Azam Askari

ORCID: 0009-0008-8917-7262
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About
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Research Areas
  • Protein Interaction Studies and Fluorescence Analysis
  • DNA and Nucleic Acid Chemistry
  • Neuroscience and Neuropharmacology Research
  • bioluminescence and chemiluminescence research
  • Drug Transport and Resistance Mechanisms
  • Photoreceptor and optogenetics research
  • Metal complexes synthesis and properties
  • Porphyrin Metabolism and Disorders
  • Antibiotics Pharmacokinetics and Efficacy

University of Guelph
2023

Islamic Azad University, Mashhad
2018-2021

The present study was designed to investigate the influence of two indispensable and dispensable amino acids, including methionine, histidine, cysteine proline, on binding interaction between human serum albumin (HSA) an antibiotic agent lomefloxacin (LMF). fluorescence quenching experiments showed that intrinsic emission HSA considerably quenched following LMF in all systems. Furthermore, interactions maximum wavelength slightly decreased. spectral changes observed systems we e attributed...

10.1080/07391102.2018.1491421 article EN Journal of Biomolecular Structure and Dynamics 2018-07-26

Kalium channelrhodopsin 1 from Hyphochytrium catenoides (HcKCR1) is a light-gated channel used for optogenetic silencing of mammalian neurons. It selects K

10.1038/s41467-023-40041-2 article EN cc-by Nature Communications 2023-07-20

This study aimed to evaluate the role of linker histone (H1) in binding interaction between ambochlorin (Amb), and calf thymus DNA (ctDNA) as binary ternary systems.The project was accomplished through means absorbance, fluorescence, stopped-flow circular dichroism spectroscopy, viscosity, thermal melting, molecular modeling techniques.Spectroscopic analysis revealed that although Amb strongly bound both ctDNA ctDNA-H1, it showed a greater tendency presence histone. The obtained...

10.22038/ijbms.2021.58829.13070 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2021-11-01
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