Aleksandra Safonova

ORCID: 0009-0008-9155-8531
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • Cardiac Structural Anomalies and Repair
  • Glycogen Storage Diseases and Myoclonus
  • Intensive Care Unit Cognitive Disorders
  • Lysosomal Storage Disorders Research
  • Heart Failure Treatment and Management
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Drug-Induced Adverse Reactions
  • Pharmacological Receptor Mechanisms and Effects
  • Mechanical Circulatory Support Devices
  • Biotin and Related Studies
  • Cystic Fibrosis Research Advances
  • Human Health and Disease
  • Pneumonia and Respiratory Infections
  • Advanced biosensing and bioanalysis techniques
  • COVID-19 and healthcare impacts

Federal Almazov North-West Medical Research Centre
2024

University of Pittsburgh
2021

Clinical Research Consortium
2021

Siberian State Medical University
2013

<h3>Importance</h3> The COVID-19 pandemic continues to affect millions of people globally, with increasing reports neurological manifestations but limited data on their incidence and associations outcome. <h3>Objective</h3> To determine the phenotypes, incidence, outcomes among adults hospitalized COVID-19. <h3>Design, Setting, Participants</h3> This cohort study included patients clinically diagnosed or laboratory-confirmed at 28 centers, representing 13 countries 4 continents. was...

10.1001/jamanetworkopen.2021.12131 article EN cc-by-nc-nd JAMA Network Open 2021-05-11

The work is devoted to the study of atrial natriuretic peptide (ANP) and its precursors as one possible predictors left ventricular repeated remodeling in patients with ischemic cardiomyopathy (ICMP) follow-up (postoperative period). Objects are venous blood intraoperative samples right auricle. Precursors NUP were identified serum by immuno-fluorescence test. Ultrathin slices auricle biopsy examined electronmicroscopy use image processing ImageJ software (program). concentration plasma...

10.20538/1682-0363-2013-6-23-30 article EN cc-by Bulletin of Siberian Medicine 2013-12-28

The aim: to determine the impact of a new coronavirus infection on course pneumocystis pneumonia in patients with HIV infection. Materials and methods. A retrospective analysis 45 medical records who died intensive care unit S. P. Botkin Clinical Infectious Diseases Hospital between March 2020 January 2023 was conducted. Of Pneumocystis pneumonia, also verified 26 patients. Anamnestic clinical data, laboratory instrumental research results, pathological findings were compared groups...

10.22328/2077-9828-2024-16-3-53-59 article EN HIV Infection and Immunosuppressive Disorders 2024-11-28

Objective: To identify major phenotypes of neurologic manifestations and their prevalence in hospitalized patients infected with severe acute respiratory syndrome corona virus disease 2019 (COVID-19). Background: Emerging evidence suggests COVID-19 presentation is not limited to the system but may have multi-organ involvement including dysfunctions nervous system. However, little known about phenotypes, prevalence, impact on patient outcomes. Design/Methods: We are coordinating center part...

10.1212/wnl.96.15_supplement.1718 article EN Neurology 2021-04-13

Objective: Evaluate impact of COVID-19 pandemic on mortality and care limitations in critically-ill stroke patients. Background: overwhelmed medical systems leading to resource shortages many regions, which may non-COVID This is particular concern severe population where perceived poor prognosis can lead early the self-fulfilling prophecy worse outcomes. Design/Methods: During first 3 months (03/28/30-06/28/20) we prospectively enrolled consecutive adults with acute ischemic (AIS),...

10.1212/wnl.96.15_supplement.4551 article EN Neurology 2021-04-13

Determine outcomes of hospitalized adult patients with severe acute respiratory syndrome coronavirus disease-2019 (COVID-19) and neurological dysfunction.

10.1212/wnl.96.15_supplement.2053 article EN Neurology 2021-04-13
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