A5101531811- Cutaneous Melanoma Detection and Management
- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Retirement, Disability, and Employment
- Skin Protection and Aging
- Geriatric Care and Nursing Homes
- Cancer Risks and Factors
- Gastrointestinal disorders and treatments
- Ear and Head Tumors
- melanin and skin pigmentation
- Insurance, Mortality, Demography, Risk Management
- Cardiac Arrhythmias and Treatments
- Cutaneous lymphoproliferative disorders research
- Colorectal and Anal Carcinomas
- CAR-T cell therapy research
- Medical Imaging and Pathology Studies
- Migration, Aging, and Tourism Studies
- Tumors and Oncological Cases
- Reformation and Early Modern Christianity
- Health Systems, Economic Evaluations, Quality of Life
- Sarcoma Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Soft tissue tumor case studies
The University of Texas Southwestern Medical Center
1989-2023
Augusta University
2022
University of Mississippi Medical Center
2020-2022
Dartmouth College
1996-2019
Dartmouth Institute for Health Policy and Clinical Practice
2017
USC Norris Comprehensive Cancer Center
2017
Cotton (United States)
2017
Dartmouth Hospital
2013
National Institute of Environmental Health Sciences
2005
University of New Mexico
1972-2001
Lung cancer is the largest contributor to mortality from cancer. The National Screening Trial (NLST) showed that screening with low-dose helical computed tomography (CT) rather than chest radiography reduced lung We describe screening, diagnosis, and limited treatment results initial round of in NLST inform improve lung-cancer-screening programs.
Interpreting Cancer Mortality The authors use 40 years of data on cancer incidence and mortality to produce curves that show changes in (decreasing, increasing, or staying stable) ...
<h3>Importance</h3> While computed tomography (CT) represents a tremendous advance in diagnostic imaging, it also creates the problem of incidental detection—the identification tumors unrelated to clinical symptoms that initiate test. <h3>Objective</h3> To determine geographic variation United States CT imaging and corresponding association with one most consequential sequelae detection: nephrectomy. <h3>Design, Setting, Participants</h3> This study is cross-sectional analysis age-, sex-,...
Polybrominated diphenyl ethers (PBDEs), used as flame retardants, have been detected in the environment and mammalian tissues fluids. Evidence indicates that PBDE mixtures induce CYPs through aryl hydrocarbon receptor (AhR)-dependent -independent pathways. The present work has investigated effects of individual components a commercial mixture (DE71) on expression CYP1A1, biomarker for activation AhR (dioxin-like), CYP2B CYP3A, biomarkers constitutive androstane pregnane×receptors (CAR PXR),...
A patient with chronic iron deficiency anemia was shown to have multiple gastric filling defects. These were found be ulcerated carcinoid tumors. In the partial gastrectomy specimen innumerable carcinoids arose from a unique diffuse hyperplasia of argyrophil cells. Histochemically and ultrastructurally hyperplastic neoplastic cells identical. closely resembled both bronchial tumors in control human stomachs as well mucosa mice bats. compared those tumor ileum; they appeared histochemically...
BACKGROUND The National Lung Screening Trial (NLST) demonstrated that low‐dose computed tomography screening is an effective way of reducing lung cancer (LC) mortality. However, optimal strategies have not been determined to date and it uncertain whether lighter smokers than those examined in the NLST may also benefit from screening. To address these questions, necessary first develop LC natural history models can reproduce outcomes simulate programs at population level. METHODS Five...
The clinical and pathological characteristics of gallbladder carcinoma were studied in a group 56 Southwestern American Indian patients. This is the third most common malignant tumor among females population served by New Mexico Tumor Registry accounting for 8.5% specific cancer diagnoses site. Carcinoma relatively more within than Spanish Americans or Anglos living this area. true both sexes. No significant differences average age at diagnosis, ratio female to male patients, signs symptoms,...
The Surgical Pathology of Parathyroid Chief Cell Hyperplasia Get access William C. Black, M.D., M.D. Departments and Surgery, Division Pathology, Washitigton University School Medicine Barnes Hospital, St. Louis, Missouri 63110 Search for other works by this author on: Oxford Academic Google Scholar Roderick Haff, American Journal Clinical Volume 53, Issue 5, 1 May 1970, Pages 565–579, https://doi.org/10.1093/ajcp/53.5.565 Published: 01 1970 Article history Received: 02 June 1969 Accepted:...
Excision biopsies of 500 invasive superficial spreading melanomas were examined for evidence residual melanocytic dysplasia (remnants dysplastic nevi). Melanocytic was identified in 32.4% tumors. Remnants nevi without found 9.8%. Sun damage as evidenced by solar elastosis histologically estimated contiguous skin. Patients' age at diagnosis, tumor site, pathologic stage, regression, and coexisting sun correlated with the presence or absence dysplasia. Patients whose tumors displayed younger...
All forms of skin cancer are uncommon among southwestern American Indians. The estimated average annual incidence melanoma is approximately 1 per hundred thousand population or less than one tenth that currently reported for Anglos (non-Hispanic whites) residing in the same region. This study correlates clinical and pathologic features 18 Indian patients. A marked predilection palms, soles, subungual locations was displayed. Additionally, three patients presented with mucous membrane...
In melanoma kindreds the presence of dysplastic nevi correlates with greatly increased risk. The relative importance sporadic, nonfamilial as a risk factor for is less certain. Although clinical features have been well described, histologic basis diagnosis not firmly established. This study examines degree correspondence between and histopathologic nevus. Histologic review dysplasia from 1,000 individuals demonstrated classic (as previously in kindreds) 54.7%. 20.4% patients, displayed...
• The New Mexico Melanoma Registry and Tumor identified 81 cases of melanoma involving the skin mucous membranes Hispanics. clinical pathologic characteristics these tumors were compared with those observed in whites. frequency Hispanics appears to be no more than a sixth that Female patients prevalent within Hispanic population. median patient age at diagnosis was similar A much larger proportion melanomas occurred on palms, soles, subungual regions. Acral lentiginous correspondingly...
Seven patients who had tumors arising in the anterior face or parafiasai sinuses and invasion of skull base were evaluated with magnetic resonance (MR) high resolution CT. Magnetic was superior evaluating tumor encasement carotid artery cavernous sinus; for assessing relationship to brain, optic nerves, chiasm; providing coronal images free from dental artifact; determining extent within infratemporal fossa. Bone destruction more easily observed on CT than MR.
The treatment of salivary gland tumors has not changed significantly in the past two decades. However, increase geriatric population with these poses a new challenge for their management. This study explores incidence-based mortality trends and non-geriatric time period 2000 - 2014 compares between races.Mortality data were extracted from Surveillance, Epidemiology, End Results (SEER) Database years 2014. Incidence-based all stages was queried results grouped by age (geriatric vs. determined...
Primary carcinomas of the breast were studied in age-matched populations Southwestern American Indian, Spanish American, and Anglo women from an area served by New Mexico Tumor Registry. Histologic tumor type, nuclear grade, stromal inflammatory response compared among these three groups. Indian presented with less favorable stage at diagnosis. types similar exception that lobular carcinoma was frequent than women. Carcinomas patients showed differentiated nuclei those other