- Osteoarthritis Treatment and Mechanisms
- Inflammatory mediators and NSAID effects
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Peroxisome Proliferator-Activated Receptors
- Eicosanoids and Hypertension Pharmacology
- Venous Thromboembolism Diagnosis and Management
- Chemokine receptors and signaling
- Adipokines, Inflammation, and Metabolic Diseases
- Intestinal and Peritoneal Adhesions
- Extracellular vesicles in disease
- Sarcoma Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Cardiovascular Health and Disease Prevention
- High Altitude and Hypoxia
- Cardiovascular Effects of Exercise
- Fatty Acid Research and Health
- Medical Imaging and Pathology Studies
- Ovarian function and disorders
- Tumors and Oncological Cases
- Wound Healing and Treatments
- Surgical site infection prevention
- Eosinophilic Disorders and Syndromes
- Hernia repair and management
Siddhartha Medical College
2023-2024
Institute of Medical Sciences
2023-2024
Jinnah Sindh Medical University
2023
Karachi Medical and Dental College
2023
Khawaja Farid Social Security Hospital
2023
Universidad Nacional Autónoma de México
2023
University of Lahore
2023
Windsor Dermatology
2023
University of Montemorelos
2023
Punjab Medical College
2023
Recent advances in cancer treatment emphasize the pivotal role of extracellular vesicles (EVs), especially exosomes (a subpopulation EVs, originating from endosomes). Exosomes are signaling molecules cellular system. Its molecular signature displays status cell (cell healthy or undergoing any clinical complication). frontiers upcoming theranostics era. This article highlighted exosome complex interlink, advantage exosome-base liquid biopsy, effectiveness exosome-based cell-free therapy...
Objective Bioactive oxidised lipids (oxylipins) are important signalling mediators, capable of modulating the inflammatory state joint and anticipated to be importance in homeostasis status osteoarthritis. The aim this study was quantify oxylipin levels plasma synovial fluid from rats with experimentally induced osteoarthritis investigate potential role oxylipins as a marker disease process early Design Forty were randomly allocated standard or high-fat diet group. After 12 weeks, local...
Open fractures with extensive soft-tissue damage, significant periosteal stripping, and exposed bone ends pose a challenge in orthopaedics. So, we conducted prospective study that investigated the efficacy of vacuum-assisted closure (VAC) therapy improving functional outcomes for orthopaedic open wounds.
Abstract Lipomas are common benign mesenchymal tumours, whereas lipomatoses uncommon. Familial multiple lipomatosis (FML) is a rare syndrome characterized by usually painless lipomas which may be associated with other conditions. FML considered to genetic, various patterns of inheritance suggested. In this case report, we described familial that was misdiagnosed as dercum’s disease.
Abstract Background Since the efficacy and safety of endovascular thrombectomy (EVT) in patients with acute ischemic stroke a large infarct area is still inconclusive, we sought to compare functional neurological outcomes use versus medical care alone. Methods We searched MEDLINE (via PubMed), Embase, Cochrane Library, ClinicalTrials.gov, International Clinical Trials Registry Platform (ICTRP) retrieve all relevant randomized controlled trials (RCTs) on this topic. Review manager (RevMan)...
Abstract Intestinal obstruction is a common surgical emergency that requires prompt intervention. We present case report of 30-year-old male with recurrent intestinal due to sigmoid volvulus. Our highlights the challenges associated managing obstructions caused by adhesions following interventions for It emphasizes need careful evaluation and meticulous techniques minimize risk adhesion formation subsequent complications.
Abstract Background In this study we investigated the contribution of high-fat diet-induced metabolic overload to osteoarthritis (OA) progression originally caused by mild mechanical trauma mouse knee joint. We hypothesized that stress would induce a proinflammatory environment altering systemic lipid levels and immune cell populations. Methods Twelve-week-old male C57BL/6J mice (n=20) were given low-fat diet (LFD, 10%kcal from fat) or (HFD, 45%kcal for 18 weeks. OA was initiated transecting...