanghai Jiao Tong University, 200127 , Zhu Functional Nano Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Devices, Soochow Suzhou, 215123 Xu Shao Xiao...
Natural ventilation is a passive building technology that can reduce energy consumption for mechanical cooling of the indoor environment. has received renewed attention from researchers. Theoretical studies on natural have evolved steady state to non-steady state. Pumping distinct other ways in its flow direction alternatingly changes outdoor. However, all published did not consider influence internal heat sources pumping ventilation, and there are few discussions about fluid periodic...
Silver nanowires transparent conductive films (AgNWs-TCFs) prepared by traditional rotary coating method, which will cause the failure of channels AgNWs-TCFs under current load because their AgNWs distributing randomly, were restricted its industrial application flexible electronic devices. In this paper, aligned deposited using shear force from high-speed rotating concentrated nanowire solution. Based on rheological performance test results, preparation conditions set at solution 2.0 mg/mL...
Silver nanowire (AgNWs) transparent conductive film (TCF) is considered to be the most favorable material replace indium tin oxide (ITO) as next-generation film. However, disadvantages of AgNWs, such easy oxidation and high wire-wire junction resistance, dramatically limit its commercial application. In this paper, moisture treatment was adopted, water dripped on surface AgNWs or breathed so that covered with a layer vapor. The morphology silver mesh nodes complex, curvature large. According...
One-dimensional nanoscale coordination polymers (1D NCPs) are fabricated by Lai Xu, Meiwan Chen, Zhuang Liu, and co-workers simply mixing metal ions the organic ligand indocyanine green together with polyhistidine–poly(ethylene-glycol) copolymer, then further loading gambogic acid, as described in article number 1703588. Such 1D NCPs efficient pH-responsive tumor retention enables effective destruction of tumors under low-temperature photothermal heating, owing to gambogic-acid-induced...
The development of a highly efficient, nondestructive, and in vitro/vivo-applicable universal delivery strategy therapeutic macromolecules into desired cells tissues is very challenging. Photothermal methods have advantages intracellular delivery, particularly vivo manipulation. However, the inability directional transmission exogenous molecules limits their efficiency. Here, photothermal pump (PTP) patch with numerous "exogenous molecular reservoirs" reported. Under laser, cell membrane...
Pumping airflow occurs in single-sided natural ventilation buildings when the openings are located on leeward side; direction of through building then changes periodicity. In order to propose a calculation method rates for single-room and analyze pumping multi-room buildings, CFD with an SST k-ω turbulence model was used conduct numerical simulation this study, which is verified by other experimental results. Firstly, qualitative quantitative characteristics were investigated two openings....