Haihan Yu

ORCID: 0009-0008-6499-4223
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About
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Research Areas
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Advanced Photocatalysis Techniques
  • Covalent Organic Framework Applications
  • Acute Ischemic Stroke Management
  • Perovskite Materials and Applications
  • Cerebrovascular and Carotid Artery Diseases
  • Multiple Sclerosis Research Studies
  • Neurosurgical Procedures and Complications
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mitochondrial Function and Pathology
  • Peripheral Neuropathies and Disorders
  • Metal-Organic Frameworks: Synthesis and Applications
  • Immune cells in cancer
  • Nanocluster Synthesis and Applications
  • ZnO doping and properties
  • Cardiac Ischemia and Reperfusion
  • T-cell and B-cell Immunology
  • Thermal properties of materials
  • Advanced Neuroimaging Techniques and Applications
  • Thermodynamic and Structural Properties of Metals and Alloys
  • Long-Term Effects of COVID-19
  • Ferroptosis and cancer prognosis
  • Traditional Chinese Medicine Analysis
  • Heme Oxygenase-1 and Carbon Monoxide
  • Kruppel-like factors research

Fujian University of Technology
2023-2025

First Affiliated Hospital of Zhengzhou University
2024

University of Jinan
2023-2024

University of Science and Technology of China
2024

Huazhong University of Science and Technology
2017-2023

Tongji Hospital
2017-2023

Institute of High Energy Physics
2022

University of Chinese Academy of Sciences
2022

Background and Purpose: Information on stroke survivors infected with coronavirus disease 2019 (COVID-19) is limited. The aim of this study was to describe specific clinical characteristics outcomes patients COVID-19 a history stroke. Methods: All the confirmed cases at Tongji Hospital from January 27 March 5, 2020, were included in our cohort study. Clinical data analyzed compared between without Results: Of 1875 COVID-19, 50 had medical older more comorbidities, higher neutrophil count,...

10.1161/strokeaha.120.030365 article EN other-oa Stroke 2020-05-29

Abstract Intramolecular charge separation driving force and linkage chemistry between building blocks are critical factors for enhancing the photocatalytic performance of metal‐covalent organic framework (MCOF) based photocatalyst. However, robust achieving both simultaneously has yet to be challenging despite ongoing efforts. Here we develop a fully π‐conjugated vinylene‐linked multivariate donor‐π‐acceptor MCOF (D‐π‐A, termed UJN‐1) by integrating benzyl cyanides linker with multiple...

10.1002/anie.202409925 article EN Angewandte Chemie International Edition 2024-09-03

Abstract Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, with ~50 million people experiencing TBI each year. Ferroptosis, form regulated cell triggered by iron ion-catalyzed reactive oxygen species-induced lipid peroxidation, has been identified as potential contributor to traumatic central nervous system conditions, suggesting its involvement in the pathogenesis TBI. Alterations metabolism play crucial role secondary following This study aimed explore...

10.1093/burnst/tkad051 article EN cc-by Burns & Trauma 2024-01-01

Oxidative stress is a crucial pathological process that contributes to secondary injury following intracerebral hemorrhage. P2X7 receptor (P2X7R), which activated by the abnormal accumulation of extracellular ATP, plays an important role in regulation oxidative central nervous system, although effects P2X7R-associated after hemorrhage remain unclear. Mouse models were established through stereotactic injection 0.075 U VII collagenase into right basal ganglia. The results revealed P2X7R...

10.4103/1673-5374.303036 article EN Neural Regeneration Research 2021-01-01

Economic losses in the car rental industry due to customer breaches remain a critical issue. The rapid growth of vehicle leasing market has given rise pressing concern for enterprises, namely economic loss, idleness, and service quality degradation that are often associated with default. This study proposes an innovative early warning system incorporates improved DBSCAN clustering technique iTransformer model. enhanced technique, which employs snow ablation optimizer (SAO) algorithm,...

10.1371/journal.pone.0319786 article EN cc-by PLoS ONE 2025-03-20

Transient ischemic attack (TIA) has been widely regarded as a clinical entity. Even though magnetic resonance imaging (MRI) results of TIA patients are negative, potential neurovascular damage might be present, and may account for long-term cognitive impairment. Animal models that simulate human diseases essential tools in-depth study TIA. Previous studies have clarified Dl-3-N-butylphthalide (NBP) promotes angiogenesis after stroke. However, the effects NBP on remain unknown. This aims to...

10.3389/fphar.2021.751397 article EN cc-by Frontiers in Pharmacology 2021-09-29

Background Remote limb ischemic postconditioning (RLIPoC) has been demonstrated to protect against stroke. However, the underlying mechanisms of RLIPoC mediating cross‐organ protection remain be fully elucidated. Methods and Results Ischemic stroke was induced by middle cerebral artery occlusion for 60 minutes. performed with 3 cycles 10‐minute ischemia followed reperfusion bilateral femoral arteries immediately after reperfusion. The percentage regulatory T cells (Tregs) in spleen, blood,...

10.1161/jaha.121.023077 article EN cc-by-nc-nd Journal of the American Heart Association 2021-11-02

Promoting the effective separation of photo-generated charge carriers is vitally crucial to enhancing photocatalytic performance. The piezo-phototronic effect, which could regulate directional migration photogenerated carriers, has been regarded as an strategy separating carriers. Herein, NaNbO3@ZIF-8 possesses efficient carrier property prepared achieve significant increase H2 evolution rate (1.16 mmol g−1 h−1) under coupling effects ultrasonic vibration and light irradiation, 1.9 times...

10.1016/j.catcom.2023.106713 article EN cc-by-nc-nd Catalysis Communications 2023-06-12

Stem cell therapy has emerged as a new promising therapeutic strategy for intracerebral hemorrhage (ICH). However, the efficiency of stem is partially limited by low retention and engraftment delivered cells. Therefore, it's necessary to improve migration ability cells injured area in order save costs duration preparation. This study aimed investigate whether overexpression CX3CR1, specific receptor chemokine fractalkine (FKN), adipose-derived (ADSCs) can stimulate brain, functional recovery...

10.3389/fnins.2019.00462 article EN cc-by Frontiers in Neuroscience 2019-05-08

The flexible job shop scheduling problem (FJSP), one of the core problems in field generative manufacturing process planning, has become a hotspot and challenge production research. In this study, an improved self-learning genetic algorithm is proposed. single mutation approach was improved, while four operators were designed on basis coding machine coding; their weights updated selection adjusted according to performance iterative process. Combined with population initialization method...

10.3390/math11224700 article EN cc-by Mathematics 2023-11-20

Catalytic bioparts are fundamental to the design, construction and optimization of biological systems for specific metabolic pathways. However, functional characterization information these is frequently dispersed across multiple databases literature sources, posing significant challenges effective design chassis or cell factories. We developed Registry Database Bioparts Synthetic Biology (RDBSB), a comprehensive resource encompassing 83 193 curated catalytic with experimental evidences....

10.1093/nar/gkae844 article EN cc-by Nucleic Acids Research 2024-10-03

Hyperhomocysteinemia (HHcy) is independently associated with poorer long-term prognosis in patients intracerebral haemorrhage (ICH); however, the effect and mechanisms of HHcy on ICH are still unclear. Here, we evaluated neurite outgrowth neurological functional recovery using simulated models vitro vivo. We found that velocity motor plus group were significantly slower than control group, indicating homocysteine (Hcy) impedes after ICH. Furthermore, phosphoproteomic data signalome analysis...

10.1136/svn-2022-002165 article EN cc-by-nc Stroke and Vascular Neurology 2023-02-28
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